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41 results about "Cleft palates" patented technology
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A cleft palate is an opening or split in the roof of the mouth that occurs when the tissue doesn't fuse together during development in the womb.
Process for producing a pharmaceutical preparation for therapeutic treatment of endometriosis containing a combination of a gestagen and (6S)-5-methyltetrahydrofolate
InactiveUS20090060997A1Reduce endometriosisEffective therapeutic treatmentBiocidePill deliveryBone densityObstetrics
A combination of an anti-androgenic gestagen at a daily dose of from an ovulation-inhibiting dose up to at most twice the ovulation-inhibiting dose and from 0.1 to 10 mg of (6S)-5-methyltetrahydrofolate are used to produce a pharmaceutical preparation for therapeutically treating endometriosis while simultaneously reducing therapy side effects including the negative effect on bone density and / or bone metabolism, reducing the risk of osteoporosis and, in the event of pregnancy, reducing the risk of congenital malformations, such as medullary tube defects, cleft lip, cleft jaw, or cleft palate, and the risk of pregnancy complications, such as detachment of the placenta and premature birth. The preparation is suitable for long-term administration, which continues daily for at least 169 days to at least two years.
Owner:BAYER SCHERING PHARMA AG
Hydrogel membrane composition and use thereof
InactiveUS20040096505A1Change propertiesChange structureBiocidePowder deliveryMeth-Organic chemistry
The invention disclosed is a hydrogel composition for use as dural substitute, for wound closure of cleft palate and regeneration, and as substrate for cell delivery to the eye. The hydrogel is made of a copolymer of (a) an N-substituted (meth)acrylamide, and (b) a hydroxyalkyl (meth)acrylate, which is covalently crosslinked with dimethacrylate monomers. The swollen, gel is in the form of a sheet or membrane that is readily sterilisable, being homogeneous or heterogeneous, non-degradable, non resorbable, elastically deformable, and has an equilibrium water content of at least 50%.
Owner:WOERLY STEPHANE
Cleft palate voice glottal stop automatic identification algorithm and device
InactiveCN104992707ARealize automatic identificationImprove recognition accuracySpeech recognitionSyllableGlottal stop
The invention discloses a cleft palate voice glottal stop automatic identification algorithm and device, relates to the technical field of voice analysis and identification, and aims to provide a glottal stop automatic identification method and device. A computer is adopted for automatically identifying cleft palate voice glottal stops, effective and objective auxiliary diagnosis is provided to patients and voice teachers, and wide popularization of cleft palate voice assessment and voice treatment is facilitated. According to the technical key points of the invention, the method comprises the steps of: 1, collecting voice signals of syllables to be tested; 2, carrying out initial and final division on the voice signals of syllables, and retaining initial voice signals; 3, extracting characteristic values of the initial voice signals; and 4, sending the characteristic values into trained identification models, wherein the identification models judge whether glottal stops exist in the voice signals of syllables according to the characteristic values.
Owner:SICHUAN UNIV
Shape appliance digitalizing method of cleft palate alveolar bone
InactiveCN102169519AHigh precisionRealize individual precise designSpecial data processing applicationsShape changeNon invasive
The invention belongs to a non-invasive treating method of congenital cleft palate in the medical field, especially relating to a shape appliance digitalizing method of a cleft palate alveolar bone, which comprises the following steps of: 1) obtaining the jaw arch fault information of a cleft palate alveolar bone by using the microscopic CT (computed tomography) technology, wherein the thickness of a scanning layer is 50 mu m; 2) moving the cleft palate alveolar bone segment of a maxillary arch solid model to approach to a normal maxillary arch form from an abnormal form in a simulation manner in reverse engineering software, and simulating and demonstrating the shape change process step by step; 3) obtaining a digitalized model of the cleft palate alveolar bone jaw arch in each stage in the process of remedying according to the simulation and demonstration; 4) manufacturing an appliance retention column digitalized model used in each stage of shaping the alveolar bone according to the digitalized model of the cleft palate alveolar bone jaw arch; and 5) automatically processing a prototype of an alveolar bone shape appliance by using the rapid forming technology. A digitalized designing and manufacturing method of the shape appliance of a cleft palate alveolar bone independent of the experience and handwork of a doctor is provided.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY
Periodontal Subperiosteal Tunnel Bone Graft Technique
Tunnel bone grafting according to the proposed method can be used when an individual has a facial bone defect due to periodontal disease, cleft palate or trauma. The proposed method can be utilized for implant placement, it reduces wrinkles and supports facial muscle in order to make the individual look younger. The method can also be used to create a thicker alveolar ridge in order to stabilize full dentures or partial dentures. Its advantages over conventional guided bone regeneration techniques is that the proposed method is minimally invasive and lessens trauma to patients, prevents soft tissue opening, and reduces surgery time. Specifically, it minimizes the incision size and thus reduces trauma to the patient. Further, this reduces the risk of complications, including excessive bleeding, due to the minimization of the incision size. There is also considerable reduction in post surgery swelling using the proposed method as opposed to conventional techniques.
