39 results about "Limb bones" patented technology

The invention discloses a preparation method of a bone peptide solution and belongs to the field of biological engineering. The preparation method comprises the following steps: (1) crushing fresh limb bones of an animal, performing decompression extraction and ultrasonic treatment in a reaction kettle, extracting a concentrated solution and separating solid from liquid to obtain filtrate; (2) digesting by enzymolysis, namely respectively adding protease into the concentrated solution to perform enzymolysis; (3) heating the enzymolysis solution to realize enzyme deactivation, performing ultrafiltration and collecting ultrafiltrate to obtain the bone peptide solution. By crushing cells by adopting decompression extraction with assistance of ultrasonic wave, the extraction rate is increased; the method disclosed by the invention has the advantages of improving the degradation efficiency by adopting an enzymolysis method for production, reducing use of a great amount of acid, alkali and the like in a general extraction method, retaining active polypeptide in the bone peptide better and improving the product quality. The bone peptide product prepared by the method disclosed by the invention is good in quality, high in rate of finished products, remarkable in treatment effect, easy to operate and suitable for industrial production.

Disclosed is a dinosaur model with multi joint assembly that allows the user to grow creative idea and pursue self-lead learning during the assemblage of relatively many parts into the finished article and which is designed to allow free modification of actions and to provide a definite anatomical structure of dinosaur during the sequential assembly of a skeletal frame. It comprises: a skeletal frame in which skull, cervical vertebra, trunk skeleton, and tail bone units are sequentially connected through joints and the trunk skeleton unit is articulated with limb bone units; an integumental frame, responsible for appearance, comprising head integument, neck integument, trunk integument, tail integument, and limb integument units that are associated with the skull, the cervical vertebra, the trunk skeleton, the tail bone, and the limb bone units, respectively; and a connection member, intercalated between the skeletal frame and the integumental frame, for connecting the frames each other.

A limb bone joint rehabilitation training device comprises a power structure, the upper end of the power structure is connected with a limb training structure, and the limb training structure comprises an upper limb joint training assembly capable of conducting arc-shaped reciprocating rotation and reciprocating autorotation twisting on hand joints of a patient and a lower limb joint training assembly connected with the upper limb joint training assembly. The lower limb joint exercise assembly can perform up-down bending and stretching exercise and left-right opening and closing exercise on leg joints of the patient; the front end of the power structure is connected with a transmission structure, and the transmission structure is connected with a lumbar vertebra massage structure capable of conducting circumferential rotation and intermittent up-down protruding massage on the two side edges of the lumbar vertebra of a patient. The transmission structure is further connected with a cervical vertebra joint massage structure which can circularly extrude and massage different positions in front of and behind the cervical vertebra of the patient and automatically adjust the extrusion force, and the problems that a rehabilitation exercise device in the prior art is single in structure and cannot fully arouse the enthusiasm and autonomy of the patient in use are effectively solved.

The invention discloses a limb bone cutting navigation device capable of realizing accurate locating, and belongs to the field of medical equipment. The device is assembled with a locator and a bone cutting guide plate. The locator is provided with a plurality of metal locating sheets. The bone cutting guide plate includes a first substrate, a second substrate, and a bridging plate connecting the first substrate and the second substrate from above. The first substrate is provided with an anti-twisting pile matching an anti-twisting hole of the locator. The bone cutting guide plate is of an assembled structure, so that the bone cutting guide plate can cooperate with medical equipment in accurate locating. Consideration is given to both financial cost and the locating flexibility and accuracy in shape design of the locator. The bone cutting guide plate ensures the accuracy and security of nail implanting and knife advancing from multiple aspects.

