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116results about How to "Functional impairment" patented technology

Indwelling catheter

An indwelling catheter comprises a tube, a female connector and an elastically deformable hemostasis valve which can be pressed by a male connector. An opening taper portion tapered forwardly is formed in a longitudinal intermediate portion of an inner circumferential surface of the female connector. The elastically deformable hemostasis valve is provided longitudinally slidably in the opening taper portion of the female connector and an inside portion extending rearwardly from the opening taper portion. The hemostasis valve includes; a body having a hollow form opened at its front and rear ends or a tubular portion fitted over the connecting portion from a rearward direction; and an openable / closable portion being opened by elastic deformation of the body or the tubular portion.
Owner:NIPRO CORP

Methods of determining whether a pregnant woman is at risk of developing preeclampsia

The present invention provides methods and compositions related to biomarker profiles for each trimester of pregnancy. The present invention also provides methods for identifying patients at risk of developing a complication of pregnancy, such as preeclampsia. In further embodiments, the present invention relates to methods for the diagnosis of patients with preeclampsia.
Owner:UNITED STATES OF AMERICA +1

Trailer towing device for a tractor vehicle

A trailer towing device for a tractor vehicle (1) which comprises a coupling ball (11), having a hollow space (21) for coupling a trailer vehicle (2), and a ball support (17) which engages with an end area in the hollow space (21) through an opening (22) provided in the coupling ball (11) and supports the coupling ball (11), such that the end area of the ball support (17) comprises a joint ball (15) on which the coupling ball (11) is fitted and can rotate so that, together with the coupling ball (11), the joint ball forms a ball joint (28).
Owner:ZF FRIEDRICHSHAFEN AG

Combination therapy for depression, prevention of suicide, and various medical and psychiatric conditions

The present invention relates to a new method of treatment for persons meeting diagnoses for major depressive disorder, or other unipolar (non-bipolar, non-psychotic and non-treatment resistant) depression. The method comprises administering a combination of two categories of drugs, antipsychotics or dopamine system stabilizers, in combination with a newer antidepressant such as a selective serotonin reuptake inhibitor, as initial treatment or as soon as possible. The method targets the prevention of suicide, and provides other benefits including preventing disease progression development of tolerance toward the antidepressants. Another aspect of the invention relates to using the method for alleviating cognitive distortion and related functional impairment or health risks, and / or using the method for smoking cessation or nicotine withdrawal.
Owner:MIGALY PETER

Therapeutic treatment of human cancers using simple salts of zinc

The present invention is a non-topical method of therapeutically treating human cancer patients which comprises an administration of an anti-cancer medicament comprising at least one simple organic or inorganic salt of zinc in at least a minimally effective concentration to suppress malignant tumor growth and induce tumor regression in-vivo. Administration can be performed by oral, parenteral, and / or body cavity routings; and the therapeutic treatment method is effective for the treatment of a diverse range of primary human cancers and metastatic diseases.
Owner:UGOLKOV ANDREY

Carotenoids, carotenoid analogs, or carotenoid derivatives for the treatment of proliferative disorders

InactiveUS20060276372A1Limit hepatic fibrosisLimit progression to cirrhosisBiocideHydrocarbon active ingredientsApoptosisBiology
A method and system used for treating proliferative disorders using carotenoids, carotenoid analogs, and / or carotenoid derivatives. The method and system may be used for chemoprevention and / or chemotherapy. The method and system may induce apoptosis in target cells, tissues, and / or organs. The analog, derivative, or intermediate may be administered to a cell, a group of cells, a tissue, an organ or a subject, such that at least a portion of the undesirable consequences of the proliferative disorder are thereby reduced.
Owner:CARDAX PHARMA

Treatment of carpal tunnel syndrome by injection of the flexor retinaculum

An apparatus and method for identifying the flexor retinaculum of the carpal tunnel, injecting an effective amount of an agent into at least a portion of flexor retinaculum or tissue adjacent thereto, wherein the agent is configured to weaken the flexor retinaculum. The system may further include means for increasing the tensile stress in the flexor retinaculum post-injection using hand exercises, thereby weakening its structural integrity and decreasing the pressure within the carpal tunnel that impairs median nerve function.
Owner:JOHN M AGEE & KAREN K AGEE TRUSTEES OF THE JOHN M AGEE TRUST

