77results about How to "Sensitive and accurate" patented technology

The present invention provides novel compositions comprising Epstein-Barr virus-specific oligonucleotides that are useful as primers to amplify particular regions of the genome during enzymatic nucleic acid amplification. The invention also provides a rapid, sensitive and specific method for the detection and quantitation of the virus which may be present in a clinical specimen, using the virus-specific primers and enzymatic nucleic acid amplification; hybridization of amplified target sequences, if present, with one or more Epstein-Barr virus-specific oligonucleotide probes which are labeled with a detectable moiety; and detection of the detectable moiety of labeled oligonucleotide probe hybridized to amplified target sequences of Epstein-Barr virus DNA.

Provided are particle analyzers and related methods for verifying calibration status of the particle analyzer. The method includes the steps of providing an optical particle analyzer and modulating a power applied to a source of EMR. The method includes the steps of, in response to the modulating step, inducing a detector signal waveform and analyzing the detector signal waveform to determine a value of at least one diagnostic parameter associated with one or more of the source of EMR, an optical assembly, a chamber, a detector, and an optical collection system of the optical particle analyzer. The method includes the step of determining a calibration status of the optical particle analyzer based on the one or more determined values of the at least one diagnostic parameter.

Changes, increase or decrease, in the body fluid flow are passively detected by using a single pixel, non-linear blind de-mixing procedure, which can be extended to general biomedical measurement and diagnoses instruments. More specifically the single pixel, non-linear blind de-mixing procedure is applied on the hot spots of rheumatic arthritis or breast cancer detection problem using passive two-color infrared imaging as well as to passively detect blockages in the body fluid circulatory system that might be of importance for coronary artery bypass surgery, diabetes and deep vein thrombosis. Other applications of the mentioned algorithm include a pair of cameras for video, a pair of antennas for cell phones, and in situ data gathering or imaging using multiple mode fiberoptical sensing as well as selective amplification hearing aids through two-ear binaural processing for de-noise echo cancellation and signal classification.

The invention relates to a method for determining the sensitivity of each sensor in a mechanical equipment vibrating sensor network. A vibrating sensor network node sensitivity evaluation index is provided according to the actual conditions of the vibrating sensor network and by using common complex network importance evaluation indexes and methods as reference. The vibrating sensor network node sensitivity evaluation index is a sensor network sensitivity factor based on multi-feature fusion. The vibrating sensor network sensitivity factor must sensitively and accurately reflect system state change and measure the sensitivity of all sensors to the same state. The calculation thought of the vibrating sensor network sensitivity factor is characterized in that maximization of the distance between an abnormal fault state and a normal state can be achieved by using the normal state as reference; the factor is comparable, and the sensitivity of each sensor to the same fault or abnormal state can be measured. Compared with a single feature, the method has the advantages that the method considers more feature attributes, system state change can be comprehensively and accurately reflected, and the sensitivity of all the sensors to the same state can be well measured. In addition, by the method, the importance of the nodes of the sensor network can be evaluated and sorted, the key nodes can be found, and foundation is laid for sensor network consistency decision fusion.

The invention discloses a full-automatic bag making machine handle feeding and cutting device comprising a rack. The full-automatic bag making machine handle feeding and cutting device is characterized in that a handle feeding mechanism and a handle cutting mechanism are arranged on the rack. The handle cutting mechanism comprises a paper cutter. The handle feeding mechanism is connected with a material feeding power source in a transmission way. The paper cutter is connected with a material cutting power source in the transmission way. The handle feeding mechanism and the paper cutter are mutually cooperated to perform material cutting. The handle feeding mechanism stops material feeding in material cutting, and the handle feeding mechanism continues material feeding after completion of material cutting so that the degree of cooperation of the handle feeding mechanism and the handle cutting mechanism can be enhanced. The handle cutting mechanism is connected with the material cutting power source, the handle feeding mechanism is connected with the material feeding power source, and transmission of the handle cutting mechanism and the handle feeding mechanism is performed by the respective power sources so that the handle cutting mechanism and the handle feeding mechanism can be separately controlled, and machine debugging is more convenient.

An enhanced sensitivity laser vibrometer with increased output signal strength and more sensitive surface vibration detection, is provided by using a reflective mirror assembly to repeatedly bounce the sensing laser beam against the acoustic pressure-sensing diaphragm to magnify the acoustic incident pressure wave being detected. The enhancement in signal strength, in terms of power spectral density, is a function of the number of bounces squared and the detection of surface vibrations with a displacement of smaller than 4 picometers is demonstrated experimentally.