Owner:JEONG SUNG JOO
Nursing device
InactiveUS20130186915A1Minimize the possibilityLarge containersOral administration deviceCouplingDisplay device
A nursing device for feeding infants with a cleft lip and / or cleft palate includes upper and lower portions. The upper portion includes a bottle with an opening in its top for containing a liquid, a nipple and a screw cap for maintaining the nipple in sealing engagement with the opening. A submersible pump is disposed in the bottom of the bottle and connected to an opening in the nipple by a tube. A lower portion of the device includes a motor and a magnetic coupling for activating the pump. A microprocessor control timer includes means for regulating the timing and flow of a feeding cycle with a display for help in regulating the feeding cycle. Alternatively, the motor, pump, controls, and power supply may be disposed at the top of the bottle as a removable unit.
Owner:AL THALAB FATEMAH S
Application of allograft acellular dermal matrix in oral diseases
The invention relates to application of an allograft acellular dermal matrix in oral diseases, in particular to application of the allograft acellular dermal matrix in the repairing of cleft lip and / or alveolar cleft, cleft palate and oral mucous membrane defect, the repairing of periodontal defect and gingival recession, the repairing of nasal mucosa, tooth implantation, the repairing of furcation involvement and the prevention of complications such as dry socket after impacted tooth extraction, and belongs to the technical field of biological medical material tissue engineering. The allograft acellular dermal matrix is a product improved by a process, the mechanical performance of the product is suitable for surgery, and the sewing strength of the product is 16-18N; the allograft acellular dermal matrix is free of immunological rejection, capable of fast inducing tissue regeneration, soft in texture after implantation, free of contour feeling and good in in-vivo compatibility and hasa stable stent and template effect.
Owner:BEIJING JAYYALIFE BIOTECH CO LTD
Nursing device
A nursing device for feeding infants with a cleft lip and / or cleft palate includes upper and lower portions. The upper portion includes a bottle with an opening in its top for containing a liquid, a nipple and a screw cap for maintaining the nipple in sealing engagement with the opening. A submersible pump is disposed in the bottom of the bottle and connected to an opening in the nipple by a tube. A lower portion of the device includes a motor and a magnetic coupling for activating the pump. A microprocessor control timer regulates the timing and flow of a feeding cycle with a display for help in regulating the feeding cycle.
Owner:AL THALLAB FATEMA S
Nursing device
InactiveUS20130161280A1Minimize the possibilityOral administration deviceFeeding-bottlesEngineeringBottle
A nursing device for feeding infants with a cleft lip and / or cleft palate includes a nipple body and a tube operatively attached at one end to a pump for pumping liquid and operatively attached at the other end to the nipple body. The tube passively regulates the amount of liquid being pumped, ensuring that the infant can feed with minimal mess from the infirmities of cleft lip and / or cleft palate. The nipple body includes an outer flange and a cap for sealing engagement with the top of a nursing bottle. A shield can be used to cover the nipple body, which serves to protect and form a temporary reservoir for the liquid dispensed through the nipple body.
Owner:THALAB FATEMAH S AL
Cleft palate speech initial and final automatic segmentation method and system
The invention discloses a cleft palate speech initial and final automatic segmentation method and a cleft palate speech initial and final automatic segmentation system, which relate to the field of speech signal processing technologies, especially a cleft palate speech initial and final automatic segmentation technology. The invention aims to provide an initial and final automatic segmentation algorithm for cleft palate speech to solve the technical problem that an initial and final automatic segmentation algorithm for the cleft palate speech does not exist in the prior art. The cleft palate speech initial and final automatic segmentation method is characterized by carrying out the processing steps on a syllable including an initial: a quasi voiced initial and a quasi voiceless initial distinguish step, which is used for distinguishing whether the syllable is a syllable comprising a quasi voiced initial or one comprising a quasi voiceless initial; an initial and final segmentation step for the syllable comprising the quasi voiced initial; and an initial and final segmentation step for the syllable comprising the quasi voiceless initial.
