The invention relates to a method and a system for automatically generating an urban road traffic guidance strategy. According to the method and the system, by applying the intelligent traffic theory, the spatial autocorrelation theory, the fuzzy mathematic theory, an statistical method and the computer technology, real-time traffic flow data and historical data are researched and processed, and therefore, under the condition that a traffic incident occurs in a road traffic network, the traffic guidance strategy which can be released in time through VMS (variable message signs) on a road is automatically generated. According to the method and the system, by taking historical artificial guidance information and the real-time traffic flow data as input data, on the basis that historical guidance empirical laws are analyzed and real-time traffic flow features are excavated, a final guidance release strategy is determined by applying a traffic state spatial inequality analysis method provided by the invention. A proposal and strategy scheme can be provided for the quick release of the guidance information of an urban traffic management department when certain traffic incidents occur, such as road accidents, congestion, severe weather, management and control, and the like.