The invention discloses a color-sensitive OLED module gamma tuning method. The color-sensitive OLED module gamma tuning method includes the steps of: adjusting white balance to determine the highest gray-scale brightness value and the lowest gray-scale brightness value, based on the highest gray-scale brightness value and the lowest gray-scale brightness value, determining the brightness Lv, the color coordinates x and y, and the target values of stimulus values X, Y and Z of each target tie point, conducting the gamma tuning for each target tie point until the brightness Lv, the color coordinates x and y, and the current values of stimulus values X, Y and Z of all target tie points are within the error range of the target value, finally, executing OTP burning, to backup the adjusted register values to IC of an OLED module. The adjusting efficiency is high, and the passing rates of gray-scale brightness and color coordinates are high. The color-sensitive OLED module gamma tuning method can effectively solve the problems of the occurrence of colored ribbon and coarse white strip phenomenon, the gray-scale gradient effect is good, the color-sensitive OLED module gamma tuning method is allowed to normalize the adjusted data in a graphical way and plot the curve, supports the manual debugging and reading of backup device, and is allowed to record the adjustment process and result in Excel form, thus being conducive to bulk data statistics.