5 results about "Multiphoton excitation" patented technology

A manufacturing method of a resin component includes: providing a first resin member containing a polymer and a second resin member containing a polymer; and joining a first joining portion of the first resin member and a second joining portion of the second resin member to each other. The joining of the first resin member and the second resin member to each other includes irradiating the first joining portion of the first resin member with a laser light having a peak wavelength in a range from 350 nm to 420 nm is emitted in a presence of oxygen so as to cause multiphoton excitation of the first joining portion of the first resin member.

An apparatus for multiphoton parallel transmission for magnetic resonance imaging (MRI) of a subject, includes a radio frequency (RF) transmit coil, a single-channel universal excitation coil positioned outside of the RF transmit coil, and a processor device coupled to the RF transmit coil and the single-channel universal excitation coil. The RF transmit coil is configured to perform at least one RF excitation pulse of a multiphoton parallel transmit excitation comprising a multiphoton excitation pulse configured to correct spatial inhomogeneities and the single-channel universal excitation coil is configured to perform a low-frequency excitation pulse of the multiphoton excitation pulse. The processor device is configured to control current waveforms provided to the RF transmit coil to perform the at least one RF excitation pulse and to control current waveforms provided to the single-channel universal coil to perform the low frequency excitation pulse of the multiphoton excitation pulse.

Methods, systems and adaptors for multiphoton imaging of, and laser-tissue interactions with, non-transparent tissue, such as ocular and periocular tissue, are provided. Aspects of the present invention include methods of imaging a structure through non-transparent tissue, such as ocular or periocular tissue, comprising: deploying an excitation source to transmit light energy to a structure through non-transparent tissue, such as ocular or periocular tissue, detecting light emitted from the structure via multiphoton excitation through the non-transparent tissue, such as ocular or periocular tissue, and imaging the structure based on the detected light. Aspects of the present invention further include methods of treating tissue, such as ocular or periocular tissue or dermatologic tissue, by manipulating an imaged structure, including, for example, providing non-incisional therapy, photo-tissue interactions, multi-photon-mediated damage, such as thermal damage, photo-disruption, photo cross-linking, blood vessel coagulation or ablating tissue. Aspects of the present invention further include methods of imaging dermatologic tissues or providing dermatologic treatments. Aspects of the present invention further include methods of providing cosmetic treatments. Aspects of the present invention further include methods of guiding delivery of gene therapy or cellular therapy in ocular or periocular tissue. Also provided are systems and adaptors for performing the methods described herein.

A method for generating a magnetic resonance image of a subject using a magnetic resonance imaging (MRI) system includes receiving, using the MRI system, at least one parameter for a multiphoton parallel transmit excitation comprising a multiphoton excitation pulse configured to correct spatial inhomogeneities and performing, using the MRI system, a pulse sequence comprising the multiphoton parallel transmit excitation to acquire data from the subject. The multi photon excitation pulse of the multi photon parallel transmit excitation is performed using a radio frequency (RF) coil and a set of one or more shim coils of the MRI system. The method further includes generating, using a processor, an image of the subject using the acquired MR data. In some embodiments, the multiphoton excitation pulse includes an off-resonance RF excitation pulse performed using the RF coil and a plurality of low-frequency excitation pulses performed using the set of one or more shim coils. The plurality of low-frequency excitation pulses are performed simultaneously with the off-resonance RF excitation pulse.

A method comprising: providing a semiconductor body with a generation plane (4) and crystal lattice planes (6) intersecting the generation plane (4) at intersection lines (10); generating modifications (9) in the semiconductor body by multiphoton excitation, wherein the modifications (9) are spaced apart and alter a physical property of the semiconductor body to form subcritical cracks (12) in the generation plane (4); and separating a solid layer (2) from the semiconductor body by connecting the subcritical cracks (12) in the generation plane (4), wherein the generation of the modifications (9) in the semiconductor body by multiphoton excitation comprises: i) using a uniform polarization to form a first group of modifications (9) oriented in a first direction;and using a second polarization different from the first polarization to form a second group of modifications (9) oriented in a second direction different from the first, or ii) setting a polarization to form a group of modifications (9) such that the orientations of the modifications in the group differ from one another, or iii) setting a polarization for two or more groups of modifications (9) such that the modifications (9) of at least two of the groups have an orientation inclined to the lines of intersection (10).