10 results about "Disease agent" patented technology

The invention discloses an automatic diagnosis algorithm for interpretability-oriented adaptive multi-agent cooperation. The method comprises the following steps: firstly, constructing a bidirectional probability network of symptoms and diseases based on a data set, calculating a disease weight through a pre-diagnosis module, and deciding to enter a Doctor Agent module or a Med-Team Agent module; the Doctor Agent simulates single expert diagnosis and judges whether a patient can be diagnosed or not or continues to inquire related symptoms to assist diagnosis in combination with a medical knowledge base and a bidirectional probability network. The Med-Team Agent is used for simulating consultation of multiple experts, and comprises a Manager Agent and a plurality of Disease Agents which respectively represent an attending physician and a plurality of disease experts. And the Manager Agent dynamically manages a plurality of Disease Agents, selects an appropriate expert to generate related symptoms according to the symptom information of the patient, and finally completes diagnosis. The method is suitable for medical automatic diagnosis tasks, through combination of multi-agent cooperation and bidirectional probability network prompting, the interpretability of diagnosis is improved, and efficient inquiry and accurate diagnosis are achieved.

Agents that target a processed mRNA, e.g., the 5′ UTR of the processed mRNA, can modulate protein expression, e.g., via modulation of translation of the processed mRNA. Alternative splicing events in genes can lead to non-productive mRNA transcripts which in turn can lead to aberrant protein expression. Agents that target the alternative splicing events in genes can modulate the expression level of proteins. Therapeutic agents, which can modulate protein expression by targeting a processed mRNA and / or alternative splicing events, can promote functional protein expression in patients and / or inhibit aberrant protein expression. Such therapeutic agents can be used to treat a condition or disease associated with protein deficiency and / or mitochondrial function deficit.

The present invention relates to a highly effective, broad-spectrum anti-plant viral disease pharmaceutical composition and its application. The active ingredients of the anti-plant viral disease pharmaceutical composition include chlorin iron and lentinan; wherein the weight ratio of chlorin iron to lentinan is 1:6000 to 4:1. When a certain concentration of the chlorin iron and lentinan pharmaceutical composition is applied to plants, the two active ingredients exert a synergistic effect, alleviating symptoms of diseased plants, reducing disease indexes, and reducing viral accumulation in the plants. The plant anti-viral disease pharmaceutical composition is a biological agent that is environmentally friendly, safe, and environmentally friendly. It has important application prospects in combating plant viral diseases, preventing and controlling plant diseases caused by plant viruses, and improving plant quality.

The invention discloses a method for preparing a plant disease-resistant agent by using a biomass carbon nano material and its application. The method uses a biomass material as a raw material, and sequentially sintering, cooling, ball milling, washing and reducing the biomass material to obtain a nano material-level plant disease-resistant agent. The content of O element on the outer surface of the nano material-level plant disease-resistant agent accounts for 18-22% of the total element content on the surface of the material, and the reduction process is carried out under a methane system. The invention reduces the content of O element on the outer surface of the biomass carbon nano material, so that the material itself can better promote the synthesis of hydrogen peroxide in plant tissues. Compared with other disease-resistant preparations of the same type, the amount of hydrogen peroxide produced by the biomass carbon nano material is increased by 98.09%. Because the content of hydrogen peroxide as an endogenous antibacterial compound in plants is increased, the disease resistance of plants is ultimately improved, and no damage is caused to plants and the environment.

The application discloses an automatic diagnosis algorithm for adaptive multi-agent cooperation for explainability. The application comprises the following steps: firstly, a two-way probability network of symptoms and diseases is constructed based on a data set, and a disease weight is calculated through a pre-diagnosis module to determine whether to enter a Doctor Agent module or a Med-Team Agents module. The Doctor Agent simulates single expert diagnosis, combines a medical knowledge base and the two-way probability network, and judges whether a patient can be definitely diagnosed or continue to ask related symptoms to assist in diagnosis. The Med-Team Agents simulate the consultation of multiple experts, including a Manager Agent and multiple Disease Agents, which respectively represent a chief physician and multiple disease experts. The Manager Agent dynamically manages multiple Disease Agents, selects appropriate experts according to the symptom information of the patient to generate related symptoms, and finally completes diagnosis. The application is suitable for medical automatic diagnosis tasks, combines multi-agent cooperation with two-way probability network prompts, improves the explainability of diagnosis, and realizes efficient inquiry and accurate diagnosis.

Methods, compositions and kits are provided for treating a subject exposed to or at risk for exposure to a disease agent, methods, compositions and kits having a pharmaceutical composition including at least one recombinant binding protein or a source of expression of the binding protein, wherein the binding protein neutralizes at least one or a plurality of disease agents that are toxins, for example at least one of a Botulinum toxin or an Anthrax toxin.

The embodiment of the invention provides a medical text information processing method and device, electronic equipment and a storage medium, and relates to the technical field of medical information processing. The method comprises the steps of obtaining unstructured medical text data of a patient, performing semantic normalization processing on term expression and time expression in the unstructured medical text data, and constructing structured prompt information based on an obtained semantic standardized medical text and context metadata associated with the semantic standardized medical text. Performing response analysis on the structured prompt information by using a preset large language model, obtaining original structured clinical data, performing verification and repair processing, obtaining target structured clinical data, inputting the target structured clinical data into a plurality of special disease agent models for parallel reasoning, and generating an intermediate judgment result with a causal interpretation chain; and a comprehensive analysis report is formed through a collaborative fusion mechanism, so that the interpretability and clinical rationality of diagnosis are enhanced, and the robustness of complex complication identification and the overall decision quality are effectively improved.

Relates to the field of agricultural production, and discloses a corn seed disease-resistant treatment device which comprises a support and a treatment box fixedly arranged at the upper end of the support, and further comprises a mixing unit arranged in the treatment box and used for mixing and stirring corn seed raw materials in the treatment box; the heating unit is arranged on the bracket and is used for heating and drying the corn seeds in the treatment box; according to the corn seed treatment device, the adding amount of the anti-disease agent into the treatment box by the chemical adding unit is controlled, the anti-virus agent is driven by the mixing unit to be fully mixed with corn seeds, the corn seeds are fully wrapped by the anti-virus agent, the anti-disease agent is added into the treatment box by the chemical adding unit, and the anti-disease agent is added into the treatment box by the chemical adding unit. The defense effect of the corn seeds on the spike rot can be improved.

The application provides a composite microbial growth-promoting and disease-resistant bactericide, a preparation method and application thereof. The composite microbial growth-promoting and disease-resistant bactericide is prepared by mixing B24 bactericide of Pseudomonas putida and 79-1 bactericide of Bacillus subtilis. Since there is no obvious antagonism between the two, the growth-promoting effect of the B24 bactericide of Pseudomonas putida can be utilized, and the antagonism of the 79-1 bactericide of Bacillus subtilis to J-9, B152 and 617-3 of Fusarium during the growth of crops can be utilized, so that the rapid growth of crops can be effectively promoted.

The invention discloses application of medicagenic acid in preparation of anti-plant fungus biological source drugs, and belongs to the technical field of plant disease control. The invention reveals that the medicagenic acid has a remarkable inhibition effect on the growth of the black beancurd skin fungi, and verifies that the medicagenic acid can improve the expression of resistance genes in plants and activate the defense reaction of the plants, so that the resistance of the plants to fungi is improved. The invention provides a new drug resource and theoretical basis for developing a novel plant disease-resistant agent, fills up the vacancy of antifungal terpenoids, and provides a new thought for biological control of rot diseases in Xinjiang wild fruit forests, cultivated apple orchards and other economic fruit orchards.