34results about How to "Positive response" patented technology

A reduced pressure treatment appliance is provided for treating a wound on the body of a patient. In some embodiments, the appliance comprises a cover, which can have a top cup member and an interface member. The interface member can have flow control means, configured to permit exudate from the wound to flow through the flow control means into the volume under the cover, but not in the opposite direction. Also, in some embodiments, the top cup member can have a lid member, a cup body member, and lid attachment means to removably attach the lid member to the cup body member. In some embodiments, the cover can be configured to facilitate access to the wound for monitoring, treatment and other purposes without removing the cover from the body. The wound treatment appliance can have a vacuum system to supply reduced pressure to the site of the wound in the volume under the cover. A suction bulb can be used to provide a source of reduced pressure to the cover. Additionally, methods are provided for using various embodiments of the treatment appliance.

The present invention is directed to a sensor having continuous and discontinuous regions of conductive metallic nanoparticles capped with an organic coating which enables the detection of volatile organic compounds and/or water vapor.

Disclosed are the deactivation mechanism and chemistry platforms that make high-silicon hardmask films photo-imageable like positive-tone photoresist for microphotolithography. The deactivation mechanism requires a catalyst to promote crosslinking reactions, and a photoacid generator to deactivate the catalyst. The initial hardmask films are soluble in developers. If not radiated, films become insoluble in developers due to crosslinking reactions promoted by catalyst. If radiated, films remain soluble in developers due to deactivation of catalyst by photoacid generator. Compositions of positive-tone photo-imageable hardmask based on the chemistry of polysiloxane and polysilsesquioxanes are disclosed as well. Also disclosed is a method of modifying polysiloxane and polysilsesquioxane films for controlled diffusion of catalysts, photoacid generators, and quenchers. Further disclosed are processes of using photo-imageable hardmasks to create precursor structures on semiconductor substrates with or without an intermediate layer.

The present invention relates to methods of identifying a disease treatable with PARP modulators by identifying a level of PARP in a sample of a subject, making a decision regarding identifying the disease treatable by the PARP modulators wherein the decision is made based on the level of PARP. The method further comprises of treating the disease in the subject with the PARP modulators. The methods relate to identifying up-regulated PARP in a disease and making a decision regarding the treatment of the disease with PARP inhibitors. The extent of PARP up-regulation in a disease can also help in determining the efficacy of the treatment with PARP inhibitors. The present invention also relates to methods of identifying a disease treatable with PARP modulators by identifying a level of PARP in a plurality of samples from a population, making a decision regarding identifying the disease treatable by the PARP modulators wherein the decision is made based on the level of PARP. The method further comprises of treating the disease in a subject population with the PARP modulators. The methods relate to identifying up-regulated PARP in a disease and making a decision regarding the treatment of the disease with PARP inhibitors. The extent of PARP up-regulation in a disease can also help in determining the efficacy of the treatment with PARP inhibitors.

The present invention discloses various diseases that have up-regulated or down-regulated PARP and can be treated with PARP inhibitors or PARP activators, respectively. The examples of the diseases include cancer, inflammation, metabolic disease, CVS disease, CNS disease, disorder of hematolymphoid system, disorder of endocrine and neuroendocrine, disorder of urinary tract, disorder of respiratory system, disorder of female reproductive system, and disorder of male reproductive system.

A method and system for receiving, logging, answering, controlling, and forwarding calls from radio or other promoter call-in contestants, wherein said method provides an efficient means for controlling call-in contests. Radio call-in contests are the most typical, but the method applies to other types of promotions, such as direct mail, store banners and print ads. The system consists of a voice vendor, web server, database, telecommunications, and application software to control and count the calls and to provide administrative functions. Every caller receives a positive response, acknowledgement and notification of the caller number, and an opportunity to obtain other benefits, such as discounted items. Only the winning caller is forwarded to the radio station. The radio station only needs to answer to the winning caller. All other callers, including those callers after the winning caller is determined, receive a response on the first try, without needing to repeatedly redial to get through on the telephone line.

