An intelligent water affair data center station based on a distributed cloud architecture comprises a data collection layer, a data background layer, a service center station layer, a foreground application layer and an interaction layer, wherein the data collection layer has standardized access to data of an informatization system of each regional project in an API mode and collects data of external terminal equipment; wherein the data background layer comprises a basic database and a secondary processing database, the service center station layer processes basic data collected by a data background through a data processing tool, and the foreground application layer comprises a comprehensive display application, a project management service, a safe operation service, an evaluation serviceand a universal service. The interaction layer comprises a browser, a WeChat applet and a WeChat official account. Interaction tools comprise a large screen, a computer, a tablet personal computer and a mobile phone. According to the invention, standardized acquisition, storage, management, analysis, mining, sharing, exchange, display and application of water affair data of group-level-project-level multi-management-level projects can be realized.