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79 results about "Histology type" patented technology
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Histology is an essential tool of biology and medicine. Histopathology, the microscopic study of diseased tissue, is an important tool in anatomical pathology, since accurate diagnosis of cancer and other diseases usually requires histopathological examination of samples.
Apparatus and method for use of RFID catheter intelligence
ActiveUS20070083111A1Easily and securely storeEasily and securely and transferUltrasonic/sonic/infrasonic diagnosticsSurgeryHistology typeComputer science
A method and system is provided for using backscattered data and known parameters to characterize vascular tissue. Specifically, methods and devices for identifying information about the imaging element used to gather the backscattered data are provided in order to permit an operation console having a plurality of Virtual Histology classification trees to select the appropriate VH classification tree for analyzing data gathered using that imaging element. In order to select the appropriate VH database for analyzing data from a specific imaging catheter, it is advantageous to know information regarding the function and performance of the catheter, such as the operating frequency of the catheter and whether it is a rotational or phased-array catheter. The present invention provides a device and method for storing this information on the imaging catheter and communicating the information to the operation console. In addition, information related to additional functions of the catheter may also be stored on the catheter and used to further optimize catheter performance and / or select the appropriate Virtual Histology classification tree for analyzing data from the catheter imaging element.
Owner:VOLCANO CORP
Displaying image data using automatic presets
InactiveUS20050017972A1Easy and intuitiveAccurate classificationUltrasonic/sonic/infrasonic diagnosticsImage enhancementPattern recognitionVoxel
A computer automated method that applies supervised pattern recognition to classify whether voxels in a medical image data set correspond to a tissue type of interest is described. The method comprises a user identifying examples of voxels which correspond to the tissue type of interest and examples of voxels which do not. Characterizing parameters, such as voxel value, local averages and local standard deviations of voxel value are then computed for the identified example voxels. From these characterizing parameters, one or more distinguishing parameters are identified. The distinguishing parameter are those parameters having values which depend on whether or not the voxel with which they are associated corresponds to the tissue type of interest. The distinguishing parameters are then computed for other voxels in the medical image data set, and these voxels are classified on the basis of the value of their distinguishing parameters. The approach allows tissue types which differ only slightly to be distinguished according to a user's wishes.
Owner:VOXAR
Tissue biopsy and treatment apparatus and method
InactiveUS20060241577A1Improve clinical outcomesPrecise positioningUltrasound therapySurgical needlesTissue biopsyTumour volume
A method of treating a tumor includes providing a tissue biopsy and treatment apparatus that includes an elongated delivery device that has a lumen and is maneuverable in tissue. A sensor array having a plurality of resilient members is deployable from the elongated delivery device. At least one of the plurality of resilient members is positionable in the elongated delivery device in a compacted state and deployable with curvature into tissue from the elongated delivery device in a deployed state. At least one of the plurality of resilient members includes at least one of a sensor, a tissue piercing distal end or a lumen. The sensor array has a geometric configuration adapted to volumetrically sample tissue at a tissue site to differentiate or identify tissue at the tissue site. At least one energy delivery device is coupled to one of the sensor array, at least one of the plurality of resilient members or the elongated delivery device. The apparatus is then introduced into a target tissue site. The sensor array is then utilized to distinguish a tissue type. The tissue type information derived from the sensor array is utilized to position the energy delivery device to ablate a tumor volume. Energy is then delivered from the energy delivery device to ablate or necrose at least a portion of the tumor volume. The sensor array is then utilized to determine an amount of tumor volume ablation.
Owner:ANGIODYNAMICS INC
System and method for identifying tissue using low-coherence interferometry
ActiveUS7761139B2Image degradationLower requirementCatheterDiagnostic recording/measuringFiberBiopsy procedure
Owner:THE GENERAL HOSPITAL CORP
Determining biological tissue type
ActiveUS10716489B2Improve accuracySimple and reliable techniqueDiagnostic recording/measuringSensorsComplex impedance spectraData set
A method is described for determining biological tissue type based on a complex impedance spectra obtained from a probe with a conducting part adjacent a tissue region of interest, wherein the impedance spectra includes data from a number of frequencies. The method may include: obtaining, from the complex impedance spectra, a first data set representative of impedance modulus values, or equivalent admittance values, at one or more frequencies, obtaining, from the complex impedance spectra, a second data set representative of impedance phase angle values, or equivalent admittance values, at one or more different frequencies, applying a first discrimination criterion to the first data set, applying a second discrimination criterion to the second data set, and thereby determining if the tissue region of interest is a tissue type characterised by the discrimination criteria.