Owner:SICHUAN UNIV
Nursing device
InactiveUS8568351B2Minimize the possibilityOral administration deviceFeeding-bottlesEngineeringBottle
A nursing device for feeding infants with a cleft lip and / or cleft palate includes a nipple body and a tube operatively attached at one end to a pump for pumping liquid and operatively attached at the other end to the nipple body. The tube passively regulates the amount of liquid being pumped, ensuring that the infant can feed with minimal mess from the infirmities of cleft lip and / or cleft palate. The nipple body includes an outer flange and a cap for sealing engagement with the top of a nursing bottle. A shield can be used to cover the nipple body, which serves to protect and form a temporary reservoir for the liquid dispensed through the nipple body.
Owner:THALAB FATEMAH S AL
Method of treatment and compositions of D-chiro inositol and phosphates thereof
InactiveUS20080103116A1Prevent and reduce chanceReduce or prevent fetal malformation occurrenceBiocideHydroxy compound active ingredientsD-chiro-InositolPhosphate
The present invention relates to the use of D-chiroinositol or a phosphate thereof in combination with folate for the reduction or prevention of congenital deformations such as anorectal malformations, neural tube defects, cleft-lip, cleft palate, and other birth defects. The invention further relates to the use of D-chiroinositol or a phosphate thereof in quieting or preventing the sensitivity of breast tissue to estrogenic, progestogenic, and or anti-androgenic insult, whether from environmental, dietary, or medicinal sources. Co-therapies as well as combination products of D-chiro-inositol (or a phosphate thereof) with at least one of (a) a folate source and (b) one or more of an estrogenic substance, a progestogenic substance, and / or an antiandrogenic substance are also claimed.
Owner:JENNINGS SPRING BARBARA L
Extraoral Nasal Molding Headgear Device for the Treatment of Cleft Lip and Palate
InactiveUS20150164676A1Direct contact guaranteeEasy to fixSurgeryDilatorsNasal cavityIncomplete bilateral cleft lip
The present invention is a device for pre-surgical treatment of cleft lip and cleft palate. The device is extraoral thus reducing the risk associated with existing devices and technologies that are intraoral, such as, for example utilizing a Nasoalveolar Molding (NAM) appliance. The adjustable extraoral nasal molding appliance of the present invention consists of an adjustable and securable head fastener, a front connector with a forehead rest pad, a rod support having an aperture through which a rod is slidably connected, a fastener for locking a rod in a set position, the rod, a spring and at least one nasal bulb. Different shaped springs can be attached for treating unilateral as well as bilateral cleft lip and palate patients. Different nasal bulbs can be attached for treating unilateral as well as bilateral cleft lip and palate patients.
Owner:KIM BERMAN HERA
Automatic recognition method for pharyngeal fricative in cleft palate speech based on PICGTFs and SSMC enhancement
ActiveCN109300486AThe test results are objective and accurateRealize automatic measurementSpeech analysisSignal classificationGammatone filter
The invention discloses an automatic recognition method for pharyngeal fricative in cleft palate speech based on PICGTFs and SSMC enhancement, which relates to the field of speech signal processing. The method uses piecewise index compression Gammatone filters PICGTFs to carry out filter processing on the speech, a speech signal spectrogram in each channel is subjected to enhancement processing based on a SSMC (Softsign-based Multi-Channel) model and a DoG (Difference of Gaussian) model, a feature vector is extracted from the enhanced spectrogram respectively and put to a KNN classifier for pattern recognition to determine whether to belong to the pharyngeal fricative, and the same classification result is taken as a final recognition result of the algorithm. The method makes full use of the differences between the pharyngeal fricative and the normal speech in frequency domain distribution of spectral energy, and in comparison with the prior art, the detection result is objective and accurate, high-degree automatic measurement is realized, reliable reference data are provided for clinical digital evaluation of the pharyngeal fricative, the development needs of precise medical treatment are met, and more accurate and effective signal classification and recognition can be carried out.