The invention provides a limb bone segmentation method and device, an electronic device and a readable storage medium, and relates to the field of medical image processing. The method comprises the steps of performing image preprocessing on a to-be-segmented limb DR image when the to-be-segmented limb DR image is obtained; obtaining a target limb DR image, using a first skeleton segmentation modelto carry out skeleton region identification and image segmentation on the target limb DR image; obtaining a skeleton distribution area of the target limb DR image; performing image cutting on the target limb DR image according to the bone distribution area; obtaining a limb foreground image corresponding to the bone distribution area; and finally, carrying out limb bone category identification and image segmentation on each bone part in the limb foreground image by adopting a second bone segmentation model to obtain a segmentation image comprising a limb bone category distribution region of each bone part, thereby finishing high-precision image segmentation operation and obtaining a limb bone segmentation result with high segmentation precision.

A method for setting up 3-D model of human limbs includes shooting image series of human limbs postures and picking up mark point from them, confirming space 3-D coordinates corresponded by these marks then obtaining space 3-D position data of limb bone at each time, solving out corresponding deformation parameter and volume by equation with coordinate value as well as deformation parameter of rotation conical curve, and using ball and curve to draw out model of human limbs.

A compound bone peptide injection for treating rheumatic and rheumatoid arthritides, bone fracture, osteoporosis, cervical spondylopathy is prepared from scorpion and the limb bone of young ox through high-temp and-pressure extracting, depositing in alcohol and then in acid, heat treating, cold storage, ultrafiltration, further preparing, pouring in containers in N2 atmosphere, sterilizing and lamp examining.

The invention discloses a method for improving the cell compatibility of bio-derived hydroxyapatite. The method comprises: after freezing pig limb bones for three months at a temperature of -176 to -18 DEG C, removing soft tissues from the surface of the bone tissue, sawing the bone into loose bone blocks by using a bone saw, carrying out ultrasonic cleaning with purified water without organic solvents, removing the bone marrow components, placing in a freeze-drying machine, and carrying out freeze-drying; placing in a supercritical carbon dioxide reaction kettle, carrying out a reaction, taking out, placing in an alkali solution, carrying out freeze-drying, taking out, placing in a ventilation muffle furnace, and carrying out gradual temperature increase and decrease treatment; and packaging, and carrying out cobalt-60 gamma ray radiation sterilization to prepare the bio-derived hydroxyapatite. According to the present invention, the degreasing and protein removing treatment is performed with supercritical carbon dioxide so as not to produce the organic matter residue, such that the biocompatibility and the biomechanical properties of the prepared material can be effectively improved.

The invention discloses a chitosan / HA-based personalized cranial, maxillofacial and spinal repair material and a preparation method thereof. The repair material is prepared by taking a DCPD-CS mixed solution, lecithin, cholesterol and pectin as raw materials; the mechanical property of a chitosan material is effectively improved; the highest bending strength reaches 173 MPa; the highest bending modulus reaches 8.6 GPA; the repair requirements on bone defects in bearing parts such as the cranium, the maxillofacial region, the spine and the limb bones are met. The material is good in biocompatibility, is degradable and absorbable, and can remarkably induce repair and regeneration of the bone defects, the disadvantage of long-term retention in vivo of nonabsorbable materials such as titaniumalloy and PEEK is avoided, and the problems that absorbable materials such as PLA are liable to produce inflammatory reactions, the bone-forming effect is poor, and the like are also avoided. According to the chitosan / HA-based personalized cranial, maxillofacial and spinal repair material and the preparation method thereof, personalized design and manufacturing are performed according to CT scanning charts of the bone defect parts of patients; the cellular structure, pore diameter, porosity and the like of the material can be accurately controlled, and the matching between the degradation speed and the regeneration speed of different bone defect parts is realized.