Owner:UNIV OSLO HF
Methods and compositions for differentiating tissues for cell types using epigenetic markers
InactiveUS20060183128A1Accurate and efficientMicrobiological testing/measurementFermentationGenomic DNAEpigenetic Profile
The present invention provides, inter alia, a method for generating a genome-wide epigenomic map, comprising a correlation between methylation variable CpG positions (MVP) and genomic DNA sample types. MVP are those CpG positions that show a variable quantitative level of methylation between sample types. Particular genomic regions of interest (ROI) provide preferred marker sequences that comprise multiple, and preferably proximate MVP, and that have novel utility for distinguishing sample types. The epigenic maps have broad utility, for example, in identifying sample types, or for distinguishing between and among sample types. In a preferred embodiment the epigenomic map is based on methylation variable regions (MVP) within the major histocompatibility complex (MHC), and has utility, for example, in identifying the cell or tissue source of a genomic DNA sample, or for distinguishing one or more particular cell or tissue types among other cell or tissue types. Analysis of epigenetic characteristics of one, or of a set of nucleic acid sequences, in the context of an inventive epigenomic map, allows for the determination of an origin of the nucleic acids.
Owner:EPIGENOMICS AG
Agents for use in magnetic resonance and optical imaging
InactiveUS20050220714A1High photoluminescence efficiencyBrighter luminescenceUltrasonic/sonic/infrasonic diagnosticsGeneral/multifunctional contrast agentsDual modeSemiconductor Nanoparticles
Semiconductor nanoparticles are doped with paramagnetic ions to serve as dual-mode optical and magnetic resonance imaging (MRI) contrast agents. These nanoparticles can be constructed in smaller diameters than typical MRI agents. The dual-modality nature allows the particles to be used for in vivo imaging by MRI, and then followed by histology with optical imaging techniques.
Owner:RGT UNIV OF CALIFORNIA
Gene profiles correlating with histology and prognosis
InactiveUS20070026424A1Improved prognosisPoor prognosisMicrobiological testing/measurementCancer deathHistology type
The present invention related to methods and kits for evaluating the histology and prognosis of lung cancer by measuring expression levels of specific gene markers. It is based, at least in part, on the discovery of 99 genes that were found to be differentially expressed among lung cancer subtypes, 30 genes which correlate with a high risk, and 12 genes which correlate with a low risk, of cancer death within 12 months.
Owner:POWELL CHARLES A +1
Analysis of fragmentation patterns of cell-free DNA
Factors affecting the fragmentation pattern of cell-free DNA (e.g., plasma DNA) and the applications, including those in molecular diagnostics, of the analysis of cell-free DNA fragmentation patterns are described. Various applications can use a property of a fragmentation pattern to determine a proportional contribution of a particular tissue type, to determine a genotype of a particular tissue type (e.g., fetal tissue in a maternal sample or tumor tissue in a sample from a cancer patient), and / or to identify preferred ending positions for a particular tissue type, which may then be used to determine a proportional contribution of a particular tissue type.
Owner:THE CHINESE UNIVERSITY OF HONG KONG
Ultrasonic strain imaging device with selectable cost-function
ActiveUS20100106018A1Enhance the imageInherent tensionOrgan movement/changes detectionInfrasonic diagnosticsPre deformationTissues types
An elasticity measuring system determines tissue displacement between a pre-deformation and post-deformation image by a matching process using a cost function accepting as its arguments continuity of the tissue motion and correlation of the tissue in making the block matching. The invention allows the selection among different cost functions for different imaging situations or tissue types, to provide improved displacement calculations using a priori knowledge about the tissue and structure of tissue interfaces or information derived during the scanning process.
Owner:WISCONSIN ALUMNI RES FOUND
Iterative optical based histology
InactiveUS20050035305A1Automate analysisWithdrawing sample devicesPhotometryOptical transparencyFluorescence
Femtosecond laser pulses are used to iteratively cut and image fixed as well as exsanguinated fresh tissue. Such images help to automate three-dimensional histological analysis of biological tissue. Cuts are accomplished with approximately 0.3 to 100 microJoule pulses to ablate tissue with one-micrometer precision. Permeability, immunoreactivity, and optical clarity of the remaining tissue is retained after pulsed laser cutting. Samples from transgenic mice that express fluorescent proteins retained their fluorescence to within micrometers of the cut surface.