Methods for enhancing engraftment of purified hematopoietic stem cells in allogenic recipients

InactiveUS20070098693A1Facilitate HSC engraftmentEnhance engraftmentBiocidePeptide/protein ingredientsDendritic cellGraft versus host disease induction
CD8+ / TCR− bone marrow cells facilitate engraftment of hemapoietic stem cells (HSQ in allogeneic recipients without causing graft versus host disease. The present invention identifies the main subpopulation (55-65%) of CD8+ / TCR− facilitating cells (FQ as plasmacytoid precursor dendritic cells (p-preDC). The present invention notably demonstrates that FC and p-preDC share many phenotypic, morphological, functional features, including IFN-α production, activation and survival after stimulation, and expansion and maturation after FIO-Ligand (FL) treatment. FL mobilized FC, the majority of which express a pre-DC phenotype, facilitate HSC engraftment. Although p-preDC significantly enhance HSC engraftment, they do so with less efficiency than FC. The present invention for the first time defines a direct functional role for p-preDC in HSC engraftment and will have a significant impact on strategies to design effective facilitating cell-based therapies for transplantation.
Owner:UNIV OF LOUISVILLE RES FOUND INC

Nonaqueous secondary battery

To provide a novel structure of a separator in a secondary battery. A nonaquesous secondary battery includes a positive electrode, a negative electrode, an electrolyte solution, a first separator, and a second separator. The first separator and the second separator are provided between the positive electrode and the negative electrode. The first separator is provided with a first pore, the second separator is provided with a second pore, and the size of the first pore is different from the size of the second pore. Furthermore, the proportion of the volume of the first pores in the first separator is different from the proportion of the volume of the second pores in the second separator.
Owner:SEMICON ENERGY LAB CO LTD

Roof rack for a motor vehicle, and a method for operating a controller of a motor vehicle and a corresponding controller

A roof rack assembly for a motor vehicle includes roof rails having a recess and constructed to be fastened on a vehicle roof of the motor vehicle. A load carrier to be installed on the roof rails has a mounting projection engaging with the roof rails through the recess when the load carrier is installed and cooperating with a mounting receptacle for retaining the load carrier. The recess is closed by a cover when the load carrier is not installed, with a detection device detecting a cover state of the recess. A method for operating a controller of a motor vehicle and a corresponding controller are also described.
Owner:AUDI AG

Trailer towing device for a tractor vehicle

InactiveUS20130001924A1Compact structureDetect orientationTowing devicesEngineeringTractor trailer
A trailer towing device for a tractor vehicle (1) which comprises a coupling ball (11), having a hollow space (21) for coupling a trailer vehicle (2), and a ball support (17) which engages with an end area in the hollow space (21) through an opening (22) provided in the coupling ball (11) and supports the coupling ball (11), such that the end area of the ball support (17) comprises a joint ball (15) on which the coupling ball (11) is fitted and can rotate so that, together with the coupling ball (11), the joint ball forms a ball joint (28).
Owner:ZF FRIEDRICHSHAFEN AG

Handheld device cradle with a substantially semicircular clip assembly and an advertising method

A device cradle having a clip assembly for attaching the cradle to an external tube-shaped object. The cradle has an open receptacle sized and configured to removably hold a handheld electric device therein. The clip assembly has a substantially semicircular body with opposing first and second ends. The first end is pivotally connected to a flat surface of the cradle with the clip body. The second end is resiliently biased toward the flat cradle surface so as to form a substantially semicircular clipping aperture between the clip body and the flat cradle surface for releaseably and perpendicularly holding the external tube-shaped object therethrough.
Owner:SUN COAST MERCHANDISE

Fuel overflow valve for a fuel injection system, and fuel injection system having a fuel overflow valve