The invention discloses a single-system direct-cooling refrigerator and an auxiliary temperature control method for the single-system direct-cooling refrigerator. The single-system direct-cooling refrigerator comprises an indoor temperature sensor and a first heater, wherein the indoor temperature sensor is used for judging whether the refrigeration function needs to be started by acquiring the indoor temperature value in a refrigerating chamber, and the first heater is used for heating air at the position of the indoor temperature sensor. The auxiliary temperature control method for the single-system direct-cooling refrigerator comprises the steps that the environment temperature value is obtained, and whether the environment temperature value is lower than a preset low-temperature threshold value is judged; when the environment temperature value is lower than the preset low-temperature threshold value, the first heater is controlled to work. The single-system direct-cooling refrigerator and the auxiliary temperature control method for the single-system direct-cooling refrigerator have the advantages that the temperature of the refrigerating chamber is prevented from being too low, and the temperature of a variable-temperature chamber is prevented from being too high.

A fly reel spool rotatably coupled with a frame mounted on a fishing rod to wind a fish line includes a rotary frame rotatably coupled inside the frame; a winding drum having a ball-catching protrusion on an inner circumference coupling with the rotary frame, the winding drum configured such that the fish line is wound on or unwound from an outer circumference; a locking ball installed in an outer circumference of the rotary frame to protrude from and retract into the rotary frame; elastic means for elastically holding the locking ball so that it protrudes from the outer circumference of the rotary frame, whereby the locking ball is caught by one touch on the ball-catching protrusion on the inner circumference of the winding drum when the rotary frame is coupled with the winding drum, and stopping means for supporting the winding drum and the rotary frame to rotate together.

This invention relates to an information process device and a method for red alert system of image devices, in which, the device is composed of the following parts: an additional information test part testing EAS information from broadcast signals and a control part judging if it carries out the red alert operation based on the test EAS information, turning on the supply of the device if so to convert it to the channel appointed by the EAS information and increase volume, the process method includes: 1, searching for the EAS information from broadcast signals, 2, judging if it carries out red alert operation based on the EAS information, 3, turning on the device supply to convert it to the channel appointed by the EAS information if so.

Disclosed is a method for monitoring early treatment response of a cancer treatment comprising measuring by magnetic resonance spectroscopy (MRS), for example, proton MRS, the amount of Choline present in the endomembranes of the cancerous tissue before and after treatment; the treatment comprises administration of a cytotoxic therapy, whereby a decrease in the amount of Choline after treatment is indicative of a positive response. The decrease in the amount of Choline represents the decrease in the internal cell membrane as a result of down regulation of the organelles and their secretory granules and their transport vesicles. Disclosed also is a method for determining effectiveness of a cytotoxic treatment of cancer. In addition, a method for monitoring protein translation related to the cytotoxic treatment of cancer is disclosed.

A portable, easily body-mounted, light-weight hinged brace to build muscle groups by adding adjustable resistance at the joint

The present disclosure relates to the identification of genes and gene combinations that are correlated with patients having or being predisposed to developing pancreatic ductal adenocarcinoma (PDAC). In some instances, methods herein utilize panels of 5 or 10 genes to accurately diagnose PDAC, determine the likelihood of developing PDAC, or determine the severity/stages of PDAC. These panels may be used in a molecular diagnostic test.

The invention relates to an electrolyte additive, an electrolyte and a lithium battery, and belongs to the technical field of lithium batteries. The electrolyte additive comprises at least one of thecompounds shown in the structural formula I: a formula which is as shown in the specification, wherein R in the structural formula I is one of a fluorine group, a phenyl group, an alkyl group, and analkenyl group, wherein n is an integer of 1 to 5. According to the electrolyte additive, the electrolyte additive is subjected to a decomposition reaction in the electrolyte, and the obtained productgenerates a protective film on the surface of a positive electrode, so that a passivation effect is achieved, dissolution of a metal element in a positive electrode material and the collapse of the positive electrode material structure are inhibited, the electrochemical stability window of the electrolyte is improved, the working voltage range of the electrolyte is widened, and the cycling efficiency of the battery under a high voltage (for example 4.2-5.0V) can be effectively improved.

