43results about How to "Overcome insoluble" patented technology

The invention relates to an application of a WAP (whey acidic protein) gene in transgenosis of a fruit fly. According to the application, the WAP gene in Fenneropenaeus chinensis is constructed in the fruit fly and is expressed in the fruit flies. The transgenic fruit fly prepared by utilizing the application has an antibacterial effect.

The invention discloses a genistein drop pill preparation and a preparation method thereof. The genistein dropping pill provided by the invention is prepared from the main drug genistein and a matrix. The weight ratio of genistein to substrate is preferably 1:2-6. The genistein dripping pill preparation provided by the invention has the advantages of high drug content, rapid drug release, rapid effect, stable quality, high bioavailability, convenient administration, low price, convenient production, carrying and storage, and the like.

The invention discloses a flue gas deep treatment method for simultaneous desulfurization and denitrification by an absorption method. The method uses a natural manganese oxide ore or a synthetic nanomanganese oxide which is added with a surfactant as an absorption liquid of NO<x> and SO2 to realize flue gas purification. According to the simultaneous desulfurization and denitrification method, the SO2 removal rate is maintained to be 95% or more, the NO removal rate is maintained to be 80% or more, reaction products can be separated and utilized, the operation cost is low, and the prospect is good.

The invention discloses a device and method for synchronous desulfurization and denitrification of flue gas. The method comprises the following steps: a porous filler is put in a box-shaped plate frame to be used as a gas-permeable absorption and reaction medium, a washing absorption liquid containing polyethylene glycol and manganese oxide is added into a flue gas pipeline by using a spraying mode, the washing absorption liquid forms a liquid film on the surface of the filler, and the manganese oxide in the washing absorption liquid converts NO and SO2 in the flue gas into a nitrate and a sulfate, respectively. After the flue gas is treated by the device and method for synchronous desulfurization and denitration provided by the invention, the SO2 removal rate is maintained at 95% or more,the NO removal rate is maintained at 80% or more, and the reaction product can be separated and utilized; and the equipment is simple, the operation costs are low, and the device and the method havevery good prospects.

The invention relates to the field of pharmaceutical preparation, and particularly relates to Bexarotene nano suspension. The Bexarotene nano suspension is characterized by being prepared by Bexarotene and a surfactant. Polyvinylpyrrolidone is used as the surfactant. The weight ratio of the Bexarotene to the surfactant is preferably 1: 1 to 1: 4. By adopting the Bexarotene nano suspension, the medicinal content can be increased, the quality stability is good, the toxicity and side effect is low, and the average granularity is about 100nm to 400nm.

The invention relates to a licorice flavonoid dispersible tablet and its preparation method and application, comprising licorice flavonoids and pharmaceutical excipients; the prescription of the dispersible tablet in parts by weight consists of the following components: 20-40 parts of licorice flavonoids, microcrystalline fiber 30-50 parts of vegetarian food, 5-10 parts of croscarmellose sodium, 3-8 parts of crospovidone, 2-3 parts of 5%-8% povidone solution, magnesium stearate 0.5‑1 part, 1‑3 part of phospholipid. The invention also provides a preparation method and application of the licorice flavone dispersible tablet. The licorice flavone dispersible tablet prepared by the preparation method provided by the invention has stable quality, fast drug release, improved bioavailability, and is suitable for preventing and treating gastric ulcer and duodenal ulcer.

The invention relates to a method for preparing a flame retardant bis[tri(chloroethoxy)silicon-acyloxy]ethane. The structure of the compound is represented by a formula shown in a drawing. The preparation method comprises the steps of reacting silicon tetrachloride with chloroethanol of a mole which is equal to that of silicon tetrachloride in an organic solvent at the temperature below 20 DEG C, then, dropwise adding glycol of a mole which is 0.5 times that of silicon tetrachloride, heating to the temperature of 50-70 DEG C after completing dripping, and reacting for 5-8 hours; then, dropwise adding chloroethanol of a mole which is 2-3 times that of silicon tetrachloride, and carrying out heat-preservation reaction for 6-9 hours at the temperature of 60-75 DEG C; adding an acid binding agent, and carrying out heat preservation for 1 hour while stirring; purifying, thereby obtaining the flame retardant bis[tri(chloroethoxy)silicon-acyloxy]ethane. The compound disclosed by the invention has high flame retarding efficacy due to the synergism of silicon and chlorine and is suitable for serving as a flame retardant for materials, such as polyvinyl chloride, polyurethane, epoxy resin, unsaturated resin and the like, and the preparation method is simple and is low in cost, so that the industrial production is easy to realize.

