The invention relates to a thickness deviation-on-plate control method of a cold-rolled sheet. The invention adopts a cold rolling absolute thickness difference thickness deviation-on-plate control mode, a difference value of center thickness of strip steel and a set thickness value is calculated correspondingly so as to ensure the control mode of the thickness deviation-on-plate of the strip steel whole plate, the small fluctuation of the thickness of an edge part in the length direction of the strip steel is guaranteed, and a control strategy of bending roll first and displacement later is adopted; and a control scheme of the thickness deviation-on-plate thickness absolute value refers to the fact that when the thickness deviation-on-plate is controlled, an absolute value thickness control mode is adopted, a control mode is implemented according to a each thickness value of a transverse position. According to the method, a thickness deviation-on-plate overall level in a cold rollingrolling process can be enhanced, the thickness deviation-on-plate of a cold rolling high-thickness and high-precision product is improved, the cold rolling product quality is improved, the shearing amount is reduced, and the productivity is improved; the problems that an existing control mode is poor in control effect on the thickness deviation-on-plate, the length and width of the thickness valuesituation of the strip steel whole plate cannot be comprehensively reflected, and the yield is low are solved.