The invention discloses precipitation-free, low-water-absorption, halogen-free and flame-retardant reinforced nylon 66 as well as a preparation method and application thereof. The reinforced nylon 66 comprises the following components: nylon 66 resin, a halogen-free flame retardant, a synergist, glass fibers, an anti-precipitation agent, a nucleating agent, a dispersing agent, a lubricating agent and an antioxidant. The preparation method comprises the following steps: adding the nylon 66 resin into a main material scale, adding the halogen-free flame retardant, the synergist, the anti-precipitation agent, the nucleating agent, the dispersant, the lubricant and the antioxidant into a mixer for mixing, adding an auxiliary material scale, adding the glass fibers into a side feeding metering scale, starting a double-screw extruder, sequentially starting a main material metering extruder and an auxiliary material metering extruder, performing discharging, starting a side feeding metering extruder, performing heating, melting, blending and extruding in the double-screw extruder, and performing cooling and granule cutting to obtain high-strength plastic. The reinforced nylon 66 has the advantages of high strength, high flame retardance, no precipitation, low water absorption, stable size, no toxicity and environment friendliness. The method is simple in process, low in cost and suitable for industrial production.