36 results about "Croton oil" patented technology

The invention discloses the eugenic nanometer drug, comprising isopropyl microstate, croton oil, vitamin E oil, tuwen-80, spans-80 and eugenic. The drug has the advantages of improving the antibiosis, anti-inflammation, disinfection, analgesic, and ant parasitic. So the drug is green, safe and highly effective ant parasitic agent.

The invention relates to an insecticide and a preparation method thereof, particularly a botanical insecticide and a preparation method thereof. The insecticide is mainly prepared from the following Chinese herbal medicine protophyte extracts in percentage by weight: 50-75% of tobacco leftover, 2-5% of croton oil, 2-5% of Melia toosendan, 2-5% of wild chrysanthemum flower, 2-5% of pod pepper, 5-10% of arum, 5-10% of gingko exopleura and 5-10% of derris, wherein the tobacco leftover comprises the following components in percentage by weight: 64% of tobacco leaf, 18% of tobacco stem, 13% of tobacco root and 5% of tobacco flower. The invention has the following advantages: 1. the comprehensive insecticidal rate is high; 2. the application isolation period reaches about 15 days, thereby lowering the agricultural production cost; 3. no three wastes are produced in the production process, residues used as the fertilizer can be used for killing insects, the insect control rate for Chinese chive maggots is up to 95%, and the residues can also relieve sealing of soil and loosen the soil; and 4. no insecticide remains on crops.

An agricultural chemical used as insecticide and bactericide is prepared from azedarachin, croton oil, limonene and carrier. Its preparing process and application are also disclosed.

The invention discloses a hydrolysable tannin compound, which is formed by connecting glucose and gallic acid by ester bond or glycosidic bond. According to the number of composing sugar, the compound falls into monomer, dimer and trimer hydrolysable tannin derivatives, the hydrolysable tannin compound is characterized in that the end group of soup is free hydroxyl group. Animal experiments prove that the hydrolysable tannin compound can inhibit croton oil induced mouse ear swelling and carrageenin induced mouse foot swelling, has obvious inhibitory activity on type II collagen induced DBA-1 type mouse arthritis, and can be used for prevention and/or treatment of rheumatism and rheumatoid arthritis.

The invention discloses botanical insecticide and a preparation method thereof. The botanical insecticide comprises the following raw materials in parts by weight: 65 to 76 parts of toosendanin original liquid, 2 to 5.2 parts of croton oil original liquid, 4.5 to 7 parts of limonene original liquid, 8 to 13 parts of dimethyl sulfoxide, 4.5 to 10 parts of organic silicon surfactant and 0.4 to 0.8 part of plant emulsifier. The preparation method comprises the following steps: S1, weighing the toosendanin original liquid, the croton oil original liquid, the limonene original liquid, the dimethylsulfoxide, the organic silicon surfactant and the plant emulsifier according to the formula quantity; S2, adding the toosendanin original liquid, the croton oil original liquid and the limonene original liquid weighed in the step S1 into an emulsifying machine, slowly adding the organic silicon surfactant and the plant emulsifier in the emulsification process, and stirring and emulsifying for 15 to 30 minutes to obtain the botanical insecticide. The botanical insecticide provided by the invention has efficient broad-spectrum insecticidal and antibacterial effects, significant insecticidal effect and low toxicity, can be naturally degraded and avoids residue.

The invention relates to an antibacterial and antiviral Chinese medicine compound preparation and a preparation method thereof. The antibacterial and antiviral Chinese medicine compound preparation comprises eight Chinese medicines: radix puerariae, radix bupleuri, herba ephedrae, radix paeoniae alba, radix platycodonis, liquorice root, Chinese date and ginger. The preparation method comprises the following steps: soaking the radix puerariae, radix bupleuri and herba ephedrae with warm water for half an hour; adding water to the soaked radix puerariae, radix bupleuri and herba ephedrae and other medicines; performing concentration and concentrating the extracted liquid into extractum; and adding auxiliary materials to prepare granules. Ni vitro tests indicate that the antibacterial and antiviral Chinese medicine compound preparation provided by the invention has obvious effects in inhibiting and killing bacteria and viruses; and animal tests indicate that the antibacterial and antiviral Chinese medicine compound preparation has obvious effect in clearing heat for rat fever caused by yeast, can obviously suppress mouse ear swelling caused by croton oil, and has obvious function of consolidating exterior and easing pain.

The invention discloses a toosendanin-containing pesticide composition and a preparation method thereof. The toosendanin-containing pesticide composition comprises a toosendanin solution, croton oil,limonene, an organosilicon surfactant SilwetL77 and a vegetable oil emulsifier. The toosendanin-containing pesticide composition product has a good slow release effect, and is prepared by compoundinga toosendanin solution, croton oil, limonene, an organosilicon surfactant SilwetL77 and a vegetable oil emulsifier; the product has the advantages of obvious compounding interaction, long action time,obvious insecticidal effect and low toxicity, can be naturally degraded, and reduces the drug resistance of pests; toosendanin in the toosendanin solution and crotonic acid in crotonic oil are botanical pesticides, do not contain any chemical pesticide component and have no residue. According to the toosendanin solution preparation method, the toosendanin extraction efficiency is 3-5 times that of a common method, the production efficiency is greatly improved, the impurity content in the prepared toosendanin solution is greatly reduced, and the purity is high.