A process for assessing mitochondrial toxicity of a compound that includes contacting nucleic acids from a host with an amplification reaction mixture that contains at least two primers that provide detectable signals, wherein: a first primer provides a first detectable signal upon amplification of a host mitochondrial nucleic acid; a second primer provides a second detectable signal upon amplification of a host nuclear nucleic acid; and comparing the first and second detectable signals.

The invention provides a leaching device for processing heavy metal in house refuse and sludge by using citric acid, comprising a pedestal (4), a leacheate collecting tank (7), and a frame (8), wherein the periphery of the frame is provided with straight form support rotating rods (3), the axial two end portions of the straight form support rotating rods support a transmission chain, a crawler type filter screen conveyer belt (2) is fixed on the chain, a stainless steel sludge reserve tank (1) is fixed above the crawler type filter screen conveyer belt, an atomization spray system (6) is arranged above the stainless steel sludge reserve tank, and a set of filter screen cleaning devices (13) are arranged below the crawler type filter screen conveyer belt and above the leacheate collecting tank. The leaching device disclosed herein can continuously work, has large handling capacity, convenient maintenance, and low maintenance cost. The leaching device adopts bilayer rollers to drive and has no damage to the crawler type filter screen conveyer belt, thus multi-protection is realized, and the service life of the crawler type filter screen conveyer belt is prolonged.

The present invention relates to a method for the diagnosis of tumoural conditions and / or of the corresponding state of advance, wherein a sample from a patient comprising at least one tumour cell is obtained. According to the invention, a purified specimen of the at least one tumour cell is obtained by individually selecting and isolating single cells in a microfluidic device the purified specimen having a purity of at least 90%. On the purified specimen thus obtained there is subsequently performed a molecular analysis such as to highlight a characteristic thereof suited to enabling diagnosis.

The invention discloses a demonstrator key reaction sensitivity optimization method which includes the steps that an array type keyboard is adopted as a demonstrator keyboard in a demonstrator system, an independent keyboard scanning management chip is selected to reduce keyboard refresh frequency, an I2C bus mode is adopted in the keyboard scanning management chip, and meanwhile, in order to quickly respond to key pressing events in time and automatically eliminate jitters, an interrupt mode is selected to serve as a work mode of the keyboard; a central processor in the demonstrator system is responsible for coordination and management between modules of the system and detection of external interrupt and interrupt processing, and finishes communication tasks with a controller, a CAN bus structure with high anti-interference performance is adopted between the modules, multi-node efficient control is achieved by means of rich message structures, and multi-point real-time communication is achieved through programs in the system. The method is easy, convenient and quick to operate, movement of robots is flexible and accurate, and timeliness is high.

A mutation is introduced into the substrate-binding site of flap endonuclease to prepare a mutant with modified substrate specificity. Using the mutant as a reagent for the analysis of genetic polymorphism, the analysis of genetic polymorphism can be performed more accurately, easily and sensitively as compared with conventional methods.

The present invention relates generally to 3′-OH unblocked nucleotides and nucleosides labeled and unlabeled with 5-methoxy-substituted nitrobenzyl-based photocleavable terminating groups for use in methods and systems related to DNA and RNA sequencing and analysis. These compounds may be used as reversible terminators as they exhibit fast nucleotide incorporation kinetics, single-base termination, high nucleotide selectivity, and rapid terminating group cleavage that results in a naturally occurring nucleotide.

Methods, program product, and systems for single and multi-agent dosing are provided. An embodiment of a method for revising a cycle dose of at least one agent for a patient receiving a single or multi-agent therapy includes accepting as a first input the patient's cycle dose(s) of the at least one agent, accepting as a second input determination of the relevancy of at least one surrogate marker indicating a pharmacologic response of the patient and determining a revised dose of the at least one agent. Embodiments of systems and program products are also provided for use in calculating revised dose of at least one agent.

The invention provides a metal mesh touch display structure. The metal mesh touch display structure includes: a display device and a metal mesh structure; the metal mesh structure includes a bridge point, a first protective layer, first and second metal wires, and a second protection layer; the first and second metal wires are mutually insulated, the first metal wire forms a grid pattern corresponding to the shape of the first direction electrode of mutual capacitance, the second metal wire forms a grid pattern corresponding to the shape of the second direction electrode of mutual capacitance The first protective layer is provided with a via corresponding to the bridge point, and the second metal wire is connected to the bridge point through the via; the grid of the grid pattern is formed on light-shielding layer between the pixels of the display device. The invention also provides a corresponding manufacturing method.

The invention discloses a mobile robot. The mobile robot comprises a robot body and a collision sensing device, the robot body further comprises a control system, and the collision sensing device comprises a device shell and one or more inductive switches; the device shell at least surrounds the robot body for one circle, when the device shell is collided, one or more inductive switches are triggered and send signals, and the control system controls the mobile robot according to the signals; the inductive switches are arranged on the robot body and / or the device shell and used for sensing the collision condition of the collision sensing device. The mobile robot can sense the collision of the mobile robot in multiple directions.

