43results about How to "Overcome insoluble" patented technology

The invention relates to a flame retardant bis[tris(1,3-dichloro-2-propoxy)silicon-acyloxy]ethane compound and a preparation method thereof. The structure of the compound is represented by a formula shown in a drawing. The preparation method comprises the steps of reacting silicon tetrachloride with 1,3-dichloro-2-propanol of a mole which is equal to that of silicon tetrachloride in an organic solvent at the temperature below 25 DEG C, then, dropwise adding glycol of a mole which is 0.5 times that of silicon tetrachloride, heating to the temperature of 65-80 DEG C after completing dripping, and reacting for 7-10 hours; then, dropwise adding 1,3-dichloro-2-propanol of a mole which is 2-3 times that of silicon tetrachloride, and carrying out heat-preservation reaction for 6-10 hours at the temperature of 70-90 DEG C; then, adding an acid binding agent, and carrying out heat preservation for 1 hour while stirring; purifying, thereby obtaining the flame retardant bis[tris(1,3-dichloro-2-propoxy)silicon-acyloxy]ethane. The compound disclosed by the invention has high flame retarding efficacy due to the synergism of silicon and chlorine and is suitable for serving as a flame retardant for materials, such as polyvinyl chloride, polyurethane, epoxy resin, unsaturated resin and the like, and the preparation method is simple and is low in cost, so that the industrial production is facilitated.

The invention relates to a fire retardant 2[3(chlorine propoxy)silicon acyloxy] ethane compound and a preparation method thereof. The structure of the compound is shown in the specification; -OC3H6Cl in the formula is 2-chlorin-1-propoxy or 1-chlorin-2-propoxy or a mixture of the 2-chlorin-1-propoxy and the 1-chlorin-2-propoxy. The preparation method comprises the following steps: dropwise adding equimolar chloropropanol to an organic solvent of silicon tetrachloride below 20 DEG C to react for 2 hours at 40 DEG C; then dropwise adding ethylene glycol which is 0.5fold mole of the silicon tetrachloride to react for 6-9 hours at 55-75 DEG C; cooling to below 40 DEG C; dropwise adding chloropropanol which is 2-3fold mole of the silicon tetrachloride to react for 6-10 hours at 65-85 DEG C; adding a little of acid-binding agent, and stirring for 1 hour in heat preservation, thereby obtaining fire retardant 2[3(chlorine propoxy)silicon acyloxy] ethane by purification treatment. The compound disclosed by the invention is applicable to being used as a fire retardant of the materials such as polyvinyl chloride, polyurethane, epoxy resin and unsaturated polyester resin, and is simple in preparation technology and low in cost, and easily achieves industrial production.

The invention belongs to the field of preparation of chitosan microspheres, in particular to a norisoboldine chitosan microsphere and a preparation method thereof. Specifically, it includes the following steps: 1) first dissolving norisoboldine in acetic acid solution, then adding chitosan to swell and then ultrasonically degassing, to prepare norisoboldine chitosan acetic acid solution; 2) in the round bottom Add liquid paraffin and emulsifier to the flask, add the norisoboldine chitosan acetic acid solution prepared in step 1) dropwise with stirring, and stir and emulsify at 40 °C for 0.5 h; 3) add crosslinking agent dropwise to prepare Get norisoboldine chitosan microspheres. Norisoboldine is prepared into chitosan microspheres, and the encapsulation rate of norisoboldine reaches 69.27%, which can improve the bioavailability of norisoboldine in vivo and reduce the frequency of clinical administration. Reduce dosage and reduce adverse reactions. The preparation method of the norisoboldine chitosan microspheres is simple in operation, easy to repeat, and has good controllability, and has a good application prospect.

The invention discloses a fatty group polyamidoimide, a preparation method and an application, which belongs to the technical field of preparation of high molecular compound. The structural formula is shown in a formula 1, formula 1, the fatty group polyamidoimide prepared by the invention has the advantage of good solubility, and enables a complete solution in an organic solvent NMP, DMF, DMAc or DMSO after being heated to the temperature of 60 DEG C, wherein the solubility is 6g / 100 mL, and the insufficient aspects of indissoluble and difficult processing of aromatic PAI can be overcomed. According to the invention, the obtained fatty group polyamidoimide is hydrolyzed to obtain a polymer containing carboxyl capable of effectively chelating metallic lead ions in water, wherein the adsorption quantity can reach to 580.2 mgPb 2<+> / g.

The invention relates to the field of pharmaceutical preparation, and particularly relates to Bexarotene nano suspension. The Bexarotene nano suspension is characterized by being prepared by Bexarotene and a surfactant. Polyvinylpyrrolidone is used as the surfactant. The weight ratio of the Bexarotene to the surfactant is preferably 1: 1 to 1: 4. By adopting the Bexarotene nano suspension, the medicinal content can be increased, the quality stability is good, the toxicity and side effect is low, and the average granularity is about 100nm to 400nm.

The invention discloses a gambogic acid nano-suspension, which is prepared from gambogic acid and a surfactant, and the surfactant is poloxamer 188. The preparation method is as follows: 1) Weigh gambogic acid crude drug and dissolve it with absolute ethanol to obtain an organic phase; 2) Dissolve a surfactant in pure water to obtain an aqueous phase; 3) Under conditions of ice-water bath and stirring, the Add the dehydrated ethanol solution of gambogic acid to the water phase, stir magnetically, so that the gambogic acid is evenly dispersed in the aqueous solution of the surfactant, and the ethanol is removed by rotary evaporation to obtain a coarse suspension; 4) the coarse suspension is sequentially Perform high-speed shearing treatment and high-pressure homogenization treatment to obtain gambogic acid nano-suspension. The preparation of the gambogic acid nano-suspension in the present invention can improve the solubility of the drug, improve the safety of the drug, change the distribution of the drug in the body, reduce the dosage of the drug, reduce the toxic and side effects, improve the safety and compliance, and play a better role in the treatment. Effect.