Owner:RGT UNIV OF CALIFORNIA SAN DIEGO
Size-tagged preferred ends and orientation-aware analysis for measuring properties of cell-free mixtures
Various applications can use fragmentation patterns related of cell-free DNA, e.g., plasma DNA and serum DNA. For example, the end positions of DNA fragments can be used for various applications. The fragmentation patterns of short and long DNA molecules can be associated with different preferred DNA end positions, referred to as size-tagged preferred ends. In another example, the fragmentation patterns relating to tissue-specific open chromatin regions were analyzed. A classification of a proportional contribution of a particular tissue type can be determined in a mixture of cell-free DNA from different tissue types. Additionally, a property of a particular tissue type can be determined, e.g., whether a sequence imbalance exists in a particular region for a tissue type or whether a pathology exists for the tissue type.
Owner:THE CHINESE UNIVERSITY OF HONG KONG +1
System and method for using tissue contact information in an automated mapping of cardiac chambers employing magneticly shaped fields
InactiveUS20100305429A1Effective shapingReserve valid spaceElectrocardiographyCatheterMapping algorithmTissues types
The invention relates to a method for using tissue contact technology to optimize automated cardiac chamber mapping algorithms to both speed up the mapping process and guarantee the definition of the actual chamber limits. The invention further comprises a method for conveying tissue type information to such automatic mapping algorithms so as to allow them to adapt their point collection density within areas of particular interest. The method is enhanced by the use of a magnetic chamber that employs electromagnetic coils configured as a waveguide that radiate magnetic fields by shaping the necessary flux density axis on and around the catheter distal tip so as to push, pull and rotate the tip on demand and as defined by such automatic mapping algorithms.
Owner:MAGNETICS INC +1
System, method, and computer-accessible medium for virtual pancreatography
A system, method, and computer-accessible medium for using medical imaging data to screen for a cystic lesion(s) can include, for example, receiving first imaging information for an organ(s) of a one patient(s), generating second imaging information by performing a segmentation operation on the first imaging information to identify a plurality of tissue types, including a tissue type(s) indicative of the cystic lesion(s), identifying the cystic lesion(s) in the second imaging information, and applying a first classifier and a second classifier to the cystic lesion(s) to classify the cystic lesion(s) into one or more of a plurality of cystic lesion types. The first classifier can be a Random Forest classifier and the second classifier can be a convolutional neural network classifier. The convolutional neural network can include at least 6 convolutional layers, where the at least 6 convolutional layers can include a max-pooling layer(s), a dropout layer(s), and fully-connected layer(s).
Owner:THE RES FOUND OF STATE UNIV OF NEW YORK
Atlas-based analysis for image-based anatomic and functional data of organism
A non-invasive imaging system, including an imaging scanner suitable to generate an imaging signal from a tissue region of a subject under observation, the tissue region having at least one anatomical substructure and more than one constituent tissue type; a signal processing system in communication with the imaging scanner to receive the imaging signal from the imaging scanner; and a data storage unit in communication with the signal processing system, wherein the data storage unit is configured to store a parcellation atlas comprising spatial information of the at least one substructure in the tissue region, wherein the signal processing system is adapted to: reconstruct an image of the tissue region based on the imaging signal; parcellate, based on the parcellation atlas, the at least one anatomical substructure in the image; segment the more than one constituent tissue types in the image; and automatically identify, in the image, a portion of the at least one anatomical substructure that correspond to one of the more than one constituent tissue type.
Owner:THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE
Method and apparatus for multimodal imaging of biological tissue
InactiveUS20120029348A1Increase the number ofEasy to processMaterial analysis by optical meansRadiation diagnosticsRapid imagingTissues types
The present invention is directed to a novel multi-wavelength imaging method and apparatus that enables rapid imaging of tissue regions with accurate identification of tissue types within the region. Optical properties, such as co-polarized or cross-polarized fluorescence or reflectance intensity, optical density and / or reflectance, can be determined at a plurality of locations within the tissue region for each wavelength. Said properties at the two wavelengths, including calculated derivatives of the optical property with respect to wavelength, can be analyzed to image tissue structures and identify tissue types within the tissue region more accurately than can be achieved based on properties measured at a single wavelength.
