51 results about "Beta-Hydroxy beta-methylbutyric acid" patented technology

A method of administering beta-hydroxy-beta-methylbutyric acid (HMB) is described, and specifically administering HMB-acid to a person such that the administration of free acid HMB results in an increase in effectiveness of HMB over administration of other forms of HMB, including a calcium salt HMB composition is described. Administration of HMB-acid results in an increase in the peak level of HMB in plasma compared with administration of a similar dose of a calcium salt HMB composition. Administration of HMB-acid results in a faster time to reach peak plasma levels of HMB relative to administration of a similar dosage of a calcium salt HMB composition.

The present invention relates to the compositions that enhance post-exercise recovery processes to increase both strength and muscle mass, replace glycogen stores, and prevent inflammation, resulting in the prevention and/or reduction of delayed onset muscle soreness. Additionally, it provides a feeling of muscle relaxation as well as a feeling of mental tranquility immediately following exercise. The composition consists of any or all high-glycemic sugars and/or polysaccharides (e.g., sucrose, glucose, maltodextrin), all essential amino acids and beta-hydroxy-beta-methylbutyrate and can include other amino acids sources (e.g. whey protein), performance enhancing agents (e.g., caffeine, L-glutamate), anti-inflammatory agents (e.g., ginger, boswellia, curcumen), antioxidants (vitamin C, vitamin E, selenium, polyphenols,), insulin-mimicking agents (cinnamon, Banaba), analgesics (e.g. aspirin, ibuprofen, naproxen, acetaminophen), and to methods of treating humans and animals by administration of these novel compositions to humans and animals in need thereof.

Disdosed are methods of treating an individual having a condition characterized by an imbalance in type 1 and type 2 cytokine production, wherein the method comprises administering to the individual an amount of β-hydroxy-β-methylbutyrate (HMB) effective to modulate or otherwise cause an increase in the ratio of type 1 to type 2 cytokines, induding an increase in the ratio of type 1 to type 2 cytokines without a corresponding increase in type 2 cytokine levels. Also disdosed are methods of using HMB to treat asthma and allergies. The methods of the present invention are based upon the discovery that HMB modulates cytokine production, most typically by increasing type 1 cytokines without a corresponding increase in type 2 cytokines.

The invention provides a preparation method of a feed additive calcium beta-hydroxy-beta-methylbutyrate. The preparation method comprises the following steps: 1) performing reaction on glacial acetic acid, sulfuric acid and H2O2 and performing reduced-pressure distillation after the reaction to obtain a peracetic acid solution; 2) mixing the product obtained in the step 1) and diacetone alcohol, adding methyl acetate serving as a solvent, reacting, and distilling and collecting 70-DEG C fraction after the reaction, wherein the residuum after distillation is a beta-hydroxy-beta methylbutyric acid solution; 3) adding water into the distillation residuum obtained in the step 2), adding a sodium hydroxide solution, adjusting the pH value to be 6.0 to 7.0, separating out calcium beta-hydroxy-beta-methylbutyrate, filtering and drying to obtain the product. The preparation process of the calcium beta-hydroxy-beta-methylbutyrate is simple and avoids environmental pollution. The prepared product has high quality, is stable and reliable, and is convenient to popularize.

The invention relates to a composition with a muscle gain function, which comprises the following active ingredients of creatine, taurine, beetroot extract and beta-hydroxyl-beta-methyl butyrate. The invention further provides a sports drink comprising the composition, and the sports drink comprises the composition and a food additive. The sports drink has the functions that the muscle blood stream can be increased, the oxygen utilization rate can be enhanced, the sports energy consumption can be reduced, so that the motion function can be improved.

Disclosed are nutritional compositions comprising a peroxide-treated aseptic package and a nutritional liquid contained therein, wherein the nutritional liquid comprises beta-hydroxy-beta-methylbutyrate (HMB) and at least one of fat, carbohydrate, and protein. The HMB provides a buffering effect in the nutritional liquid to thus minimize an acidic pH shift that is prevalent in aseptically sterilized packages, and thus helps maintain product stability over time.

Disclosed are methods for enhancing neural function in an individual, such as an older adult. The methods include administering nutritional compositions comprising HMB to the individual. The nutritional compositions provide benefits for individuals that have or may be at risk of having cognitive decline, cognitive impairment, and neural dysfunction, typically resulting from cognitive diseases associated with neurodegenerative diseases.

The invention discloses granules with an anti-fatigue and health-care function. The granules are prepared from following main components: 0.1g-5g of creatine, 1g-3g of calcium beta-hydroxy-beta-methyl butyrate, 1g-10g of fructose, 1g-500g of protein powder, 3g-9g of pseudo-ginsengs, 9g-30g of codonopsis pilosula, 10g-15g of radix puerariae, 9g-27g of acanthopanax senticosus, 6g-12g of American ginsengs and 0.1g-1.4g of taurine. The granules with the anti-fatigue and health-care function have the anti-fatigue and health-care function; the malnutrition is improved; the granules have an obvious effect to promote the recovery after exercises.

The invention aims to provide an artificial compound feed for improving the meat quality of turbots. The artificial compound feed provided by the invention respectively comprises the following components in percentage by weight: 35-60% of brown fishmeal, 15-30% of wheat meal, 1-5% of beer yeast, 0.5-3% of compound vitamins, 0.5-3% of compound mineral elements, 0.05-3% of beta-hydroxyl-beta-methyl calcium butyrate, 2-6% of fish oil, 1-5% of soya bean lecithin, and 0.05-1% of choline chloride. The artificial compound feed provided by the invention is capable of increasing the growth speed of turbots, reducing the body fat level, increasing the hardness, the chewiness and the elasticity of turbots, improving the mouth feel of turbots, increasing the number of unit area turbot muscle fibres and reducing the cross section area of the muscle fibres; therefore, the meat quality is more delicate and the elasticity is achieved; furthermore, the survival rate, the feeding rate, the feed efficiency, the hepatosmatic index, the organ-body ratio and the fatness of turbots are not influenced; and the ash content, the water content and the protein components of turbot bodies are not influenced.

