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1 results about "Autoimmune antibody" patented technology

Autoimmune antibodies are groups of immune proteins that can be damaging to the human body, as they target tissues and organs and cause deterioration.

Discovery and application of desmin autoantibody as a marker of nervous system disease

PendingCN122449133AImmunologic disordersDesmin
The application discloses discovery and application of desmin autoantibody as a marker of nervous system diseases. The application finds that only the fluorescent signal existing in the nervous system disease patients but not in the healthy people, and the fluorescent mode of the IgG related autoimmune antibody in the mouse brain tissue section is different, which indicates that the patient may have autoimmune antibody. Through the immunoprecipitation technology, the IgG specific protein related to the nervous system disease is sought, the specific desmin autoantibody is found by adopting the CBA mode, and then the desmin autoantibody is verified in the cerebrospinal fluid, so that it is finally determined that the desmin autoantibody can be used as a specific marker for diagnosing the nervous system autoimmune diseases. The expression of the desmin autoantibody is detected by taking the desmin as a detection antigen, and the detection of the desmin autoantibody can be applied to a kit for detecting the desmin autoantibody, and can be applied to the detection of the nervous system diseases, so that the marker for identifying the nervous system diseases is enriched, and the accuracy of the detection of the nervous system related diseases is improved.
Owner:FIRST HOSPITAL OF SHANXI MEDICAL UNIV