The invention discloses a force application-adjustable manipulator and robot using the same. The manipulator comprises a mechanical arm and a mechanical wrist; the mechanical wrist comprises a wrist shaft and a gripper; the gripper is mounted at one end of the wrist shaft; the other end of the wrist shaft is movably connected with one end of the mechanical arm; the mechanical arm comprises a trigger baffle plate; one side of the trigger baffle plate is connected with one end of the mechanical arm; and the mechanical wrist comprises a trigger sensor, a sensor mounting base, a force application spring and a force application adjusting nut. The force application-adjustable manipulator and the robot using the same can adjust the pressure of the gripper to contacted objects through the force application spring and the force application adjusting nut, so that the force application allowing range of the mechanical wrist can be adjusted according to the pressure requirements of different contacted objects.

The invention relates to a protection device used for electric transmission line tower climbing operation, is particularly suitable for being used in overhead transmission line construction, interruption maintenance, operation with power uninterrupted and other tower climbing operation and belongs to the technical field of electric transmission line pole and tower field operation tools. The protection device comprises a safety rope with one end being hung on the human body, a plurality of short tying ropes which are arranged at intervals in the height direction of an electric transmission line pole and tower, and a differential speed blocking device which is used for clamping the safety rope which rapidly rotates anticlockwise. The differential speed blocking device is provided with a wire inlet which is used for penetrating the safety rope, a wire outlet and a clamping mechanism. The protection device is simple in structure, convenient to use, safe, reliable, wide in application range and high in operation efficiency.

The invention discloses an inductive sensor separated buoy applicable to viscous liquid level measurement. Through separated design of a sleeving ring and a floater, gaps between the buoy and a measurement rod are increased, a superposition area is reduced, when the buoy and the measurement rod carry out relative motion in viscous liquid, viscous force is reduced, and the motion is free and smooth.

A method for detecting lysosomal storage diseases including the steps of performing an assay for a single species of glycosaminoglycan contained in a specimen and correlating results of the assay with lysosomal storage diseases. A body fluid such as urine or blood can be employed as a specimen. The assay can be performed by use of a polypeptide that is capable of specifically binding to a glycosaminoglycan-containing molecule. The polypeptide may be an antibody, or a polypeptide having an antigen-binding site of an antibody.

A method is disclosed for analysing an image to assess a condition of an organ of a patient represented in the image. The method includes initially selecting a spatial resolution for an inspection matrix having a number of inspection regions each delimiting a part of the image. The inspection matrix is applied to the image and the part of the image within each of the inspection regions is analysed to determine a condition thereof. The condition is compared with a predetermined criterion and, if the condition is deemed to satisfy the criterion, the inspection region is identified, e.g. by annotating it with a colour. Finally a quantitative measure of an extent of the condition in the image is provided that is based on a number of the identified or annotated inspection regions.

CpG densities and sequence motifs that are characteristic of regions of DNA associated with epimutations and control of epimutations are provided. Such regions include, within approximately 400 (or fewer) base pairs, at least one, usually two, and preferably all three of the following features: i) a CpG density of 15% or less; ii) the presence of the sequence motif ATTTGTTTTTTCTTTTnT (SEQ ID NO: 1) where n is A, T, C or G, and statistically relevant variants thereof; and iii) the presence of the sequence motif GGGGGnGGGG (SEQ ID NO: 2), where n is A, T, C or G, and statistically relevant variants thereof.

Disclosed are antibodies and methods for detecting pregnancy in an animal. In certain aspects antibodies used binds immunologically to at least two PAGs selected from PAG4, PAG6, PAG9, PAG16, PAG17, PAG19, PAG20 and PAG21. Antibody encoding nucleic acids are also provided, as are kits, methods of use and additional antibody related compositions.

The invention provides a motor high temperature alarm and a method implementing high temperature alarm. The motor high temperature alarm includes a bridge circuit containing a platinum resistor and used for generating a corresponding first voltage by utilizing between-bridge-arm resistance unbalance caused by change of the resistance value of the platinum resistor; the platinum resistor embedded in a target position, used for monitoring the temperature of the target position and generating resistance change when the temperature of the target position changes; a voltage amplifier used for amplifying the first voltage output by the bridge circuit and outputting the amplified first voltage to a voltage comparator; the voltage comparator used for determining voltage threshold value, comparing the amplified first voltage with the voltage threshold value and triggering an alarm module for high temperature alarm when the amplified first voltage is greater than the voltage threshold value. The scheme provided by the invention can improve high temperature alarm accuracy effectively.