Owner:SICHUAN UNIV
Tissue engineering bone for repairing cleft palate defect of maxillofacial region and preparation method
InactiveCN113349988AReturn to normal structureRecovery functionBone implant3D printingJaw boneNormal growth
The invention discloses a tissue engineering bone for repairing a cleft palate defect of a maxillofacial region and a preparation method. The tissue engineering bone comprises a double-layer porous scaffold and hydrogel, wherein pores of the scaffold are filled with the hydrogel. The double-layer degradable tissue engineering bone prepared by the preparation method is completely matched with the cleft palate defect of a patient, and can accurately restore the original palate structure and function of the patient, so that a series of problems such as donor site trauma, malformation, scars and pain caused by current autogenous bone transplantation and inevitable defects such as limited sources are avoided; and meanwhile, the tissue engineering bone is degradable, so that normal growth and development of the jaw bone are not affected.
Owner:ZHEJIANG UNIV
Recognition method of cleft palate speech nasal leakage based on recursive graph analysis
InactiveCN109215633AThe test results are objective and accurateRealize automatic measurementImage enhancementImage analysisPattern recognitionSignal classification
The invention discloses a recognition method of cleft palate speech nasal leakage based on recursive graph analysis, which relates to the field of speech signal processing. The detection method comprises the following steps: (1) preprocessing the speech signal, downsampling the input speech signal, and performing normalizing framing, pre-emphasis and amplitude normalization; (2) obtaining a recursive graph and a matrix recursive graph of the speech signal after the preprocessing; (3) performing trend analysis of recursive graph; (4) directly dividing the region into blocks for recursive graphand performing matrix processing for recursive graph; (5) performing image processing on the recursive image, and subjecting the image matrix after format conversion to binarization processing and filtering with two special structure templates in turn; (6) classifying and recognizing the signal by using classifier to obtain an automatic recognition result. Compared with the prior art, the detection result is objective and accurate, realizes a higher degree of automatic measurement, provides reliable reference data for the clinical digital evaluation of cleft palate speech nasal leakage, meetsthe development needs of precision medicine, and performs more accurate and effective signal classification and recognition.
Owner:SICHUAN UNIV
Nursing device
InactiveUS8568352B2Minimize the possibilityLarge containersOral administration deviceCouplingDisplay device
Owner:AL THALAB FATEMAH S
Method and devices for the treatment of nasal sinus disorders
Methods and devices for facilitating the treatment and repair of nasal sinus afflictions utilizing devices that are positioned within proximity of the nasal sinus and the afflicted location. The methods and devices are particularly beneficial for the treatment of sinusitis, broken noses, sleep apnea, cleft palates and deviated septums. In addition, the devices may enhance and expedite patient recovery and reduce or mitigate bleeding.
Owner:MISCHE HANS A
Soft palate morphology and development detection method
InactiveCN108175431AThe detection method is simpleSimple methodRadiation diagnostic clinical applicationsCleft palate repairCleft palates
The invention belongs to the field of medicine soft palate detection, and particularly relates to a soft palate morphology and development detection method. The method is characterized by comprising the following steps of preparing equipment, performing cephalometrics and side position photographing, performing cephalometrics pronouncing side position photographing and performing contrastive analysis on images photographed two times in a PACS, and detecting the soft palate morphology and the lifting height and the velopharyngeal closure condition of the soft palate during pronunciation. Due totwo-time cephalometrics side position exposure, after contrastive analysis, the soft palate morphology and development conditions of an examinee can be displayed, and references can be provided for velopharyngeal closure research and soft palate morphology rebuilding in cleft palate repairing to a certain extent.
Owner:SICHUAN UNIV
Use of tamoxifen and a method for constructing a cleft palate animal model
InactiveCN108938613BEliminate distractionsOrganic active ingredientsAnimal husbandryObstetricsPhysiology
The invention especially relates to application of tamoxifen and a method for constructing a cleft palate animal model, belonging to the field of genetic engineering technology. Research results of the invention show that a female mouse (Tgfbr1<f / f>K14Cre+) is mated with a male mouse (Tgfbr1<f / f>K14Cre-), or a female mouse (Tgfbr1<f / f>K14Cre-) is mated with a male mouse (Tgfbr1<f / f>K14Cre+), and Tgfbr1 gene knockdown can be performed on a fetal mouse thereof under the induction of tamoxifen; so the cleft palate animal model is constructed. In the mouse constructed by using the method of the invention, Tgfbr1 genes in palatal epithelial cells are knocked out, and interference of other factors in the cleft palate model is reduced.