The invention relates to a fire retardant 2[3(3-bromine propoxy) silicon acyloxy] ethane compound and a preparation method thereof. The structure of the compound is shown as the following formula. The preparation method comprises the following steps: reacting silicon tetrachloride with 3-trimethylene bromohydrin of the same mole of the silicon tetrachloride in organic solvent at below 25 DEG C, then dropwise adding ethanediol 0.5 mole of silicon tetrachloride, rising temperature up to 55-75 DEG C, reacting for 6-10 hours; then dripping 3-trimethylene bromohydrin 2-3 mole of silicon tetrachloride, thermal reacting for 7-10 hours at 65-85 DEG C; then adding acid-binding agent, stirring and performing heat preservation for 1 hour; purifying so as to obtain the fire retardant 2[3(3-bromine propoxy) silicon acyloxy] ethane. The compound has high antiflaming efficiency, is applicable to fire retardants made of materials such as polyvinyl chloride, polyurethane, epoxy resin and unsaturated resin, is simple to prepare, has low cost, and is easy to realize industrial production.

The invention relates to a flame retardant ethylenedioxy dual-silicate propyl bromide compound and a preparation method thereof. The compound has the structure shown as the formula specified in the specification, wherein-OC3H6Br is 2-bromo-1-propoxy or 1-bromo-2-propoxy or a mixture of the 2-bromo-1-propoxy and the 1-bromo-2-propoxy. The preparation method comprises the following steps: dropwise adding bromopropanol into an organic solution of silicon tetrachloride at a temperature being below 25 DEG C, and reacting for 2 hours at 45 DEG C, wherein the molar mass of the bromopropanol is equal to that of the silicon tetrachloride; dropwise adding ethylene glycol and reacting for 6-10 hours at 55-75 DEG C, wherein the molar mass of the ethylene glycol is 0.5 time that of the silicon tetrachloride; cooling to the temperature being below 40 DEG C, dropwise adding the bromopropanol, and reacting for 6-10 hours at 65-85 DEG C, wherein the bromopropanol is 2-3 times that of the silicon tetrachloride; adding a small amount of acid binding agent, preserving heat and stirring for 1 hour; performing purification to obtain the flame retardant ethylenedioxy dual-silicate propyl bromide. The compound disclosed by the invention is suitable to be as the flame retardants of the materials such as polyvinyl chloride, polyurethane, epoxy resin and unsaturated resin, is simple in preparation process and low in cost, and can be put into industrial production easily.

The invention discloses a spinosad soluble concentrate which comprises the components in percentage by mass: 1% to 5% of a spinosad active compound, 70% to 88% of a solvent, 10% to 20% of a penetrating agent and 1% to 5% of an auxiliary agent. The invention also discloses a preparation method of the spinosad soluble concentrate, wherein the preparation method comprises the steps: heating an ethanol solvent to 30 DEG C-35 DEG C, adding the spinosad active compound while stirring, heating to 40 DEG C-50 DEG C, adding N-N-dimethylformamide and methanol while stirring, cooling to 40 DEG C or less, adding the penetrating agent, stirring until the solution becomes a homogeneous transparent liquid, and thus obtaining the spinosad soluble concentrate. The problem that spinosad is difficult to dissolve in water and organic solvents is solved, the spinosad soluble concentrate is prepared, the use range of spinosad is expanded, and the use method of spinosad is simplified.

The invention relates to an application of a nilaparvata lugens CYP6ER1 gene to gene modification of fruit flies. The nilaparvata lugens CYP6ER1 gene is constructed in the fruit flies, a GAL4/UAS binary expression system of the fruit flies is utilized, the CYP6ER1 gene can be excessively expressed in the fruit flies, the fruit flies can be used for determining whether the CYP6ER1 gene has the effects of removing toxicity and promoting metabolism on frequently-used pesticides controlling nilaparvata lugens to define whether the CYP6ER1 gene mediates resistance of the nilaparvata lugens to the pesticides, and besides, the fruit flies can be used for screening and developing novel pesticides.