Owner:THE GENERAL HOSPITAL CORP
Retinal dystrophin transgene and methods of use thereof
InactiveUS20080044393A1Alleviation of muscular dystrophy symptomReduce the possibilityBiocideNervous disorderBehavioral studyTransgene
Duchenne muscular dystrophy (DMD) is a progressive muscle disease that is caused by severe defects in the dystrophin gene and results in the patient's death by the third decade. The present invention utilizes the Double Mutant mice (DM) as an appropriate human model for DMD as these mice are deficient for both dystrophin and utrophin (mdx / +, utrn − / −), die at 3 months of age and suffer from severe muscle weakness, pronounced growth retardation, kyphosis, weight loss, slack posture, and immobility. Expression from a transgene of novel human retinal dystrophin Dp260 was shown to prevent premature death and reduce the severe muscular dystrophy phenotype to a mild clinical myopathy. Electromyography, histology, radiography, magnetic resonance imaging, and behavior studies concluded that DM transgenic mice grew normally, had normal spinal curvature and mobility, and had reduced muscle pathology. EMG and histologic data from transgenic DM mice showed decreased abnormalities to levels typical of mild myopathy, while the DM mice exhibited severe abnormalities commonly seen in human dystrophinopathies. The transgenic DM mice also had measurable movement levels comparable to those of untreated mdx mice and controls.
Owner:WHITE ROBERT L +2
An ultrasound system with a tissue type analyzer
ActiveUS20200049807A1Improve spatial resolutionHigh frequencyMechanical vibrations separationInfrasonic diagnosticsHistology typeControl ultrasound
An ultrasound system (100) for imaging a volumetric region comprising a region of interest (12) comprising: a probe having an array of CMUT transducers (14) adapted to transmit ultrasound beams and receive returning echo signals over the volumetric region; a beamformer (64) coupled to the array and adapted to control ultrasound beam transmission and provide ultrasound image data of the volumetric region; a transducer controller (62) coupled to the beamformer and adapted to vary driving pulse characteristics of the CMUT transducers, a region of interest identifier (72) enabling an identification of a region of interest on the basis of the ultrasound image data; a beam path analyzer (70) responsive to the ROI identification and arranged to detect an attenuating tissue type in between the probe and the ROI based on a depth variation in attenuation of the received signal; wherein the transducer controller is further adapted to change, based on the attenuating tissue type detection, at least one parameter of the driving pulse characteristics.
Owner:KONINKLJIJKE PHILIPS NV
Analysis of fragmentation patterns of cell-free DNA
Factors affecting the fragmentation pattern of cell-free DNA (e.g., plasma DNA) and the applications, including those in molecular diagnostics, of the analysis of cell-free DNA fragmentation patterns are described. Various applications can use a property of a fragmentation pattern to determine a proportional contribution of a particular tissue type, to determine a genotype of a particular tissue type (e.g., fetal tissue in a maternal sample or tumor tissue in a sample from a cancer patient), and / or to identify preferred ending positions for a particular tissue type, which may then be used to determine a proportional contribution of a particular tissue type.
Owner:THE CHINESE UNIVERSITY OF HONG KONG
Neural netork based identification of areas of interest in digital pathology images
PendingUS20220076411A1Toxic reactionQuick and reliableMedical communicationImage enhancementData compressionData set
A CNN is applied to a histological image to identify areas of interest. The CNN classifies pixels according to relevance classes including one or more classes indicating levels of interest and at least one class indicating lack of interest. The CNN is trained on a training data set including data which has recorded how pathologists have interacted with visualizations of histological images. In the trained CNN, the interest-based pixel classification is used to generate a segmentation mask that defines areas of interest. The mask can be used to indicate where in an image clinically relevant features may be located. Further, it can be used to guide variable data compression of the histological image. Moreover, it can be used to control loading of image data in either a client-server model or within a memory cache policy. Furthermore, a histological image of a tissue sample of a tissue type that has been treated with a test compound is image processed in order to detect areas where toxic reactions to the test compound may have occurred. An autoencoder is trained with a training data set comprising histological images of tissue samples which are of the given tissue type, but which have not been treated with the test compound. The trained autoencoder is applied to detect tissue areas by their deviation from the normal variation seen in that tissue type as learnt by the training process, and so build up a toxicity map of the image. The toxicity map can then be used to direct a toxicological pathologist to examine the areas identified by the autoencoder as lying outside the normal range of heterogeneity for the tissue type. This makes the pathologists review quicker and more reliable. The toxicity map can also be overlayed with the segmentation mask indicating areas of interest. When an area of interest and an area identified as lying outside the normal range of heterogeneity for the tissue type, and increased confidence score is applied to the overlapping area.
