The invention discloses an ampoule bottle neck automatic opening system, which comprises a frame, an intermittent turntable, an ampoule bottle input device, an ampoule bottle label information detection device, an alcohol disinfection device, a grinding wheel assembly, a bottle neck breaking device, an ampoule bottle output device, The vertical shaft, motor and bottle neck collection box, ampoule input device, alcohol disinfection device, grinding wheel assembly, bottle neck breaking device and ampoule output device are distributed around the intermittent turntable; when the ampoule rotates to the breaking station, the bottle neck breaks The breaking device breaks the bottleneck of the ampoule bottle, and the broken neck falls into the bottleneck collection box through the bottleneck passing hole. Due to the adoption of the above-mentioned structure, this patent realizes the fully automatic operation of automatic feeding, disinfection, scratch cutting, breaking, and automatic output of ampoules, and can easily open a batch of ampoules automatically, greatly reducing the workload of medical staff Workload, easy to move and easy to operate and use. It has the characteristics of high degree of automation, streamlined operation, and small and compact structure.