The invention relates to a fuel overflow valve for a fuel injection system, particularly for limiting the pressure in a low-pressure region of the fuel injection system. The fuel overflow valve has a valve housing, in which a valve member is disposed in a stroke-moving manner, the stroke movement of the valve member controlling a connection of an inlet to the valve housing to a release region. The valve member is loaded by a valve spring in the direction of a locking position in which the connection of the inlet to the release region is interrupted, and is loaded by the pressure present in the inlet in the opening direction. The valve member may carry out a further stroke in the locking direction beyond the locking position thereof, where the valve spring does not act upon the valve member. Due to the increased stroke of the valve member, an improved balance of pressure and volume fluctuations is enabled in the low pressure region and the stroke of the valve spring, and thus the stress thereof, may be kept low.
Owner:ROBERT BOSCH GMBH

Two-Component Rna Virus-Derived Plant Expression System

A process for replicating or for replicating and expressing a sequence of interest in a plant, comprising: (i) an RNA replicon or a precursor thereof, said RNA replicon being derived from a plus-sense single stranded RNA virus and comprising at least one sequence of interest; and (ii) a helper replicon, or a precursor thereof, wherein said helper replicon is (a) incapable of systemic movement in said plant both in the presence and in the absence of said RNA replicon (i) and (b) capable of expressing in a plant one or more proteins necessary for systemic movement of said RNA replicon (i), whereby said RNA replicon (i) is capable of replicating or replicating and expressing said sequence of interest in said plant, but unable to move systemically in said plant in the absence of said one or more proteins expressed by said helper replicon (ii).
Owner:ICON GENETICS

Component having a micromechanical microphone structure

Substrate-side overload protection for the diaphragm structure of a microphone component having a micromechanical microphone structure which impairs the damping properties of the microphone structure as little as possible, in which the microphone structure includes a diaphragm structure having at least one acoustically active diaphragm which is formed in a diaphragm layer above a semiconductor substrate. The diaphragm structure spans at least one sound opening in the rear side of the substrate. A stationary, acoustically permeable counter element is formed in the layer structure of the component above the diaphragm layer. According to the invention, at least projections are formed at the outer edge area of the diaphragm structure which protrude beyond the edge area of the sound opening, so that the edge area of the sound opening acts as a substrate-side stop for the diaphragm structure.
Owner:ROBERT BOSCH GMBH

Hydraulic actuating device for actuating a shift rod in particular of a gearbox for motor vehicles

There is disclosed a hydraulic actuating device for actuating a shift rod in particular of a gearbox for motor vehicles, which comprises a cylinder chamber provided in or on a gear housing for accommodating a shift piston which is actively connected to the shift rod and which divides the cylinder chamber into two working chambers which can selectively be acted upon by a pressure medium from a reservoir for the latter, said working chambers being separated from one another by means of a sealing arrangement arranged on the shift piston. The sealing arrangement is designed in a valve-like manner so that, when at least one working chamber is acted upon by pressure medium, it connects said working chamber to an auxiliary chamber which is delimited by the sealing arrangement and which in turn can be connected to the reservoir for the pressure medium. As a result, a cost-effective hydraulic actuating device is provided which is vented in a simple and efficient manner during operation from the working chambers via the auxiliary chamber to the reservoir.
Owner:FTE AUTOMOTIVE GMBH & CO KG

Misfueling Preventing Apparatus

Present disclosure is a misfueling preventing apparatus discriminating a fuel filler nozzle based on an outer diameter of the fuel filler nozzle. The misfueling preventing apparatus includes a base, a first link arm, a second link arm, a flapper and the stopper. The first link arm has a first trigger projection. The second link arm has a second trigger projection. If the fuel filler nozzle of light diesel oil pushes the first trigger projection and the second trigger projection, the first link arm and second link arm swing to a direction to which the first link arm and second link arm open to allow the flapper rotates to open.
Owner:ASTEER

Therapy device for edema and neuropathy

Disclosed is a therapy device for edema and neuropathy. Colored light within a visible light wavelength range, which is known to be useful for treating edema and neuropathy, is irradiated to a treatment area such as acupuncture points on a foot or a hand, or the surface of the skin, thereby relaxing the smooth muscle tissue of tissue cells with edema or neuropathy, facilitating peripheral vascular circulation and lymphatic circulation, and inducing the secretion of a material for treating edema and neuropathy.
Owner:COLOR SEVEN

Control device and method for operating a braking system equipped with an electric drive device and/or generator device