Owner:BEIJING STOMATOLOGY HOSPITAL CAPITAL MEDICAL UNIV
Hand and foot chapped ointment for reducing swelling, relieving pain, relieving itching, nourishing skin and preparation method thereof
ActiveCN107441340BReduce harmSmall side effectsCosmetic preparationsToilet preparationsCelluloseApple peel
Owner:上海麦坤特医药科技有限公司
A urea-vitamin e cream for treating chapped hands and feet and chapped hands and feet caused by keratotic tinea pedis
ActiveCN105997989BFine and uniform particle sizeGood spreadabilityAerosol deliveryOintment deliveryPolyethylene glycolSoft cleft palate
The invention relates to urea and vitamin E cream for treating hand and foot rahagades and rahagades caused by keratotic tinea hand or pedis. The cream contains urea, vitamin E, catechinic acid and polyoxyethylene-7-stearate. The fine cream with small and uniform particle size and good coating property can be prepared through low-speed stirring. The cream has higher high temperature stability, and oil-water layering does not occur easily. The cream is suitable for industrial production, production processes are simplified, energy is saved, and stability is higher.
Owner:上海正大通用药业股份有限公司
A kind of acellular allogeneic dermal matrix and its application in oral diseases
ActiveCN108144124BNo immune rejectionSoft textureTissue regenerationProsthesisNasal passagesOral mucous membrane
The invention relates to application of an allograft acellular dermal matrix in oral diseases, in particular to application of the allograft acellular dermal matrix in the repairing of cleft lip and / or alveolar cleft, cleft palate and oral mucous membrane defect, the repairing of periodontal defect and gingival recession, the repairing of nasal mucosa, tooth implantation, the repairing of furcation involvement and the prevention of complications such as dry socket after impacted tooth extraction, and belongs to the technical field of biological medical material tissue engineering. The allograft acellular dermal matrix is a product improved by a process, the mechanical performance of the product is suitable for surgery, and the sewing strength of the product is 16-18N; the allograft acellular dermal matrix is free of immunological rejection, capable of fast inducing tissue regeneration, soft in texture after implantation, free of contour feeling and good in in-vivo compatibility and hasa stable stent and template effect.
Owner:BEIJING JAYYALIFE BIOTECH CO LTD
A method and system for automatic segmentation of consonants and finals in cleft palate speech
The invention discloses a cleft palate speech initial and final automatic segmentation method and a cleft palate speech initial and final automatic segmentation system, which relate to the field of speech signal processing technologies, especially a cleft palate speech initial and final automatic segmentation technology. The invention aims to provide an initial and final automatic segmentation algorithm for cleft palate speech to solve the technical problem that an initial and final automatic segmentation algorithm for the cleft palate speech does not exist in the prior art. The cleft palate speech initial and final automatic segmentation method is characterized by carrying out the processing steps on a syllable including an initial: a quasi voiced initial and a quasi voiceless initial distinguish step, which is used for distinguishing whether the syllable is a syllable comprising a quasi voiced initial or one comprising a quasi voiceless initial; an initial and final segmentation step for the syllable comprising the quasi voiced initial; and an initial and final segmentation step for the syllable comprising the quasi voiceless initial.
Owner:SICHUAN UNIV
Cleft palate surgery training simulator
The invention discloses a cleft palate surgery training simulator. The cleft palate surgery training simulator comprises a cleft palate simulating unit, a tray, an angle adjusting mechanism and a base, wherein the curved surface shape of the outer surface of the tray simulates the curved surface shape of a human face; the tray is provided with an accommodating cavity at a position simulating the mouth and nose of the human body; the overall structure of the cleft palate simulating unit simulates the structure of the mouth and nose of the human body; the cleft palate simulating unit is made ofan elastic material; a gap simulating cleft palate is formed on the cleft palate simulating unit; the cleft palate simulating unit is placed in the accommodating cavity in order that the tray and thecleft palate simulating unit construct a structure capable of completely simulating the curved surface shape of the human face; the base is positioned below the try; the tray is arranged on the base through the angle adjusting mechanism; and the tray can rotate by a preset angle relative to the base through the angle adjusting mechanism.