Owner:LEICA BIOSYST IMAGING
Microtome and method for operating a microtome
InactiveUS20170115189A1High level of functionalityInherent safetyWithdrawing sample devicesMagnetic tension forceHistology type
In a microtome (1) for producing thin sections for histology, there is a danger of collisions between the sample (9) and the cutting edge (7) in setup mode for coarse feed. It is an object of the invention to limit the collision force of such a collision so that it lies within an admissible range and, therefore, damage is avoided, and the microtome (1) is thereby inherently safe in setup mode. It is also an object of the invention, using the same means, to make available methods that resolve collisions and permit automatic approximation between sample (9) and cutting edge (7). The support force of the associated advancing means (18) acting in the advancing device (12) is limited since the otherwise customary screwing of the associated advancing means (18) on the advancing device (12) is replaced, for example, by a spring mounting or by a connection acting with magnetic force. Thus, when the support force is exceeded in the event of a collision, the associated advancing means (18) lift away from their contact face and experience a displacement (30). The collision force is thus limited to the support force. An additional switching off of the electromotive advancing drive and an associated process for resolving a collision via the electrical control (11) forms the basis of a further method for automatic approximation between sample (9) and cutting edge (7), which is likewise inherently safe by using the same means. The microtome (1) according
Owner:HEID HANS LUDWIG
Methods and compositions for elucidating protein expression profiles in cells
InactiveUS20060134629A1VirusesMicrobiological testing/measurementProtein expression profileTissues types
The present invention relates generally to methods and compositions for the identification of differential protein expression patterns and concomitantly the active genetic regions that are directly or indirectly involved in different tissue types, disease states, or other cellular differences desirable for diagnosis or for targets for drug therapy.
Owner:LINK CHARLES +9
Cell-free DNA methylation patterns for disease and condition analysis
ActiveUS20200131582A1The result is accurateLow sequencing coverageMicrobiological testing/measurementBiostatisticsDiseaseCell free
Disclosed herein are methods and systems of utilizing sequencing reads for detecting and quantifying the presence of a tissue type or a disease type in cell-free DNA prepared from blood samples.
Owner:UNIV OF SOUTHERN CALIFORNIA +1
System and method for providing assessment of tumor and other biological components contained in tissue biopsy samples
ActiveUS20160367228A1Surgical needlesDiagnostics using spectroscopyAbnormal tissue growthTissue biopsy
An exemplary system, method and computer-accessible medium can include, for example, receiving information related to a scan(s) of a three-dimensional structure(s) containing a first tissue(s) and a second tissue(s), and providing the information to a system for identifying respective tissue types of the first tissue(s) and the second tissue(s). The structure(s) can be scanned to generate the information. The structure(s) can include a paraffin block(s). The first tissue(s) or the second tissue(s) can be excised. The tissue types can include a cancerous tissue and a non-cancerous tissue, and the first tissue(s) can be identified as the cancerous tissue and the second tissue(s) can be identified as the non-cancerous tissue.
Owner:MEMORIAL SLOAN KETTERING CANCER CENT
System and method of characterizing vascular tissue
A system and method is provided for using backscattered data and known parameters to characterize vascular tissue. Specifically, in one embodiment of the present invention, an ultrasonic device is used to acquire RF backscattered data (i.e., IVUS data) from a blood vessel. The IVUS data is then transmitted to a computing device and used to create an IVUS image. The blood vessel is then cross-sectioned and used to identify its tissue type and to create a corresponding image (i.e., histology image). A region of interest (ROI), preferably corresponding to the identified tissue type, is then identified on the histology image. The computing device, or more particularly, a characterization application operating thereon, is then adapted to identify a corresponding region on the IVUS image. To accurately match the ROI, however, it may be necessary to warp or morph the histology image to substantially fit the contour of the IVUS image. After the corresponding region is identified, the IVUS data that corresponds to this region is identified. Signal processing is then performed and at least one parameter is identified. The identified parameter and the tissue type (e.g., characterization data) is stored in a database. In another embodiment of the present invention, the characterization application is adapted to receive IVUS data, determine parameters related thereto (either directly or indirectly), and use the parameters stored in the database to identify a tissue type or a characterization thereof.
