The invention relates to the technical field of polyamide preparation, and discloses a preparation device of polyamide. The device comprises an injection molding machine, a screw rod and a drill bit,wherein the screw rod and the drill bit form a transmission device to extrude a polyamide liquid, a sleeve is arranged on the outer wall of the injection molding machine in a sleeve mode, a copper pipe is arranged in the sleeve, a threaded pipe is arranged in the copper pipe, the end part of the threaded pipe is connected with a supporting block, and an expansion body is arranged in the threaded pipe. The expansion body is automatically expanded according to the temperature of the injection molding machine, so that a cooling tube is opened, a cooling liquid is injected into the sleeve, the temperature of the injection molding machine is reduced, so that in the using process of the injection molding machine, the injection molding machine can be kept at a normal temperature all the time, theinjection molding machine can keep a good state in the injection molding process, the service life of a hydraulic element and an air cylinder in the injection molding machine is prolonged at the sametime, the abrasion degree of the drill bit and the injection molding machine can be reduced when the temperature of the injection molding machine is normal, so that the injection molding machine is always in a sealed state in the use process, the service life of the injection molding machine is prolonged, and the injection molding effect of the injection molding machine is improved.