Owner:四川康铭智能装备科技有限公司 +1
A kind of method and application of mouse loxl3 gene conditional knockout
ActiveCN104651400BMicrobiological testing/measurementVector-based foreign material introductionDiseaseEmbryo
The invention relates to a method for conditional knockout of Lox13 gene of a mouse and an application. The method comprises the steps that loxP loca of a Cre recombinase targeting sequence are added to the two ends of a key exon of an Lox13 gene; a conditional gene knockout carrier is constructed, and transfected with an embryonic stem cell (ESC); microinjection is conducted for making a floxed mouse capable of being used for conditional gene knockout; the floxed mouse is mated with a Cre mouse with corresponding tissue specificity; and the mouse of which an Lox13 gene can be knocked out at a specific tissue is obtained. The mouse obtained by the method serves as a model mouse for morbidity research on a cleft palate disease, so that the functions of the Lox13 gene in the tissue and the effects of the Lox13 gene in an embryonic development regulation mechanism can be illustrated in details. In addition, the mouse can serve as an animal model for researching the functions of the Lox13 gene, and has important application values.
Owner:SHANDONG UNIV
Traction device used in oral cavity for treating cleft palate made of nickel-titanium memory alloy
A NiTi memory alloy type internal palatoschisis tractor is composed of a palatal steel supporter whose surface is matched with the palatal mucosa, a fixing belt ring fixed to the external side of saidpalatal steel supporter and surrounding on molar teeth, and a curved NiTi memory alloy bar fixed between said palatal steel supporter and palatal bone.
Owner:KUNSHAN TRADITIONAL CHINESE MEDICINE HOSPITAL +1
Plastic appliance digitalizing method of cleft palate alveolar bone
InactiveCN102169519BHigh precisionRealize individual precise designSpecial data processing applicationsShape changeNon invasive
The invention belongs to a non-invasive treating method of congenital cleft palate in the medical field, especially relating to a shape appliance digitalizing method of a cleft palate alveolar bone, which comprises the following steps of: 1) obtaining the jaw arch fault information of a cleft palate alveolar bone by using the microscopic CT (computed tomography) technology, wherein the thickness of a scanning layer is 50 mu m; 2) moving the cleft palate alveolar bone segment of a maxillary arch solid model to approach to a normal maxillary arch form from an abnormal form in a simulation manner in reverse engineering software, and simulating and demonstrating the shape change process step by step; 3) obtaining a digitalized model of the cleft palate alveolar bone jaw arch in each stage in the process of remedying according to the simulation and demonstration; 4) manufacturing an appliance retention column digitalized model used in each stage of shaping the alveolar bone according to the digitalized model of the cleft palate alveolar bone jaw arch; and 5) automatically processing a prototype of an alveolar bone shape appliance by using the rapid forming technology. A digitalized designing and manufacturing method of the shape appliance of a cleft palate alveolar bone independent of the experience and handwork of a doctor is provided.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY
Method for preparing congenital cleft palate animal model
PendingCN108606968AReliable methodLarge operating rangeOrganic active ingredientsDiseaseDexamethasone
The invention provides a method for preparing a congenital cleft palate animal model, and relates to the field of animal models of oral diseases. The preparation method comprises the following steps:pregnant rabbits are treated with dexamethasone for intervention every day for 13 days to 16 days of pregnancy, the pregnant rabbits are fed to production, and offspring rabbits are congenital cleft palate models. The method can efficiently construct the morphologically stable congenital cleft rabbit model, thereby providing a model basis for further clinical research of cleft palate.
Owner:SICHUAN UNIV
Three-dimensional culture method of palatal organs in vitro
The invention discloses a three-dimensional culture method for palatal organs in vitro. The whole tissue from the inferior orbital edge to the corner of the mouth is taken from the embryonic palate in the early stage of development or in the developmental stage, embedded in a hydrogel support, and culture solution is added for three-dimensional culture. It can provide a three-dimensional growth environment similar to the body, avoid the use of expensive materials and processes, and has the advantages of simple operation and low cost. In addition, the biological characteristics of the palatal plate tissue can be adjusted by changing the composition of the hydrogel scaffold, which is suitable for different stages of embryonic development The tissue culture of normal and abnormal palate plate can be used for the study of the formation mechanism of cleft palate and the screening of drugs that promote the formation of palate plate.
Owner:DALIAN MEDICAL UNIVERSITY
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