107 results about "Bone reconstructions" patented technology

A system and method are provided that use a formable bone plate and a clamping apparatus for small bone reconstruction. The formable bone plate includes a plate body having a plurality of nodes separated by internodes. Each node includes a hole formed therein for receiving a screw, wire, tack, or other fixation device screwed or placed into a bone. A clamp engages an engagement section of the node to facilitate bending of at least one of the internodes to contour the plate to the bone in-situ or ex-situ and when at least partly screwed to or not screwed to the bone.

Systems and methods are provided for designing and producing custom-made templates for implantation or for pre-contouring metallic or polymer implantable plates prior to surgery. According to one embodiment, medical image data representing surrounding portions of a patient's anatomy to be repaired by surgical implantation of a bone reconstruction plate is received. Next, three-dimensional surface reconstruction is preformed based on the medical image data. Virtual removal of a bone or portion thereof to be reconstructed is performed with reference to the medical image data by simulating the contemplated surgical implantation procedure. Then, a representation of a template is created that is countered to fit the patient's anatomy to be repaired. Finally, a replica of the template is produced by using Solid Freeform Fabrication manufacturing techniques.

Disclosed are porous ceramic balls with a hierarchical porous structure ranging in size from nanometers to micrometers, and preparation methods thereof. Self-assembly polymers and sol-gel reactions are used to prepare porous ceramic balls in which pores ranging in size from ones of nanometers to tens of micrometers are hierarchically interconnected to one another. This hierarchical porous structure ensures high specific surface areas and porosities for the porous ceramic balls. Further, the size and distribution of the pores can be simply controlled with hydrophobic solvent and reaction time. The pore formation through polymer self-assembly and sol-gel reactions can be applied to ceramic and transition metals. Porous structures based on bioceramic materials, such as bioactive glass, allow the formation of apatite therein and thus can be used as biomaterials of bioengineering, including bone fillers, bone reconstruction materials, bone scaffolds, etc.

The present invention provides an improved contourable surgical fixation device that is made from a resorbable material and useful in bone reconstruction. In one embodiment, the fixation device may be made of a polymeric material. The fixation device comprises a plurality of spaced-apart fastening plates, links interconnecting the plates, and openings defined between the fastening plates by the links and fastening plates. In one embodiment, at least some of the fastening plates have fastener holes therethrough for receiving a fastener, such as a screw or tack, to secure the fixation device to the bone. The present invention provides an open-structured fixation device that is capable of being contoured in three dimensions to approximate the anatomical shape of a bone to which the fixation device may be attached.

Disclosed is a guided bone regeneration membrane including a novel mechanism that effectively induces a bone reconstruction ability. The mechanism is provided by forming a bi-layered structure of a first nonwoven fabric layer containing a silicon-releasable calcium carbonate and a poly(lactic acid) as principal components and a second nonwoven fabric layer containing a poly(lactic acid) as a principal component; and coating the first nonwoven fabric layer with an apatite. The guided bone regeneration membrane is available by using a nonwoven fabric manufacturing technique through electrospinning and a simulated body fluid soaking technique.

The invention provides a fluid cement for medical use for bone reconstruction, in particular for filling the vertebral body, and a binary composition which is intended for the preparation of such a cement. The invention also provides a device for conditioning the binary composition, and a method of preparing a bone cement from a binary composition. The fluid cement according to the invention comprises: a) approximately 60% to 85% by weight of a polymer comprising a polymethylmethacrylate and a methylmethacrylate monomer and b) approximately from 15 to 40% by weight of a radio-opaque composition. Preferably, the radio-opaque composition comprises a radio-opacifier, such as barium sulfate and zirconium dioxide, in a mixture with a calcium phosphate, for example apatite hydroxide.

The invention relates to a biologically degradable composite material and to a process for the preparation thereof. The biologically degradable composite material according to the invention is preferably a bone reconstruction material which can be used in the field of regenerative medicine, especially as a temporary bone defect filler for bone regeneration.

