A space motion mixer comprises a crank arm, a rocking bar, a container frame, a mixing container, a machine frame, a speed reduction gearing, a motor, etc. The mixing container with a helical line-shape scraping blade therein is arranged inside the container frame, two ends of the container frame are mechanically connected to the crank arm via a ball pair and the rocking bar via a universal joint respectively, and the crank arm and the rocking bar are respectively connected with a rotary pair and the machine frame. When the crank arm rotates in a complete alternation, the rocking bar swings around the machine frame, and the mixing container has a space motion containing rotation and movement; because of the space quick return motion and helical curve scraping blade, the materials in the container can generate a three-D projecting motion along axial, radial and circumferential directions for driving materials to be in a conglomeration and diffusion motion alternately for thorough mixing to have a good mixing effect and a high mixing efficiency, additionally, the invention is provided with simple structure, and can be controlled conveniently and manufactured easily.