The invention relates to a flame retardant ethylenedioxy dual-silicate propyl chloride and a preparation method thereof. The compound has a structure shown in the specification, wherein m is an integer from 0 to 3. The preparation method comprises the following steps: dropwise adding propylene epoxide into an organic solution of the silicon tetrachloride at a temperature being below 0 DEG C and reacting for 1 hour at 40 DEG C, wherein the molar mass of the propylene epoxide is 2 times that of the silicon tetrachloride; dropwise adding ethylene glycol and reacting for 6-9 hours at 55-75 DEG C, wherein the molar mass of the ethylene glycol is 0.5 time that of the silicon tetrachloride; cooling to the temperature being below 30 DEG C, dropwise adding the propylene epoxide and reacting for 4-7 hours at 60-80 DEG C, wherein the molar mass of the propylene epoxide is 1-1.5 times that of the silicon tetrachloride; performing purification treatment to obtain the flame retardant ethylenedioxy dual-silicate propyl chloride. The compound disclosed by the invention has high synergistic flame retardant performance of double elements of silicon and chloride, is suitable to be used as flame retardants of the materials such as polyvinyl chloride, polyurethane, epoxy resin and unsaturated resin, is simple in preparation process and low in cost, and can be put into industrial production easily.

The invention relates to a flame retardant bis[tris(3-chloropropoxy)silicon-acyloxy]ethane compound and a preparation method thereof. The structure of the compound is represented by a formula shown in a drawing. The preparation method comprises the steps of reacting silicon tetrachloride with 3-chloropropanol of a mole which is equal to that of silicon tetrachloride in an organic solvent at the temperature below 20 DEG C, then, dropwise adding glycol of a mole which is 0.5 times that of silicon tetrachloride, heating to the temperature of 55-75 DEG C after completing dripping, and reacting for 5-9 hours; then, dropwise adding 3-chloropropanol of a mole which is 2-3 times that of silicon tetrachloride, and carrying out heat-preservation reaction for 6-9 hours at the temperature of 65-85 DEG C; adding an acid binding agent after HCl gas is completely discharged, and carrying out heat preservation for 1 hour while stirring; purifying, thereby obtaining the flame retardant bis[tris(3-chloropropoxy)silicon-acyloxy]ethane. The compound disclosed by the invention has high flame retarding efficacy due to the synergism of silicon and chlorine elements and is suitable for serving as a flame retardant for materials, such as polyvinyl chloride, polyurethane, epoxy resin, unsaturated resin and the like, and the preparation method is simple and is low in cost, so that the industrial production is easy to realize.

The invention relates to a fire retardant 2[3(3-bromine propoxy) silicon acyloxy] ethane compound and a preparation method thereof. The structure of the compound is shown as the following formula. The preparation method comprises the following steps: reacting silicon tetrachloride with 3-trimethylene bromohydrin of the same mole of the silicon tetrachloride in organic solvent at below 25 DEG C, then dropwise adding ethanediol 0.5 mole of silicon tetrachloride, rising temperature up to 55-75 DEG C, reacting for 6-10 hours; then dripping 3-trimethylene bromohydrin 2-3 mole of silicon tetrachloride, thermal reacting for 7-10 hours at 65-85 DEG C; then adding acid-binding agent, stirring and performing heat preservation for 1 hour; purifying so as to obtain the fire retardant 2[3(3-bromine propoxy) silicon acyloxy] ethane. The compound has high antiflaming efficiency, is applicable to fire retardants made of materials such as polyvinyl chloride, polyurethane, epoxy resin and unsaturated resin, is simple to prepare, has low cost, and is easy to realize industrial production.

The invention discloses a device and method for synchronous desulfurization and denitrification of flue gas. The porous filler is packed in a box-shaped plate frame as a gas-permeable absorption and reaction medium, and the washing and absorption liquid containing polyethylene glycol and manganese oxide is sprayed. Added to the flue gas pipeline, the washing and absorbing liquid forms a liquid film on the surface of the filler, and the manganese oxide in it converts NO and SO in the flue gas 2 For nitrates and sulfates. Through the device and method for synchronous desulfurization and denitrification of the present invention, SO 2 The removal rate is maintained above 95%, the NO removal rate is maintained above 80%, the reaction product can be separated and utilized, and the equipment is simple and the operation cost is low, so it has a good prospect.

The invention relates to a preparation method of microwave instant fillets, which belongs to the technical field of processing of aquatic products. A tumbler is adopted in a deodorization step; and deodorization accessories comprise ice water accounting for 20%-50% of the fillets in weight, starch accounting for 0.8%-1% of the fillets in weight, salt accounting for 0.6%-0.8% of the fillets in weight, white spirit accounting for 0.4%-0.6% of the fillets in weight and trehalose accounting for 0.3%-0.5% of the fillets in weight. Through optimizing the deodorization step, the preparation method is more complete and thorough; and the blending, flavoring, salting and deodorization steps in the prior art are differentiated, the deodorization is realized by the tumbler and the special deodorization accessories, and the independent deodorization procedure is formed, so that the fillets are deodorized more thoroughly and completely.