3 results about "Autoimmune antibody" patented technology

The invention relates to the field of biological medicines, and discloses application of an OGG1 micromolecule agonist in preparation of a medicine for treating liver inflammatory diseases. According to the micromolecule TH10785, by activating the beta, delta-lyase activity of DNA repair enzyme OGG1, the oxidized DNA repair capacity is remarkably enhanced, ROS accumulation in liver cells is reduced, NF-kappa B signal channel activation and proinflammatory factor release are inhibited, and therefore liver inflammation and fibrosis are effectively relieved. Meanwhile, the medicine can inhibit the activation of B cells and the formation of plasma cells, finally reduces the generation of autoimmune antibodies, and improves the immune imbalance state of autoimmune hepatitis. The invention provides an innovative treatment strategy based on OGG1 enzyme function amplification, and a new pharmacological approach is provided for treatment of chronic liver diseases and immunological liver injury.

The utility model discloses an autoimmune antibody inspection device, which comprises a base and a digital display control panel, a turntable is rotatably arranged above the base, a plurality of uniformly distributed intubation sleeves are arranged on the outer side of the turntable along the circumferential direction, and each intubation sleeve is movably provided with a position adjusting support structure along the axial direction of the intubation sleeve; the base is provided with a rotary oscillation assembly used for conducting rotary driving and up-down offset vibration on the rotary disc, the rotary disc, the insertion pipe sleeve, the rotary oscillation assembly and the like cooperate and cooperate with one another, so that samples placed in the insertion pipe sleeve can be subjected to acting force in different directions, mixing and reaction of the samples are promoted, and the accuracy of the samples is improved. And the accuracy of test results is improved.