32results about How to "Overcome the disadvantage of prone to drug resistance" patented technology

The invention relates to a traditional Chinese medicine (TCM) oral liquid used for treating animal respiratory tract infection, which includes folium eriobotryae, aster, radix stemonae, fritillaria thunbergii, perilla leaves, bitter almond, ephedra herb, rhizoma pinellinae praeparata, tuckahoe, dried orange peel, asparagus, mustard seeds, radix glehniae, tussilago farfara, bitter orange, semen trichosanthis, radrx peucedani, liquorice and balloon flowers. The medicament is suitable for treating avian respiratory tract infection, such as infectious bronchitis, infectious laryngotracheitis and the like. The formulation of the medicament is combined with the special physiological structures that birds have short genital tract and can not digest lignified fibers to prepare the medicament into oral liquid which can rapidly disperse in feeding water, and then sicken beasts and birds take medicaments by drinking. The TCM oral liquid is convenient, easy to absorb and can achieve the purpose of rapid effect.

The invention relates to a premixing agent for treating livestock nematodiasis, comprising ivermectin, albendazol and auxiliary materials. The premixing agent is mainly used for preventing and treating livestock digestive canal nematodiasis and so on parasitic insect disease, has good preventing and treating actions for livestock digestive canal nematodiasis and ectozoa. The invention can treat the nematodiasis, meanwhile can prevent and treat the infection of the livestock parasite in vitro, can effectively improve the parasite-expelling effect, and has high safety.

The invention relates to a traditional Chinese medical oral liquid used for curing colibacillosis of poultries, which comprises four medicines of purslane, heartleaf houtluynia, Chinese pulsatilla and phellodendron. The combination of the four medicines has the effects of clearing away heat and toxic material, curing dysentery and improving the symptom of diarrhea caused by colon bacillus. Based on the fact that the specific physiological structure of poultries can not digest wood fibre owing to the short genital tracts, the medicaments are made into a dosage form of oral liquid which can be dispersed in drinking water and can be taken by sick poultries through drinking water, thereby being convenient for absorbing, and achieving the purpose of taking effect rapidly.

The invention provides a formula of medicine for preventing and curing coccidiosis of chicken, which comprises Chinese medicinal antibiotic medicament and Nicarbazinum, the Chinese medicament is in the form of compound powder preparation which comprises dichroa febrifuga 500-1000ppm, coptis root 500-100 ppm, green chiretta 500-1000ppm.

The invention relates to a traditional Chinese medical oral liquid used for curing respiratory tract infection of poultries and cattle, which comprises eleven medicaments of radix isatidis, forsythia, baikal skullcap root, Chinese ephedra, aster, almond, plaster, artificial bezoar, borneol, senso and liquorice. The medical oral liquid is suitable for curing respiratory tract infection of poultries and cattle, such as infective bronchitis, infectious laryngotracheitis, etc. Based on the fact that the specific physiological structure of poultries can not digest wood fibre owing to the short genital tracts, the medicaments are made into a dosage form of oral liquid which can be dispersed in drinking water and can be taken by sick poultries through drinking water, thereby being convenient for absorbing, and achieving the purpose of taking effect rapidly.

The invention discloses a compound weeding composition containing glufosinate-ammonium. The compound weeding composition comprises, by weight, 5 to 80% of active components consisting of glufosinate-ammonium and clomeprop in a weight ratio of 1: 20 to 20: 1, with the balance being auxiliary agents. The dosage form of the compound weeding composition may be a wettable powder, a water dispersible granule, a suspension concentrate, an oil concentrate, etc. The compound weeding composition can compensate for the defect that single glufosinate-ammonium has poor effect on cyperaceous drug-resistant weeds like Cyperus rotundus and the defect that single clomeprop can only control broadleaf weeds and cyperaceous weeds and almost has no effect on gramineous weeds, and is capable of effectively preventing and eliminating weeds; and the two above active components in a certain ratio range present synergistic effect and exert better effect compared with single glufosinate-ammonium and single clomeprop, so the dosage of pesticides is reduced, adverse impact of pesticides on ecological environment is lowered, and good prevention effect is exerted on gramineous weeds like Cyperus rotundus which is hard to prevent and eliminate with glufosinate-ammonium.