The invention relates to a bone injury pulse current therapeutic apparatus and belongs to the technical field of medical apparatuses. The bone injury pulse current therapeutic apparatus comprises a support chassis and support legs, wherein universal wheels are arranged at the lower ends of the support legs; brake bars are arranged on the right sides of the universal wheels; brake blocks are arranged at the lower ends of the brake bars; support pillars are arranged at the upper end of the support chassis; a limb bone injury therapeutic apparatus is arranged above the support chassis; a support platform is arranged at the upper ends of the support pillars; a therapeutic apparatus master controller is arranged at the upper end of the support platform; a power switch is arranged at the front end of the therapeutic apparatus master controller; a therapeutic apparatus starting button is arranged on the right side of the power switch; a bone perspective starting button is arranged on the right side of the therapeutic apparatus starting button; a timed therapeutic button is arranged on the right side of the bone perspective starting button; the support platform is arranged at the upper ends of the support pillars. The bone injury pulse current therapeutic apparatus is simple in structure and convenient to operate, and can be used for helping the patients to recover quickly so as to decrease the pain of the patients, improve the rehabilitation efficacy and lighten the workload of the medical personnel.

The invention provides a limb bone movement simulation structure. A movable structure is connected between caput femur and pelvis or between scapula and humerus. The limb bone movement simulation structure is characterized in that the movable structure comprises an L-shaped plate, two perpendicular face plates of the L-shaped plate are respectively provided with shaft holes and shaft pins matched with the shaft holes. The shaft holes on one face of the L-shaped plate of a metal construction member are connected with the caput femur or the humerus through the shaft pins, and the shaft holes on the other face are connected with the pelvis or the scapula through the shaft pins to form the movable structure between the caput femur and the pelvis or between the scapula and the humerus and to form the simulation structure capable of simulating limb bone movements. The outer face portion of a bearing of the pelvis or the outer face portion of a bearing of the scapula is an arc face. A side portion of the other perpendicular face plate of the L-shaped plate is provided with a limiting boss which is movably matched with the arc face to control rotation angle between the femur and the pelvis or between the scapula and the humerus, and to simulate limitation of limb movements of a human body. The limb bone movement simulation structure is exquisite in structure, vivid in appearance, economic, applicable, and capable of well achieving the purposes of teaching and training.

The invention discloses a limb bone joint rehabilitation training device. The device comprises a supporting base, a first supporting frame, a second supporting frame, a rubber belt, a hydraulic rod and anti-skid protrusions. Four fixed seats are evenly distributed below the supporting base; pulleys are installed below the fixed seats; a first motor is installed in the middle of the left side of the first supporting frame; a rotating shaft is installed on the right side of the first motor; a fan is installed on the right side of the rotating shaft; and a plurality of through holes are evenly distributed in the right side of a protective cover; a transmission chamber is installed in the middle of the upper portion of the supporting base; the thread directions of the left side and the right side of a threaded rod are opposite; a transmission rod is installed above a threaded sleeve; a first mounting base is installed above the transmission rod; a supporting plate is installed above the first mounting base; a seat is installed on the left side above the supporting plate; a backrest is installed on the right side of the seat; and a hydraulic rod is installed on the right side above thesupporting plate. A pull ring and a foot training plate can conduct rehabilitation training on the hands and the feet of a patient respectively.

An orally taken composite osteopeptide medicine is prepared from the composite osteopeptide and cyclodextrin in mass ratio of 1: (4-7) through preparing composite osteopeptide from the limb bone of health pig or fetal calf, and scorpion, mixing cyclodextrin with purified water, adding said composite osteopeptide, stirring and vacuum drying at 45-60 deg.C to obtain included solid.

The method for diagnosing osteoporosis, using a method for determining the dynamics of closure of cavities to evaluate the effectiveness of the application of various bone protectors, relates to the field of medicine, for the diagnosis of osteoporosis and measurement of the effectiveness of therapeutic and prophylactic treatment of conditions associated with osteoporosis. The method is characterised by laboratory, histological and radiological methods of examination (standard radiography) and by measuring bone mineral density using the radiological absorptive method on osteometers, into which an additional diagnostic criterion is introduced, namely the measurement of cavities by specially adjusting them to measure cavities in trabecular bone sections using the radiological absorptive method and in addition, distilled water is introduced into special incubation apparatuses around the limb bones of the hands and feet which are being examined. The problem being addressed by the claimed invention is to objectively evaluate the effectiveness of a preparation (preparations) (bone protector) and measure cavities in trabecular bone sections. It proposes to improve the diagnostic capabilities of computerised osteometers by measuring cavities caused by osteoporosis and determine the severity of the disease not only on the basis of mineral density, but also on the basis of the presence of cavities in trabecular bone sections.

