According to the natural gas distributed energy region user cooling, heating and power load prediction method and system provided by the invention, on the basis of the climate characteristics of the target region and various urban functional buildings, the hourly cooling, heating and power load of the standard building model of each region is obtained through simulation calculation, so that in thenatural gas distributed energy system design and planning stage, according to the proportion of standard buildings in regional users, hourly cooling, heating and power load characteristics of the regional users are effectively predicted, accurate and reliable regional user load prediction data can be provided in the design and planning stage of the natural gas distributed energy system, and on the basis, an improved configuration scheme and an optimized operation strategy of the energy system are studied; and the advantages of high efficiency, economy, environmental protection and reliabilityof the distributed energy system are fully achieved.