16results about How to "Improve linear range" patented technology

A linear response stretchable resistance strain sensor belongs to the technical field of wearable sensors, is of a three-layer film structure and comprises a stretchable elastic substrate, a middle strain sensitive layer and a stretchable elastic package on the uppermost layer. The nano conductive material network bonded by the trace polymer not only has high conductivity close to that of a pure nano conductive material, but also enhances the mechanical stability of the conductive network. Uniform and random cracks are formed after primary stretching, and a stable structure similar to a plane spring is formed. The strain of the measured object drives the size of the air gap in the crack to change, and the conductive path is changed, so that the resistance is changed. The invention shows the detection capability of the sensor in a strain range of 0.001% to 100%, hysteresis (1.61%), linear response, fast enough reaction speed and extremely low residual resistance. The strain sensor also has stability, pressure insensitivity and waterproofness, and is suitable for long-term accurate monitoring of strain of soft systems such as biological tissues in the field of medical health.

The invention provides a serum amyloid A determination kit as well as preparation and application thereof, the kit optimizes and screens components and concentrations of buffer systems and inorganic salts in a reagent 1 and a reagent 2, particularly adds polyanions and DSS, and uses a quenching agent in the preparation process of anti-SAA antibody coated latex particles. According to the kit prepared by optimizing and screening the components, the specific recognition and binding capacity to the serum amyloid protein A is remarkably improved, the performance indexes such as the sensitivity, the linear range, the anti-interference capacity, the stability and the repeatability of the kit are improved, the linearity of a detection value in the linear range of 2mg / L to 500mg / L is good, the detection value is accurate and usable, and the kit is suitable for being used in the field of detection of the serum amyloid protein A. Therefore, the comprehensive performance of immunoassay on the serum amyloid protein A is improved.

The invention discloses a method for rapidly detecting hydrogen sulfide in a solution, which comprises the following steps: firstly, sufficiently reacting a nano AgI dispersion liquid with a solution to be detected under an acidic condition to obtain an iodide ion solution, then introducing a CsPbBr3 quantum dot solution into the iodide ion solution, standing for reaction, and determining the hydrogen sulfide in the solution according to fluorescence color change information of the solution after reaction or a right shift change value of a peak position of a fluorescence emission peak. The visual detection on the hydrogen sulfide content is realized. The CsPbBr3 quantum dot is used as a fluorescent probe and can directly react with iodide ions formed by conversion of hydrogen sulfide, conditions such as introduction of other trigger media and the like are not needed, obvious solution fluorescence emission peak appearance position change and fluorescence color change can be initiated, and efficient visual detection of the hydrogen sulfide content is realized; the method has the advantages of simplicity in operation, high sensitivity, rich color change and the like and is suitable for popularization and application.

A functionalized covalent organic framework fluorescent probe for identifying heavy metal Ba2+ and its application, wherein the structural formula is as follows: #imgabs0# wherein R2 is #imgabs1# The functionalized covalent organic framework fluorescent probe is effective in identifying heavy metal Ba 2+ The solvent system is acetonitrile and water in a volume ratio of 5:5. In the test water sample, a fluorescent probe is added, and its fluorescence emission intensity is measured at an excitation wavelength of λ=366nm. The fluorescence intensity at 490nm is significantly enhanced. The test water sample contains heavy metal Ba 2+ The functionalized covalent organic framework probe is Ba 2+ The detection limit was 1.67×10 ‑8 mol / L. The advantage is that the probe can be used in MeCN:H 2 Highly selective fluorescence “off-on” identification of heavy metal Ba in O system 2+ , has a good linear range, low detection limit and good sensitivity, and has been successfully used in the detection of heavy metal Ba in real life 2+ .

The present application belongs to the technical field of solid phase extraction, and particularly relates to a solid phase extraction membrane based on a defective MOF as well as a preparation method and application thereof. The solid phase extraction membrane based on the defective MOF comprises a carrier and a coating layer loaded on the surface of the carrier; the composition of the coating layer comprises a defective amino MOF material; the defective amino MOF material is prepared by taking a metal as a center, taking 3,5-dibromo-4-hydroxybenzaldehyde as a template molecule, and reacting with an amino organic ligand. By adopting a specific template molecule, the defective MOF structure has pores that are matched with the shape and size of the template molecule, has strong adsorption capacity for structural analogues of the template molecule, has strong selectivity for target analytes, can highly selectively enrich chlorophenol, and makes the solid phase extraction membrane have excellent adsorption effect on chlorophenol, high enrichment multiple and good reproducibility.