The invention relates to the synthesis of an emodin compound illustrated in the formula (I), and the application of the compound in antimicrobial and anti-tumor agents. The result of the in-vitro antibacterial activity test shows that, a synthesized emodin derivative is strong in antimicrobial activity for methicillin-resistant staphylococcus aureus ATCC25923, escherichia coli ATCC25922, Pseudomonas aeruginosa ATCC27853, and helicobacter pylori. Therefore, the synthesized emodin derivative can be used for preparing antibacterial agents. The result of the in-vitro anti-tumor activity test shows that, the synthesized emodin derivative is strong in anti-tumor activity. Through exploring the influence of the emodin derivative on the croton oil-caused auricular swelling condition of mice, the above compound is good in anti-inflammatory activity. The chemical structural formula of the above emodin derivative is illustrated in the formula (I) as follows, wherein R1, R2 and R3 are defined in the specification.

The invention discloses a traditional Chinese medicine composite for resisting tumor and adjusting immunity, a preparation method thereof and application thereof in preparing medicament for resistingtumor and adjusting immunity. The traditional Chinese medicine composite consists of croton cream, balloon flower and the bulb of fritillary proportioning 1:3:3, and is characterized in that in the croton cream composition, content of croton oil accounts for 8-12% of the total weight of the croton cream, and content of crotonoside accounts for 1.47-5.59% of the total weight of the croton cream. The croton cream is prepared according to the following preparation method: separating and extracting croton oil from croton kernel to respectively obtain croton dreg and croton oil; then adding proportioned croton oil into croton dreg, and grinding evenly. The invention employs modern cell and molecular biology and other experiment means, overcomes defects of modern technologies, and effectively destructs toxalbumin in croton cream and adjusts content of croton oil when guaranteeing medicinal activity for efficacies of resisting tumor and adjusting immunity of the ancient prescription of threewhite medicinal powder, thus ensuring curative effect and having higher safety.

The invention discloses a croton oil detection reagent. The croton oil detection reagent comprises the following components in parts by weight: 38-42 parts of absolute ethyl alcohol, 12-18 parts of sodium hydroxide solution, 3-8 parts of petroleum ether and 2-6 parts of dioxyacetone. The croton oil detection reagent has the beneficial effects that the detection rate of the croton oil detection reagent is higher than that of similar products by 25-40%; meanwhile, the croton oil detection reagent is simple to operate, intuitive in detection effect and quick in detection speed.

The present invention relates to a croton processing method for treatment of tuberculosis, and specific relates to a high temperature processing attenuation method of a traditional Chinese medicine croton and the role thereof in the treatment of tuberculosis. The croton processed product is obtained through three methods of high-temperature stir-frying, high temperature baking, and microwave heating. The processed croton has no toxic protein detected. LD50 increases significantly. The relative content of each component in the croton is essentially unchanged, and the croton oil content is relatively elevated. The processed croton is mixed with other traditional Chinese medicines to make pills which have significant role in resisting mycobacterium tuberculosis in vitro and in vivo. The croton processing method for treatment of tuberculosis disclosed by the invention has effects of reducing toxicity and enhancing efficacy, and has very prominent advantages compared with conventional croton processing methods such as baking, boiling, steaming, etc.

The invention relates to the technical field of natural medicine extraction, and particularly discloses a method for extracting phorbol from croton oil by using a Girard's reagent. The method comprises the following steps: S1, mixing 1 part of croton oil with 5-25 parts of a methanol saturated solution of a Girard's reagent according to a feed liquid volume ratio, and carrying out a stirring reaction at 18-50 DEG C for 30-180 min to obtain a reaction solution; S2, concentrating a reaction solution; S3, extracting and removing croton oil by using petroleum ether to obtain a water phase containing the phorbol Girard's reagent salt; S4, adjusting the pH value to 2-3, and extracting the phorbol in the water phase by using petroleum ether; S5, concentrating the petroleum ether phase to obtain an oily substance; and S6, carrying out alcoholysis, acidification and filtration on the oily substance to obtain a crude product of the phorbol. According to the method, carbonyl reacts with a Girard's reagent, and then a large amount of impurities can be removed by an extraction method due to different polarities of the components, so that a crude product of the phorbol with relatively high purity is obtained. The method has the characteristics of simplicity and convenience in operation, short time consumption and low solvent consumption, and is easy to popularize and apply industrially.

The invention relates to a processing method of croton for treating tuberculosis, in particular to a high-temperature processing and attenuation method for traditional Chinese medicine croton and action thereof on treatment of the tuberculosis. The croton is processed through three methods of high-temperature frying, high-temperature roasting and microwave heating to obtain a croton processed product. In the processed croton, toxic protein is not detected, LD50 is obviously increased, the relative content of each component in croton oil is basically kept unchanged, and the croton oil content is relatively increased. After being combined with other traditional Chinese medicines to prepare pills, the processed croton has an obvious anti-tuberculosis bacillus effect in vivo and in vitro. Theprocessing method of the croton for treating the tuberculosis disclosed by the invention has the effects of reducing toxicity and enhancing therapeutic effect; and compared with the conventional croton processing methods of roasting, boiling, steaming and the like, the processing method has the advantages of prominent advantages.