The invention relates to the technical field of polytetrafluoroethylene processing, in particular to a rapid prototyping device and working method for polytetrafluoroethylene sheets, including a workbench and a blanking table, as well as a controller, a feeding mechanism, a forming mechanism and a conveying mechanism. The controller is fixed on one side of the top of the workbench, the feeding mechanism includes a discharge assembly and a push assembly, the discharge assembly is fixed on the top of the workbench and is located beside the controller, and the push assembly is fixed On the workbench and directly below the discharging assembly, the forming mechanism includes a carrying frame, a mold table assembly, a cooling assembly, a shifting and cutting assembly and a limit assembly, and the conveying mechanism includes a clamping assembly and a retrieving assembly. The present invention By adding PTFE raw materials to the lower hopper and manipulating the controller, rapid prototyping of PTFE sheets can be performed, which is safe, efficient, precise and controllable, and greatly improves the forming efficiency of PTFE sheets.