The invention discloses an ultrasonic energy control circuit for interventional therapy, which relates to the field of ultrasonic technology. The control circuit includes: a signal generator, a power amplifier, a matching network, an ultrasonic transducer and a feedback circuit connected in sequence, and the feedback circuit Connected with the signal generator, the signal generator is used to generate a sine wave, the power amplifier is used to amplify the signal of the sine wave, and the matching network is used to perform impedance and power analysis on the amplified sine wave. Matching, the ultrasonic transducer is used to transform the sine wave with impedance and power matching into electrical energy / mechanical energy, the feedback circuit is used to detect the power, frequency and impedance of the ultrasonic transducer, and convert the detected Power, frequency and impedance are sent to the signal generator. The invention realizes the automatic tracking and stabilization by setting the feedback circuit, so as to ensure the stability of the ultrasonic energy of the ultrasonic emitting device.