The invention discloses a preparation technology for a bone peptide glucose injection. The injection is prepared from adding a certain proportion of glucose on the basis of a bone peptide raw materialliquid; the bone peptide raw material liquid can be prepared from performing hot pressing extraction, concentration, alcohol precipitation, acid-base precipitation and ultrafiltration on limb bones of pigs; and adding the glucose in proportion, and diluting the mixture with injection water so that the injection can be prepared. The injection consists of the bone peptide raw material liquid, the glucose and the injection water; and each 100 ml of the injection contains 50-100 mg of the bone peptide raw material liquid (by polypeptide) and 5 g of the glucose. Thus, a process that a bone peptideinjection is temporarily dissolved in a glucose solution during intravenous drip in the past can be simplified, convenient clinical use can be realized, efficiency can be enhanced, and the probability of drugs being polluted can be reduced; and the injection can be used for promoting fracture healing.

The invention belongs to the technical field of specimen preparation, and particularly relates to a method for removing soft tissues from a canine bone specimen. The method comprises the steps: removing large muscles attached to a skeleton, and dividing the skeleton into a skull, a spine, limb bones, a sternum and ribs; preparing alkaline protease solutions with the concentrations of 0.3% and 0.5%; putting the skull, the limb bones and the chest ribs into 0.3% alkaline protease solution, and respectively soaking in a constant-temperature incubator at 50 DEG C for 36 hours, 66 hours and 60 hours; putting the spine bone into a 0.5% alkaline protease solution, and soaking in a 50 DEG C constant-temperature incubator for 60 hours; and taking out the bone and washing with water. After the softtissues are removed by the method, the prepared specimen is complete in bone and less in residual grease of the bone, and the prepared specimen is white in bone color.

The invention relates to a method for efficiently separating and culturing mesenchymal stem cells of a primarily-cultured rabbit, which comprises the specific steps of: executing an experimental animal by pumping air embolism and then soaking for 15-20min with alcohol for sterilizing, placing in a clean bench for separating limb bones, shearing two ends of the bones after repeatedly washing with a PBS (Phosphate Buffer) and DMEM (Dulbecco's Modified Eagle Medium) culture solution, and washing marrow cavities with the DMEM solution containing heparin with concentration of 625U / ml; respectively filtering marrow liquids obtained from the step 1 by using syringes with different diameters, preparing a monoplast suspension and then slowly injecting into an eccentric pipe containing isovolumetric Percol 1 for centrifuging for 20min, collecting an intermediate cloud cell layer, washing cells with an LG-DMEM solution, centrifuging for 5min, repeatedly washing for 2-3 times, adding the washed cells to the LG-DMEM solution containing a proper proportion of double antibodies (1%) and comprising 10% fetal calf serum, blowing and beating to form a cell suspension, counting and regulating the cell density to 1*10<8> / L, inoculating in a 25cm<2> plastic culture bottle, and placing in a culturing box with conditions of a temperature of 37 DEG C and a humidity of 5 percent for culturing. The invention can be effectively, conveniently and efficiently separating and culturing the mesenchymal stem cells of the primarily-cultured rabbit and is prepared for further basic experiments and clinical research.