The invention relates to application of a coryebactrium parvum preparation (CPP) or a noncellular coryebactrium parvum preparation (NCP) in the field of pharmacy, in particular to application in preparing a medicament for treating novel A H1N1 influenza viruses. The coryebactrium parvum preparation is a preparation prepared by inactivating coryebactrium parvum through formaldehyde; and the noncellular coryebactrium parvum preparation is of a nanometer grade and has uniform grain size, enhanced absorbance and diffusance and low heat source without formaldehyde residuals. The CPP plays a certain role of resisting the novel A H1N1 influenza viruses, and especially, the effect of the NCP is more obvious.

The invention discloses a weeding composition containing glufosinate-ammonium and sulfonylurea herbicides. The weeding composition comprises glufosinate-ammonium an active ingredient A and an active ingredient B. A weight ratio of the ingredient A to the ingredient B is 200: 1 to 1: 1. The active ingredient B comprises a sulfonylurea compound with a structural formula (I). The weeding composition comprises 5-80wt% of the active ingredients and the balance auxiliary agents. The weeding composition can be processed to form wettable powder, water dispersible granules, a water suspending agent and an oil suspending agent, can be used for preventing and removing weeds, has effects better than that of single glufosinate-ammonium or active ingredient B, reduces a pesticide usage dosage, reduces pesticide-caused unfavorable influence on the ecological environment, has good preventing effects on cyperaceous weeds such as Cyperus rotundus difficultly removed by glufosinate-ammonium and can effectively treat weed resistance to herbicides.

The invention relates to a traditional Chinese medicine oral liquid used for curing hyperpyrexia of cattle, which comprises eight medicaments of honeysuckle, weeping forsythia, cortex moutan, dandelion, desmodium, bupleurum, prunella vulgaris and plaster. The invention has the function of heat-clearing and detoxifying, and purging intense heat and relaxing the bowels. Simultaneously, the dosage form of the medicaments are made into oral liquid which can be dispersed rapidly in drinking water, is taken by sick cattle through drinking water, thus being convenient for absorbing and achieving the purpose of taking effect rapidly.

The invention relates to an application of a Coryebacterium parvum preparation (CPP) or an non-cell Coryebacterium parvum preparation (NCPP) in the pharmaceutical field, and especially relates to the application in preparing medicaments for treating virus hepatitis B infection, and the application of the CPP/NCPP combined with a hepatitis B immunoglobulin (HBIG) or an anti-hepatitis B immunoglobulin (humanized/human anti-HBs) in preparing the medicaments for treating virus hepatitis B infection. The CPP is a preparation which is prepared through inactivating the CP with formaldehyde, and the CPP has the characteristics of nanometer level, uniform particle size, high absorption degree and diffusion degree, low heat source and no formaldehyde residual; and the CPP has a certain effect for resisting virus hepatitis B infection, and the NCPP has an obvious effect, and the CPP/NCPP combined with the HBIG/HBs has a more obvious effect.

The invention relates to a traditional Chinese medicine hemsleya root and also discloses an extraction method of hemsleyadin, the method is used for extracting the hemsleyadin, and the extraction method has simple method, low cost and high yield. The hemsleyadin can be made into various formulations according to the needs, such as oral liquid, tablets, injection, and the like, thereby being used for treating bacterial diseases of livestock and poultry, having good efficacy, overcoming the defects that the use of antibiotics for treating the bacterial diseases is easy to generate the drug resistance and easy to have residues in vivo as well as being widely applied in livestock breeding and production.

The invention relates to a traditional Chinese oral liquid for curing broiler ascites, which comprises nine medicaments of atractylodes, tuckahoe, umbellate pore furgus, areca peel, papaya, radix aucklandiae, amomum, semen pharbitidis and radix codonopsitis. The combination of the nine medicaments in the medicament prescription has the effects of replenishing qi to invigorate the spleen and inducing diuresis and excreting dampness, and quickening blood circulation, strengthening the oxygen carrying capacity of erythrocyte according to causes of the broiler ascites, and has the functions of reducing high pressure of lungs, increasing the oxygen supply and improving the organism immunity. Simultaneously, the formulation of the medicament combines the special physiological structure that genital tracts of poultry are short and can not digest wooden fibers to prepare the medicaments to be the oral liquid that can be dispersed quickly in the feeding water, and sick animals can take medicines by drinking water, of which is convenient and beneficial to absorb, thus achieving the purpose of quick effect.