The invention relates to a synchronous zero-contact roll paper box for preventing cross-infection, which belongs to the technical field of daily necessities; Roll paper pushing device, shearing device, lower cutter, first driving wheel, second driving wheel, third driving wheel, transmission rod, connecting shaft, top-tightening roller support device, roll paper support rod, third driving wheel are installed in the shell. One driving roller bar, the second driving roller bar, the first tight roller bar, the third driving roller bar, and the second tight roller bar. Through the ingenious design of the structure, the present invention solves the problem of unhygienic and easy to cause cross-infection caused by tearing the roll paper with both hands, and also solves the problem of electric roll paper box and handle-driven roll paper box in the prior art. During the process of switching or turning the handle, bacteria and viruses on the user's hands will remain on the switch or the handle, which will also cause cross-infection problems.