The invention discloses a special milk tea powder for fitness and body-building and a preparation method of the special milk tea powder, and belongs to the technical field of formula milk powder and nutritional food. The special milk tea powder is characterized by being prepared from 76-90 percent of skim milk powder, 5-20 percent of maltodextrin, 2-5 percent of instant tea powder and 0.5-3 percent of calcium beta-hydroxy-beta-methyl butyrate. The special milk tea powder has the advantages that the problems of bad taste of the calcium beta-hydroxy-beta-methyl butyrate and the like are solved; the effects of nutrition complementation and collaborative gain are achieved; the market vacancy is filled; the milk tea powder tastes good, is convenient to eat, high in safety and high in acceptability, and does not have toxic and side effects; the damage degree of muscular tissues during exercise is obviously reduced; the decomposition of muscle proteins after strenuous exercise is reduced, and the lean body mass is increased; fat can be combusted, and endurance is improved; exercise induced fatigue is resisted, and the exercise capacity of an organism is improved; the milk tea powder is simple in production process and easy to produce, and has an extremely large market developing potential.

The present invention relates to a method for purifying β-hydroxyl-β-methyl butyrate, comprising neutralizing a crude β-hydroxyl-β-methyl butyrate with a base to produce a salt of β-hydroxyl-β-methyl butyrate, cooling and crystallizing, dissolving and acidifying, and extracting to obtain β-hydroxyl-β-methyl butyrate of high purity. No strict conditions, such as high temperature and high vacuum, are required in this method. On the contrary, it has low requirement on the apparatus, the process can readily be controlled and a product with high purity can be produced.

Disclosed are shelf stable nutritional products including beta-hydroxy-beta-methylbutyrate (HMB) and an oxidatively active species such as iron or copper. The HMB restricts the capacity of the oxidative species to catalyze the oxidation of nutrients such as fatty acids and vitamins thereby imparting both nutritional benefits and sensory benefits to the nutritional products.

The present invention provides a composition comprising HMB and methods of using HMB to mitigate loss of lean body mass, increase fat free mass, improve muscular performance, increase body fat loss and decrease body fat percentage in individuals undergoing intermittent fasting.

The use beta-hydroxy-beta-methylbutyric acid for improving glucose tolerance in a pediatric individual or in an adult individual is disclosed. In certain embodiments, the beta-hydroxy-beta-methylbutyric acid is administered via a nutritional composition.

The invention discloses a method for preparing and purifying calcium beta-hydroxy-beta-methylbutyrate. The method comprises the following steps: performing haloform reaction by taking sodium hypochlorite as a reaction raw material and diacetone alcohol as a solvent, then performing acidification and ethyl acetate extraction, salifying beta-hydroxy-beta-methyl butyric acid in an ethyl acetate extract and calcium hydroxide and purifying through a cryogenic kettle and a plate and frame filter press to prepare the calcium beta-hydroxy-beta-methylbutyrate. The method disclosed by the invention hasthe advantages of being simple in production process, safe, non-toxic, cheap, convenient to recover and high in crystal purity and yield; meanwhile, a large number of impurities are removed through plate and frame separation, so that the product content is improved, the efficacy is improved, and the labor cost is reduced.

The invention discloses a milk tablet for improving endurance and a preparation method of the milk tablet, and belongs to the technical field of processing of dairy products. The milk tablet is characterized by comprising the following raw materials by weight percent: 70-87% of whole sugar powder, 5-25% of maca powder and 5-8% of beta-hydroxy-beta-methylbutyric acid calcium. The milk tablet has the advantages that the defects of poor taste and the like of the beta-hydroxy-beta-methylbutyric acid calcium and the maca powder are fully overcome, the beta-hydroxy-beta-methylbutyric acid calcium and the maca powder have synergic effects, the problems of muscle injury, fatigue and the like when people exercise are solved, and the milk tablet is simple in production technology, and easy to produce, and has market development potential.

The invention discloses a beta-hydroxyl-beta methyl calcium butyrate preparation method which comprises the steps: mixing sulfuric acid, glacial acetic acid and hydrogen peroxide, performing primary constant-temperature reaction and distilling and collecting peracetic acid; mixing peracetic acid and diacetone alcohol, adding methyl acetate, performing secondary constant-temperature reaction and distilling and collecting beta-hydroxyl-beta methylbutyric acid; adding water into the beta-hydroxyl-beta methylbutyric acid, adjusting a solution pH, heating, dissolving and filtering, taking filtrateand adding calcium chloride, stirring and reacting, adjusting a pH, separating out beta-hydroxyl-beta-methyl calcium butyrate, filtering and drying to obtain the beta-hydroxyl-beta methyl calcium butyrate and superfinely grinding to obtain a product. The beta-hydroxyl-beta methyl calcium butyrate prepared by the preparation method disclosed by the invention has the advantages of high yield, high-efficiency and environment-friendly in synthesizing method, ability in meeting a green chemical synthesizing idea and a wide market prospect.

According to one embodiment, a nutritional supplement for suppressing an appetite while maintaining muscle mass of a subject during weight loss is provided. The nutritional supplement includes beta-hydroxy beta-methylbutyric acid (HMB), chromium, and Caralluma fimbriata.