The invention discloses a culturing method of one-ridge double-row flue-cured tobacco dislocation, comprising the following steps: (1) selecting tobacco field and preparing soil; (2) ridging; (3) applying base fertilizer; (4) transplanting; and (5) uncovering film, ridging and loading. The method has the following advantages that: (1) on the premise that the use amount of fertilizer for soil in unit area is not changed, the fertilizer use amount of single plant in flue-cured tobacco field is reduced, and the use amount of field organic fertilizer, especially oil cake fertilizer is increased to lead the field tobacco plant to present the growth of middle-plant tobacco, thus obviously improving the tobacco leaf quality; (2) compared with the conventional single ridge, the one-ridge double-row tobacco reduces the labor capability of ridging by about one third, the ridging height is obvious lower than the conventional height, thus reducing ridging labor intensity of tobacco growers; and (3) the one-ridge double-row flue-cured tobacco increases flue-cured tobacco planting density, and meanwhile, a dislocated equal plant distance planting method improves utilization rate of tobacco field to the utmost, ensures the housework operation of tobacco growers, and the row space of the ridge just satisfies growth space of tobacco plants in the field, thus ensuring the income of the tobacco growers.