The invention discloses a method for identifying different processed products of fresh bamboo juice by detecting the mass concentration ratio of sugar components based on an HPLC-ELSD (High Performance Liquid Chromatography-Evaporative Light Scattering Detector) method and application. The method comprises the following steps: taking a processed fresh bamboo juice stock solution, and adding acetonitrile to prepare a fresh bamboo juice test solution; taking reference substances such as fructose, glucose and cane sugar, and adding acetonitrile to prepare a sugar mixed reference substance solution; injecting the fresh bamboo juice test solution into an HPLC-ELSD system, and detecting the content of sugar components; and calculating the mass concentration ratio of fructose to glucose to cane sugar, and identifying the processing technology of the fresh bamboo juice test solution according to the mass concentration ratio range of sugar components in the fresh bamboo juice stock solution obtained by different processing methods. According to the sugar content detection method, the variable spinning isomerism of glucose is eliminated, the analysis time is shortened to 15 minutes, the content difference of solid contents of different processed products can be eliminated by using the mass concentration ratio of sugar components, different processing technologies of the fresh bamboo juice can be quickly and effectively distinguished, and a support is provided for improving the quality standard of the fresh bamboo juice and guaranteeing the curative effect of the fresh bamboo juice.

The invention relates to a solid-phase microextraction probe as well as a preparation method and application thereof. The solid phase microextraction probe comprises a probe carrier and an extraction coating coated on the probe carrier, the extraction coating is a COF-DT material, and the COF-DT material is prepared by connecting 2, 5-dihydroxy terephthalaldehyde (Dha) and 1, 3, 5-tris (4-aminophenyl) benzene (Tab) through an imine bond. The probe disclosed by the invention shows excellent effect and repeatability in the aspect of adsorbing the neurotransmitter, and can be combined with ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS / MS) equipment for use, so that the analysis of the neurotransmitter in a wide concentration range is realized.

The invention belongs to the field of food detection. The invention provides an electrochemical sensor, a preparation method thereof and a method for detecting heavy metal ions in a compound seasoning by using the electrochemical sensor. An electrode material in the electrochemical sensor comprises a composite material obtained by coating an amino-functionalized alkaline MXene material with a nitrogen-doped carbon nanotube. The coordination of an MXene material and heavy metal ions is facilitated through alkalization and amino functionalization, the enrichment of the heavy metal ions is promoted, the electron transfer efficiency of the carbon nanotubes is improved through nitrogen doping, and active sites are provided for the heavy metal ions. The obtained composite material forms a three-dimensional stacked structure and a built-in electric field, provides a larger electrode surface area and stronger electron transfer capability, enhances the detection performance of the obtained electrochemical sensor, has a good linear range, lower detection limit and satisfactory anti-interference capability, repeatability, stability and recovery rate, and can be applied to the field of electrochemical sensors. A new strategy is provided for rapid detection of the heavy metal ions in the compound seasoning.

The application provides a method for improving the linear range of a latex-enhanced turbidimetry kit and the latex-enhanced turbidimetry kit, and relates to the technical field of analysis and detection. The application finds that sodium deoxycholate is added to reagent 1 of the existing latex-enhanced turbidimetry kit. Experimental verification shows that the correlation coefficient of the existing latex-enhanced turbidimetry kit can be effectively improved, and the upper limit of the detection linearity of the latex-enhanced turbidimetry kit is improved to 500 mg / L, thereby effectively alleviating the problem that the linear range of the reagent of the existing latex-enhanced turbidimetry kit is narrow, and 90% of the sample amount in the clinic cannot be covered, so as to affect the accuracy of the clinical detection result.

The invention discloses a method for rapidly detecting bromomethane, which comprises the following steps: firstly, adding a nucleophilic reagent into a bromomethane-containing base solution, and reacting under the condition of ultraviolet radiation to generate free bromide ions; and then introducing CsPbC13 quantum dots for reaction to obtain color change information of the obtained solution or right shift information of a 410-520nm fluorescence peak position of a solution system so as to realize visual detection of bromomethane. The introduced CsPbC13 quantum dots can directly react with bromide ions formed by conversion of bromomethane to induce change of color information of a fluorescent solution or a fluorescence peak position, and an intermediate response medium does not need to be additionally introduced; the corresponding mechanism of the peak position of the corresponding fluorescence emission peak and the fluorescence color is relatively stable, the sensitivity is high, and a new thought can be provided for high-sensitivity detection of bromomethane and other bromo-compounds; and the related detection method is simple, convenient to operate and suitable for popularization and application.

The invention belongs to the technical field of heavy metal ion detection, and particularly discloses a preparation method of an ionic liquid modified nanogold cluster material and application of the ionic liquid modified nanogold cluster material in detection of heavy metal ion cadmium. According to the invention, bovine serum albumin is taken as a stabilizing agent and a reducing agent, a nanogold cluster emitting red fluorescence is synthesized, and the ionic liquid modified nanogold cluster composite material is synthesized by utilizing electrostatic interaction between imidazolium ionic liquid and BSA (Bovine Serum Albumin). Due to the unique coordination effect between the cadmium ions and the imidazolium ionic liquid, the cadmium ions can effectively enhance the fluorescence intensity of the ionic liquid modified nanogold cluster composite material, the ionic liquid modified nanogold cluster composite material can be applied to detection of the cadmium ions in an actual sample, and a new thought is provided for convenient detection of the cadmium ions in a complex matrix.