The invention relates to a novel calcium supplementing preparation with functions of improving bones and joints, which is prepared from the following raw materials in parts by weight: 10-42 parts of calcium source components, 5-25 parts of amino sugar components, 0.1-5 parts of casein phosphopeptide, 0.5-5 parts of bone collagen protein, 0-8 parts of oxidation resistant components for human bodies and 0-3 parts of filling agents. The novel calcium supplementing preparation not only can supplement a calcium source to increase the bone hardness, but also can supplement bone collagen protein to increase the bone toughness for preventing calcium loss; the casein phosphopeptide is added to promote the calcium absorption, thereby solving the problem of the calcium absorption in the calcium supplementing process; and simultaneously, the oxidation resistant components and the components for promoting osteoblast proliferation are added to enable the bone reconstruction process formed by bone formation and bone absorption to balance again, thus the supplemented calcium can be reserved and firmly deposited on the bones. The related components in the novel calcium supplementing preparation can restore cartilages, improve the joint structure and interdict the deterioration of osteoarthritis.

This device can be used to create new bone to fill a gap in the mandible after surgical excision. It uses a bone reconstruction plate as a distraction device. The reconstruction plate fixes the bone stumps on both sides of the bone gap. In the middle segment of the plate overlying the bone gap, the transport bone disc is carried on a transport unit that moves along a rail on the outer surface of the reconstruction plate.

The invention relates to surgical guides which are of use during reconstructive bone surgery for guiding a surgical instrument or tool. More particularly, the guides are characterized in that they are fitted to the implant rather than to the bone.

An implant (5) for ligament and/or bone reconstruction is composed of biodegradable material suitable to be remodeled into vital bone and having mechanical strength for securely fixing a ligament in a bore or hole in bone with a press or form fit and/or reshaping a collapsed surface of bone into original shape. A surgical instrument (9) for ligament and/or bone reconstruction can be used to insert the implant (5) into bone and has a shaft member (3) having a first end (11), a second end and a longitudinal bore (15) having an inner diameter and pushing member (4) having a first end, second end and piston (16) in turn having an outer diameter smaller than or equal to inner diameter of the bore (10) so that the piston (16) of the pushing member (4) can be slidably arranged within the longitudinal bore (10).

The invention relates to a fibula near-end bone tumor focus removing guider and a preparation method thereof. The fibula near-end bone tumor focus removing guider comprises a patient CT (Computed Tomography) scanning film, a bone reconstruction device, a guider construction device and a 3D (Three-dimensional) printer, wherein a CT scanning film reading port is formed in the input end of the bone reconstruction device; the patient CT scanning film is arranged in the CT scanning film reading port; a CT scanning film data analysis module is arranged in the bone reconstruction device; the output end of the CT scanning film data analysis module is connected with the input end of the guider construction device; the output end of the guider construction device is connected with the input end of the 3D printer. By directly utilizing a digital visualization bone tumor focus guider 3D printing working platform designed in the invention, a clinician inputs the CT data information of a surgical patient, a guider can be designed and prepared, the surgical accuracy is greatly improved, and the surgical risk is reduced.

The invention discloses a bone reconstruction principle-based personalized anterior interbody fusion cage design method, which comprises the following steps of A, acquiring a vertebral body image andperforming three-dimensional reconstruction to obtain a three-dimensional vertebral body model; B, establishing an initial model of the anterior interbody fusion cage; C, establishing a vertebral body-initial fusion cage model; D, establishing a cone-initial fusion cage finite element model; E, optimizing density distribution of an initial fusion cage finite element model in the cone-initial fusion cage finite element model; updating the material attribute of the anterior interbody fusion cage initial model by adopting a bone reconstruction method to obtain an optimized density distribution cloud picture of the initial fusion cage finite element model; F, shaping to obtain an anterior interbody fusion cage model; and G, estimating the effect of the anterior interbody fusion cage model after the anterior interbody fusion cage model is implanted into the vertebral body. The method not only has the characteristic of improving the strength of the fusion cage, but also has the characteristic of being conveniently fused with a vertebral body.