The invention discloses an elasticity modulus determination method and preparation method of an individualized limb bone fracture setting internal fixation device.The elasticity modulus determination method comprises the steps that CT scanning is performed on a target limb bone, a three-dimensional model is rebuilt, the material attributes are given to the target limb bone, a finite element analysis model is built, and an elasticity modulus gradient distribution rule is obtained through analysis; the internal fixation device is drawn according to the operation requirements, and the elasticity modulus of the internal fixation device is obtained by aiming at the assembly relationship between the fracture part of the limb bone and the internal fixation device, combining the elasticity modulus gradient distribution rule and adopting an interpolation method.According to the elasticity modulus determination method and preparation method of the individualized limb bone fracture setting internal fixation device, internal individualization and external individualization are both achieved, the internal fixation device is externally fit with the human body limb bone and internally good in matching with the biomechanical characteristic of the individual bone, stress distribution of a steel plate and screws is more uniform and more reasonable, the stress shielding effect of an internal fixation material on the bone can be reduced, the compressing force of a fracture interface can be increased, the fracture heating fixation requirement is better met, and a scientific basis can be supplied to following research and development of a novel material, optimized design of an operation method and operative instruments and building of a relative database.

The invention discloses a porous hollow tubular material for regeneration, repair and reconstruction of large segmental bone defects in limbs, which is composed of a porous hollow tubular material with fan blades modified by coating, and the porous hollow tube with fan blades has excellent mechanical properties And highly biocompatible bioceramic, bioglass, bioglass-ceramic materials, the pore wall coating is composed of degradable highly active glass, ceramics or glass ceramics. The porous hollow tubular material of the present invention can be implanted into the broken end of a large segment of limb bone after debridement, which can provide durable mechanical support, prevent the intervention of various bacteria, fungi and other germs and microorganisms, and accelerate damage regeneration and repair, and has great advantages. Practical value.

The invention discloses an externally-applied traditional Chinese medicine emulsion for the prevention and treatment of knee osteoarthritis and a preparation method thereof. The externally-applied traditional Chinese medicine emulsion for the prevention and treatment of knee osteoarthritis is an O / W type dispersion, the average particle size of a dispersion phase is 0.5 micron, and the externally-applied traditional Chinese medicine emulsion is pharmaceutically named as a microemulsion preparation or a sub-nano emulsion preparation; and the externally-applied traditional Chinese medicine emulsion for the prevention and treatment of knee osteoarthritis is prepared from the following raw materials in parts by mass: 0.42 part of eucommia barks, 0.07 part of sangusis draconis, 0.25 part of fructus psoraleae, 0.07 part of buthus martensi karsch, 0.7 part of rhizoma drynariae, and 0.7 part of rehmanniae vaporata, and the content of Chinese medicinal materials in the finally prepared emulsion is 0.22%. The emulsion disclosed by the invention has the effects of nourishing liver and kidney, strengthening muscles and bones, and promoting blood circulation to remove meridian obstruction, and is suitable for treating orthopedic diseases such as limb bone arthralgia, neck, waist and leg pains and the like caused by the deficiency of liver and kidney and the stasis of tendons and vessels; and the emulsion can be applied to affected parts directly through the skin, and has a characteristic of remarkable drug effect.

The invention discloses a double-track type external fixed bracket and relates to an external fixed device in which limb bone fractures are not connected with bones. The double-track type external fixed bracket mainly comprises a power connecting rod with threads, a sliding connecting rod without threads, 4-6 sliding bodies and an ear-shaped body. During use, the double-track type external fixed bracket can apply the pressure, extend and three-dimensionally fix among bone sections in a multi-plane, thereby providing former fixation at early stage, fully avoiding the stress shielding effect atthe middle and later stages, according with the biological fixation and promoting the callus growth. The invention can be applied to the disconnection of limb bones, bone disconnection with bone defect and traumatic fracture including metaphysic fracture.