The invention belongs to the field of electrochemical sensing detection, and particularly relates to a method for detecting the content of polypropylene in an aqueous solution based on electrochemiluminescence. According to the invention, a novel amphiphilic perylene derivative (PDI-NH2) electrochemical luminescence (ECL) sensor is firstly prepared and is used for ultra-sensitive detection and marking of polypropylene (PP) in an aqueous solution; pDI-NHH with positive charges can efficiently capture a trace amount of PP in an aqueous solution due to an inherent amphiphilic structure, so that ECL signal enhancement is realized. It is worthy of noting that the ECL sensor based on the PDI-NH2 luminophore has high stability and excellent sensitivity to polypropylene PP, the sensor has rapid response capacity to PP, the response time is as low as 12 s, and polypropylene can be efficiently recognized and detected in a complex environment. According to the method, the micro-plastic PP can be effectively identified and quantified without additional pretreatment and complex instruments, so that the method becomes an ideal tool for accurately quantifying the micro-plastic in the aqueous solution.

The invention belongs to the field of analytical chemistry, and particularly relates to molybdenum disulfide modulated iron monatomic bionic nano-enzyme as well as a preparation method and application thereof. The bionic nano-enzyme is in a hollow nano-rod shape, a carbon base anchored with iron monatomic atoms is uniformly doped with molybdenum disulfide lamellae, the iron monatomic atoms are anchored through nitrogen uniformly doped on the carbon base, the molybdenum disulfide lamellae are composed of 1T-phase molybdenum disulfide, a FeN5-MoS2 active center is formed, catalytic activity is achieved, and the carbon base and the molybdenum disulfide lamellae can be used for preparing the nano-enzyme. The heme b5-molybdenum cofactor is similar to the heme b5-molybdenum cofactor of natural sulfite oxidase, and has efficient peroxidase-like activity and good stability. Colorimetric signals are generated on the basis that the activity of iron atoms is affected by acetylcholine hydrolysate, a cascade detection platform with acetylcholin esterase as a marker is constructed, and sensitive detection of insecticide acetamiprid and distinguishing of different natural alkaloids are achieved. In order to adapt to convenient real-time detection in a complex environment, a paper-based colorimetric sensing platform is combined with a paper base, the residual content of acetamiprid is read through a mobile phone colorimetric program, and the method has the advantages of low cost, simplicity in operation, good specificity, high sensitivity and the like.

The invention relates to the technical field of medical detection, in particular to a urine trace protein detection reagent and application thereof. The invention discloses a reagent for detecting trace protein in urine. The reagent comprises a reagent R1 and a reagent R2, the reagent R1 is prepared from 0.05 mol / L to 0.15 mol / L of a buffer solution; 20 to 30 ml / L of polyethylene glycol; 2-4g / L of ammonium sulfate; 1-5 g / L of a polyelectrolyte; 0.5 to 1.5 g / L of preservative; 1-3 g / L of a surfactant; the reagent R2 comprises 1-3g / l of latex microspheres combined with a goat anti-human urine microalbumin antibody; the concentration of the buffer solution is 0.05 to 0.15 mol / L; 0.5 to 1.5 g / L of preservative; 1-3 g / L of a surfactant; and 0.5-1.5 g / L of a stabilizing agent. Under the condition that the detection sensitivity is guaranteed, the detection linear range is widened to the maximum extent, and the detection linear range can reach 0.01-1 g / L.

The invention belongs to the technical field of blood product detection methods, and particularly relates to an HPLC-ELSD (High Performance Liquid Chromatography-Evaporative Light Scattering Detector) determination method for residues in a human blood coagulation factor VIII. According to the scheme, an analysis method for detecting polysorbate 80 and polyethylene glycol 3350 in the human blood coagulation factor VIII by adopting a reversed-phase high-performance liquid chromatography in combination with an evaporative light-scattering detector is established. After the sample reconstitution fluid is subjected to high-speed centrifugation or filtration, supernate is taken and analyzed on a machine. Quantitative analysis results show that for polysorbate 80, the correlation coefficient is greater than 0.999 in the range of 10-500 mg / L; for polyethylene glycol 3350, the correlation coefficient is greater than 0.998 in the range of 50-2000mg / L. According to the method, the two residues can be rapidly and accurately detected, the technical problem that the accuracy of the detection result of the two residues is not ideal in the detection method of the human blood coagulation factor VIII in the prior art can be solved, and the method has wide popularization and application values.

The invention discloses a method for detecting insecticide in food and medicine. Copper nanoclusters BSA-CuNCs are used as fluorescent probes, and nano copper porphyrin DTAB-CuTPyP is used as a fluorescence quencher. When BSA-CuNCs and DTAB-CuTPyP are combined, DTAB-CuTPyP can induce aggregation of BSA-CuNCs, resulting in quenching of the fluorescence of BSA-CuNCs. After insecticide is added, the insecticide can be combined with DTAB-CuTPyP through electrostatic interaction, resulting in fluorescence recovery of BSA-CuNCs. The method provides a sensitive fluorescence platform for the determination of insecticide.