The invention discloses an OUR-based sewage toxicity real-time early warning system. The OUR-based sewage toxicity real-time early warning system comprises a sewage filter, a sewage pump, an aerationpool, an aeration apparatus, two closed reaction pools, filamentous bacteria biological gel, zoogloea biological gel, two DO electrode probes, a PLC control early warning system and a water outlet, awater inlet of the sewage filter is connected with a water fetching opening on a pretreatment system and a biochemical pool connection pipeline, two ends of the sewage pump are respectively connectedwith water inlets of the sewage filter and the aeration pool, a water outlet of the aeration pool is connected with the closed reaction pool, the filamentous bacteria biological gel and the zoogloea biological gel are respectively arranged in different closed reaction pools, one DO electrode probe is arranged in each closed reaction pool, and both DO electrode probes are respectively connected with the PLC control early warning system. The OUR-based sewage toxicity real-time early warning system has the characteristics of real-time and multilevel early warning, intuitive effect, rapidness in early warning, stability and convenience in operation, and high efficiency and economy.