The invention discloses a GVU shielding box. The GVU shielding box comprises a shielding box body, shielding box end covers, a gas detecting sensor interface flange, a gas outlet flange, a gas inlet flange, a scavenging port flange and a pneumatic valve gas inlet and feedback interface, wherein openings are formed in the two ends of the shielding box body, the shielding box end covers cover the openings of the two ends of the shielding box body to form a containing space for containing a gas valve, the gas detecting sensor interface flange is used for installing a gas detecting sensor, the gas outlet flange and the gas inlet flange are used for connecting the GVU shielding box with an engine and a gas station, a valve in the GVU shielding box and gas in a pipeline can be connected with the outer side of a cabin through the scavenging port flange, and the pneumatic valve gas inlet and feedback interface conducts control and control feedback on the valve in the shielding box body. The GVU shielding box is high in integrity and compact and attractive in structure, makes the gas valve of the engine compactly and simply arranged, makes a gas supply system pipeline simply arranged, is attractive in overall appearance and reduces potential sealing leakage hazards.

The invention discloses a case of personal terminal device with an electric shocking function. The case comprises a case main body wrapping a personal terminal, a shocking part, an operation part, a multimedia part and a communication part. The shocking part is used for storing, allowing the case main body to be protruding, and receiving and amplifying electric power from a power supplying part of the case main body so as to allow the power supplying part to generate strong current. The operation part connects the power supplying part, the shocking part and a cell phone terminal and allows the shocking part to perform accelerated movement in a dangerous occasion. The multimedia part is arranged on one side of the case main body so as to collect sound or images of the scene according to the accelerated movement. The communication part connects the shocking part, the operation part, the power supplying part and the personal terminal with power and transmits the sound and the images collected by the multimedia part, and the current positions to a specific mechanism during the accelerated movement of the shocking part. The case has a function of protecting the personal terminal against external shocking. In addition, during the dangerous occasion, a terminal owner can protect and defend herself or himself with the case.

The invention relates to assembling equipment for a rotatable inductive probe. The assembling equipment comprises an assembling table body and a conveying slat mechanism arranged on the assembling table body, wherein a bottom cover input mechanism is arranged at the input port end of the conveying slat mechanism, a cross-under bearing input mechanism is arranged on one side of an input port of theconveying slat mechanism, an inductive probe delivery mechanism is arranged on one side of the rear portion of the cross-under bearing input mechanism, an inductive probe press fitting mechanism is arranged on the other side of the rear portion of the cross-under bearing input mechanism, the conveying slat mechanism is provided with an oil injection mechanism at one edge of the rear portion of the inductive probe press fitting mechanism, a cover cap input mechanism is arranged at one edge of the rear portion of the oil injection mechanism, and a cover cap press fitting mechanism is arranged at one edge of the rear portion of the cover cap input mechanism. The inductive probe assembled by the assembling equipment is not only added with a protective outer shell but also can be rotated and positioned, the assembled inductive probe is not only not easily affected by the external environment but also can make a positive respond to the external environment, the damage rate of the inductiveprobe is low, the service life is long, and the probe effect is good.

The invention provides a method for determining a prognosis of colorectal cancer in a colorectal cancer patient, comprising classifying said patient as having a good prognosis or a poor prognosis using measurements of a plurality of gene products in a cell sample taken from said patient, said gene products being respectively products of at least 1 of the genes listed in Table 1, or respective functional equivalents thereof, wherein said good prognosis predicts a positive response to standard chemotherapy regimens, and said poor prognosis predicts non-responsiveness. Provided herein, the invention includes a gene signature to predict which patients will to benefit from standard colon cancer therapy; alternatively, patients who are classified as non-responders may be more likely to benefit from a novel agent such as a Notch inhibitor.