The invention discloses a chitosan / HA-based personalized cranial, maxillofacial and vertebral repair material and a preparation method thereof, which is prepared from a DCPD‑CS mixed solution, lecithin, cholesterol and pectin, and effectively improves the The mechanical properties of chitosan material, the bending strength is up to 173MPa, and the bending modulus is up to 8.6 GPa, which can meet the requirements of bone defect repair in the cranium, maxillofacial, spine, limb bones and other load-bearing parts. The material has good biocompatibility, can be degraded and absorbed, and can significantly induce the repair and regeneration of bone defects. It avoids the shortcomings of non-absorbable materials such as titanium alloy and PEEK that are stored in the body for a long time, and also avoids the inflammatory reaction of PLA and other absorbable materials. Poor bone formation and other issues. The present invention carries out personalized design and manufacture according to the CT scan of the patient's bone defect, and the microporous structure, pore diameter, porosity, etc. of the material can be precisely controlled, and the degradation speed can be matched with the regeneration speed of different bone defects.

The invention discloses a flexible transmission upper-limb exoskeleton robot for wearing, relates to a robot for wearing, and aims to solve such problems as low rigidity and weak loading capacity due to an upper-limb exoskeleton robot belonging to a serial connecting structure and caused incapability of safe and reliable life assistance for weak people. A wrist joint mechanism comprises a wrist joint driving fixed wheel, a human body palm fixed piece, a wrist joint moving wheel connecting piece, a wrist joint planet gear, a wrist joint driving rod, a wrist joint driving rod power input wheel, an exoskeleton front arm, an L-shaped connecting piece and a wrist joint steel wire rope; an elbow joint mechanism comprises an elbow joint planet gear, an elbow joint planet gear support frame, a first elbow joint driving fixed wheel, a second elbow joint driving fixed wheel, an elbow joint connecting upper arm frame, a U-shaped frame body and an elbow joint steel wire rope; and a shoulder joint mechanism comprises a shoulder joint planet gear, a shoulder joint driving fixed wheel, an exoskeleton support piece, a jack component, a shoulder joint driving fixed wheel connecting plate, a shoulder joint driving piece, an exoskeleton upper arm, a shoulder joint steel wire rope and an exoskeleton upper arm connecting shaft. The flexible transmission upper-limb exoskeleton robot for wearing is applied to the field of robot operation.

The invention relates to a load-variable upper limb assistance outer skeleton, in particular to a load-variable upper limb assistance outer skeleton based on the ditetragon gravity balancing principle. The problems that an existing upper limb outer skeleton is directly driven by a motor to achieve assistance, the volume and mass are large, a circuit is complex, reliability is reduced, and energy consumption is large are solved. The outer skeleton comprises two spring energy storage mechanisms, a back part, straps, two arms, two wrists, two rotating discs and a plurality of magnetic sensors. One end of each arm is connected with the upper portion of the corresponding side of the back part through the corresponding rotating disc. The other end of each arm is connected with the corresponding wrist. The straps are arranged on the front face of the back part. The magnetic sensors are sequentially arranged on the back face of the back part from top to bottom. The two spring energy storage mechanisms are arranged on the back part. Each spring energy storage mechanism is connected with the corresponding arm. The invention belongs to the field of medical apparatuses and instruments.

The invention provides a limb bone fracture fixing device for emergency treatment, and belongs to the field of limb bone fracture fixing. The limb bone fracture fixing device for emergency treatment comprises an adjusting mechanism and a fixing mechanism. The adjusting mechanism comprises a bracket, a support, a first connecting rod, a second connecting rod and a sliding rod; two first grooves are formed in the surface of the bracket at intervals; the threaded rod penetrates through one baffle in a threaded mode, the pressing plate is arranged between the two baffles, the supporting rod is supported between the hand supporting plate and the support, the two ends of the leg supporting plate are slidably connected to the sliding rods in a sleeving mode, a second groove is formed in the surface of the leg supporting plate, and an elastic band is installed on the surface of the leg supporting plate. The two ends of the elastic band are fixed to the two sides of the second groove. The limb bone fracture fixing device for emergency treatment can be used for fixing at different positions according to different injured positions, and can be turned over to serve as a dining table, so that the moving range of a patient is reduced, and the possibility that the patient is injured is reduced.