6 results about "Roller Bottle" patented technology

The utility model discloses a multifunctional mining rolling bottle testing device which comprises a rolling bottle machine and a rolling bottle, the bottle rolling machine comprises an outer box body, an upper row of rollers, a lower row of rollers, an inflator pump, a refrigerating and heating temperature control device and a variable-speed motor, the upper row of rollers and the lower row of rollers respectively comprise four rollers, in the four rollers, the two rollers located in the middle are driving rollers, and the two rollers on the two sides are driven rollers; an upper-layer space and a lower-layer space which are isolated from each other are arranged in the outer box body, the upper-row rollers and the lower-row rollers are respectively arranged in the upper-layer space and the lower-layer space, and the upper-layer space and the lower-layer space are respectively provided with an independent inflator pump, a refrigerating and heating temperature control device and a variable-speed motor; the upper row of rollers and the lower row of rollers are respectively driven by two variable-speed motors to axially rotate; the inflation pump is connected with the rolling bottle through a detachable inflation accessory. According to the utility model, various types of rolling bottle tests can be realized.

This application discloses a novel cell culture roller bottle clamping assembly, relating to the field of cell culture technology. The invention includes a plate body with a limiting mechanism at its upper part and a fixing mechanism at its lower part. The limiting mechanism includes a support plate fixedly installed on the top surface of the plate body. A threaded rod is rotatably mounted on the bottom surface of the support plate and rotatably installed on the upper part of the plate body. A threaded block is threadedly fitted onto the outer surface of the threaded rod. By setting the limiting mechanism, the invention can clamp the neck of the roller bottle, thereby fixing the roller bottle and preventing it from shaking or even falling off if the clamping is too loose, thus improving safety. The fixing mechanism, with its clamping plate and the cooperation of the support plate and collar, provides better bottle fixation. Furthermore, the structure is simple and easy to maintain.

The utility model discloses a rotary bottle positioning detection mechanism which comprises a plurality of groups of small platforms, the plurality of groups of small platforms are arranged in a preset array, and the upper surfaces of the small platforms limit bottoms for receiving packaging bottles; the second power device drives the small platform to rotate in the circumferential direction of the small platform; and the label shooting photoelectric detection device is arranged corresponding to the small platform, and the labeling position of the packaging bottle is detected through the label shooting photoelectric detection device. The robot drives the clamp to place the round bottle on the small platform, the second power device drives the small platform to rotate, the round bottle starts to rotate along with the small platform, the labeling position is detected through the label shooting photoelectric device in the rotating process, and after the bottle rotates to the corresponding position, the second power device stops working; and the other robot drives the clamp to box the adjusted bottles, so that the labeling position is automatically adjusted, the production efficiency is improved, and the labor intensity is reduced.

The utility model belongs to the technical field of rolling bottle device, concretely relates to a cell culture is with rolling bottle device, including rolling bottle machine and the top surface of rolling bottle machine erects and installs rolling bottle frame, the bottom of rolling bottle machine outside wall is connected with fixed plate, the both ends of fixed plate's surface are connected with threaded rod through thread, the bottom of threaded rod is " convex " character shape, the bottom of threaded rod is provided with support foot, the top of support foot is connected with lug, the top surface of lug is provided with lug groove, the one side of the top of rolling bottle machine is connected with horizontal bubble. The utility model discloses through the lifting of threaded rod and fixed plate, can flexibly adjust the height of support foot, and further adjusts the position of rolling bottle machine. The application of horizontal bubble is combined, ensures the accurate horizontal nature of adjustment process, and continuously keeps the stable placement of rolling bottle machine, thereby guarantees the stability of cell culture rolling bottle processing in rolling bottle machine.

This invention relates to a stem cell culture method using a roller bottle for improving the yield and quality of separation and purification of extracellular vesicles, and to a method for separating stem cell-derived extracellular vesicles. When exosomes or extracellular vesicles are separated from a culture medium obtained by culturing stem cells using the roller bottle method, the yield is greatly increased, and high-quality extracellular vesicles with high CD9 and CD81 expression can be obtained. As a result, stem cells can be cultured in large quantities using the stem cell culture method using the roller bottle of the present invention, and exosomes and extracellular vesicles can be separated and purified with high yield.

A rotating tissue culture insert for positioning inside a rotatable roller bottle partially filled with a liquid for the cultivation of cells includes a scaffold provided for the cultivation of cells, an axle body, and at least two protrusions extending in radial direction from the axle body. The protrusions define wheels of the rotating tissue culture insert with a runway that is in contact with the surface of a roller bottle when the roller bottle is in a lying position.