Owner:THE CLEVELAND CLINIC FOUND
Neural network based identification of areas of interest in digital pathology images
A CNN is applied to a histological image to identify areas of interest. The CNN classifies pixels according to relevance classes including one or more classes indicating levels of interest and at least one class indicating lack of interest. The CNN is trained on a training data set including data which has recorded how pathologists have interacted with visualizations of histological images. In the trained CNN, the interest-based pixel classification is used to generate a segmentation mask that defines areas of interest. The mask can be used to indicate where in an image clinically relevant features may be located. Further, it can be used to guide variable data compression of the histological image. Moreover, it can be used to control loading of image data in either a client-server model or within a memory cache policy. Furthermore, a histological image of a tissue sample of a tissue type that has been treated with a test compound is image processed in order to detect areas where toxic reactions to the test compound may have occurred. An autoencoder is trained with a training data set comprising histological images of tissue samples which are of the given tissue type, but which have not been treated with the test compound. The trained autoencoder is applied to detect tissue areas by their deviation from the normal variation seen in that tissue type as learnt by the training process, and so build up a toxicity map of the image. The toxicity map can then be used to direct a toxicological pathologist to examine the areas identified by the autoencoder as lying outside the normal range of heterogeneity for the tissue type. This makes the pathologist's review quicker and more reliable. The toxicity map can also be overlayed with the segmentation mask indicating areas of interest. When an area of interest and an area identified as lying outside the normal range of heterogeneity for the tissue type, and increased confidence score is applied to the overlapping area.
Owner:LEICA BIOSYST IMAGING
Systems and methods for in-operating-theatre imaging of fresh tissue resected during surgery for pathology assessment
ActiveUS20160313252A1Time necessaryFacilitates in-operating-theater analysisMaterial analysis by observing effect on chemical indicatorMicroscopesFresh TissueOperating theatres
The disclosed technology brings histopathology into the operating theatre, to enable real-time intra-operative digital pathology. The disclosed technology utilizes confocal imaging devices image, in the operating theatre, “optical slices” of fresh tissue—without the need to physically slice and otherwise process the resected tissue as required by frozen section analysis (FSA). The disclosed technology, in certain embodiments, includes a simple, operating-table-side digital histology scanner, with the capability of rapidly scanning all outer margins of a tissue sample (e.g., resection lump, removed tissue mass). Using point-scanning microscopy technology, the disclosed technology, in certain embodiments, precisely scans a thin “optical section” of the resected tissue, and sends the digital image to a pathologist rather than the real tissue, thereby providing the pathologist with the opportunity to analyze the tissue intra-operatively. Thus, the disclosed technology provides digital images with similar information content as FSA, but faster and without destroying the tissue sample itself.
Owner:SAMANTREE MEDICAL SA
Method and assembly for correcting a relaxation map for medical imaging applications
InactiveUS8655038B2Accurate estimateReducing certain artefact and noiseCharacter and pattern recognitionMeasurements using NMR imaging systemsDiagnostic Radiology ModalityVoxel
A method for correcting a relaxation map of an object scanned with a magnetic resonance imaging modality the object having a plurality of structure and / or tissue types. The method includes deriving a first relaxation map of a scanned object from at least two three-dimensional scans of the object acquired using a sequence of ultrashort echo time pulses adapted for distinguishing between the various types of a plurality of structure and / or tissue types of the object. Information is obtained on the type of structure and / or tissue type present in voxels in the first relaxation map and binarizing the obtained information. A corrected relaxation map is generated by combining the binarized information with the first relaxation map.
Owner:IMINDS +1
System and method of characterizing vascular tissue
Owner:THE CLEVELAND CLINIC FOUND
System for automatic tumor detection and classification
Certain aspects of the present disclosure provide techniques for automatically detecting and classifying tumor regions in a tissue slide. The method generally includes obtaining a digitized tissue slide from a tissue slide database and determining, based on output from a tissue classification module, a type of tissue of shown in the digitized tissue slide. The method further includes determining, based on output from a tumor classification model for the type of tissue, a region of interest (ROI) of the digitized tissue slide and generating a classified slide showing the ROI of the digitized tissue slide and an estimated diameter of the ROI. The method further includes displaying on an image display unit, the classified slide and user interface (UI) elements enabling a pathologist to enter input related to the classified slide.
Owner:APPLIED MATERIALS INC
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