The invention belongs to the field of tissue-engineered bones, and in particular relates to a method for preparing an electrospinning bionic periosteum. The method specifically comprises the steps that polysaccharide matrix solution and macromolecule protein are mixed and fully stirred, so that endosteum electrospinning liquid is obtained; the polysaccharide matrix solution is used as periosteum electrospinning liquid; an electrospinning device is applied to prepare periosteum electrospinning from the periosteum electrospinning liquid; and the bionic periosteum at least contains two layers, one layer is a bionic endosteum, and the other layer is a polysaccharide matrix periosteum which is prepared on the basis of electrospinning. According to the method, polysaccharide matrix is used as a carrier, can protect the endosteum and can prevent the interference factors of the peripheral environments, which are not beneficial to bone reconstruction; and according to the endosteum, recombinant fibronectin/cadherin chimera (rFN/CDH) fusion protein which can effectively enhance mesenchyal stem cells (MSCs) adhesion, multiplication efficiency and viability and is obtained after long-term work is buried in low molecular weight chitosan nanofibers through a blending mothod, and along with the degrading and absorbing of the chitosan fibers, the fusion protein rFN/CDH is exposed out of the surfaces of membrane materials.

The invention discloses a drug release-controlled calcium phosphate bone cement composite microsphere and a preparation method and application thereof. The preparation method comprises the following steps of compounding silk fibroin and carboxymethyl chitosan; using a calcium phosphate bone cement solid-phase powder as the raw material, and combining with a liquid droplet condensing method, so asto obtain the calcium phosphate bone cement composite microsphere. The preparation method has the advantages that the preparation method is simple, and the high-temperature sintering is not required;the calcium phosphate bone cement composite microsphere has higher mechanical strength, and good anti-collapsing property, degradability and cell compatibility; the mesoporous calcium silicate contains a large amount of mesopores and can adsorb the drug, and the medicine release-controlled effect is realized after the mesoporous calcium silicate as a drug carrier is added into the calcium phosphate bone cement microsphere, so that the calcium phosphate bone cement microsphere has the effects of bone reconstruction and drug treatment.

The invention discloses a PEKK individualized implant design and manufacture method for reconstruction of a mandible box defect. The PEKK individualized implant design and manufacture method includesthe following steps that (1) establishment of image acquisition and a three-dimensional model is conducted; (2) determination and design of abutment position are conducted; (3) design of a fixed unitis conducted; (4) design of a support unit is conducted; (5) design of a boundary grid surface is conducted; (6) the support unit, a fixed unit, the boundary grid surface and a base are combined through boolean operation, and the three-dimensional model of the PEKK implant is obtained; (7) the implant is integrally printed to be shaped and a guide plate of a resection operation in an inpatient ward are printed out at the same time by a 3D printing technology; and 8) the post-processing is conducted, and a PEKK individualized implant with functions of bone reconstruction and dental implant repair can be used clinically and used for the reconstruction of the mandible box defect is obtained. The invention further provides the PEKK individualized implant for the reconstruction of the mandiblebox defect. According to the PEKK individualized implant design and manufacture method and the PEKK individualized implant, the mechanical strength is enough to support the load, enough pore space isprovided used for transmitting a biological agent, and inward growth of bones can be stimulated.

The invention relates to an orbital margin tissue engineering bone and application thereof. The orbital margin tissue engineering bone is prepared by the following steps: 1, culturing and inducing bone seed cells; 2, preparing an individual bone repair scaffold; and 3, combining the bone seed cells and the bone repair scaffold in vitro and culturing, wherein the bone seed cells cultured to a second generation are combined with the bone repair scaffold in the step 3 to form a compound of the bone seed cells and the bone repair scaffold. Similar to the tissue structures and characteristics of normal orbital margins, the orbital margin tissue engineering bone constructed and cultured in vitro can facilitate autogenous bone regeneration while a bracket material is degraded, generate rational bone reconstruction and finally be replaced by autogenous bone tissues in vivo so as to realize dual-repair of the shape and the function.

A system is disclosed for repairing and reconstructing an injured intra-articular, extra-articular ligament or tendon to a bone. The system includes realigning the axis of a bone, and further includes fixing fragments of a bone together. Novel devices, instruments and methods are disclosed, including a cortical loop for engaging a bundle of soft-tissue and capturing the bundle against a bone surface, an anchor for stabilizing a fractured bone, a guide for directing an orthopedic blade, and a hinged external jig arranged to position and guide the blade. Methods are disclosed for connecting soft-tissue to a bone and for bone alignment.