A control device for a braking system equipped with an electric drive device and / or generator device includes: a first receiving device with the aid of which a specified value regarding a brake pressure in at least one wheel brake cylinder of at least one brake circuit is receivable, a second receiving device with the aid of which an actual value regarding a pressure in the at least one brake circuit and / or the brake pressure in the at least one wheel brake cylinder is / are receivable, and a control unit with the aid of which a setpoint mode of the electric drive device and / or generator device is specifiable taking the received specified value and the received actual value into account.
Owner:ROBERT BOSCH GMBH

Electric power tool

In an electric power tool in which an electric motor is mounted in a housing that has a half-split structure, positions of middle screw fastening portions when a left housing and a right housing are fixed to each other by screws are located between a front protruding coil portion and a rear protruding coil portion. In other words, the protruding coil portions are located on either the front side or the rear side of the position of middle screw fastening portions when the left and right housings are fixed to each other by the screws. Accordingly, it is possible to effectively utilize a dead space that is likely to be formed between the front protruding coil portion and the rear protruding coil portion.
Owner:MAKITA CORP

Heat resistant ni-alloy material excellent in resistance to oxidation at high temperature

A composite resistive to high-temperature corrosion and abnormal oxidization, maintains original excellent high-temperature characteristics of Ni alloys over a long period of time, and suitable for applications in a high-temperature such as gas turbines, jet engines, and elements for exhaust-gas systems. A heat-resistant Ni-alloy composite has excellent high-temperature oxidation resistance, including a Ni-alloy substrate that has been subjected to an Al-diffusing treatment. The surface coat has a multi-layer structure including an inner layer composed of an α-Cr phase and an outer layer composed of a β phase (Ni—Al—Cr) and a γ′ phase (Ni3Al(Cr)) on the substrate surface. The Al content in the outer layer is at least 20 atomic percent. The α-Cr phase functions as a diffusion-barrier layer. The outer layer retains and secures a high Al content required for self-regeneration of a defective portion of the Al2O3 layer damaged in an operating condition.
Owner:NARITA TOSHIO

Method and device for producing subsurface markings in a transparent material body

A method and device for producing subsurface markings in a transparent material body by focusing a pulsed laser beam in the interior of the material body so that the laser beam exceeds the destruction threshold of the material body to produce a permanent marking. Individual markings form a freely selectable internal engraving as a result of a relative movement between the laser beam and the material body. The laser pulse is varied with respect to its pulse energy (P) by means of a discharge pulse (E) that has an adjustable time delay from an excitation pulse (A). Markings that have varying optical properties depending on the pulse energy (P) are produced in this fashion.
Owner:VITRO LASER TECH AG

Control device for a braking system of a vehicle, braking system, and method for operating a braking system for a vehicle

A control device for a braking system of a vehicle, with the aid of which at least one provided setpoint variable regarding a setpoint brake pressure to be set in a first brake circuit and at least one provided actual variable regarding an actual brake pressure that is present in the first brake circuit, and / or an elasticity variable regarding an elasticity of a second brake circuit of the braking system are receivable, and a default variable regarding a setpoint additional volume of a brake fluid of the second brake circuit which is in a main cylinder braking mode is establishable, by taking into account a first deviation variable of the at least one actual variable from the at least one setpoint variable, and / or a second deviation variable of the elasticity variable from a predefined setpoint elasticity variable, so that a control signal corresponding to the established default variable is outputtable to at least one volume conveying device. Moreover, also described is a method for operating a braking system for a vehicle.
Owner:ROBERT BOSCH GMBH

Osmium compounds for reduction of adverse inflammation

InactiveUS20050025805A1Reduce the possibilityReduction of the flux of nutrientsHeavy metal active ingredientsBiocideOsmium CompoundsCompound (substance)
Reduction of adverse inflammatory reaction to an implant or a transplant, or following trauma or infection, is achieved through catalysis of dismutation of the superoxide radical anion by an osmium containing compound. Treatment diseases caused by superoxide dismutase deficiency or mutation with superoxide radical anion dismutating osmium compounds or a carbonate radical anion decay catalyzing polymeric N-oxide is also disclosed.
Owner:ALPINE ELECTRONICS INC +1
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