The invention discloses a rotary type unilateral opening adjustable sealing structure. The sealing structure comprises a box body, a box cover, a connecting pipe, a seal ring, a rotating device and alocking device, wherein the rotating device comprises a rotating seat and a rotating shaft, the connecting pipe is rotationally connected with the box cover through the rotating shaft, the locking device is arranged on the side opposite to the rotating device, the locking device comprises a clamping hook assembly and a lock catch assembly, the clamping hook assembly comprises a dovetail groove, fixing bolt holes, adjusting fixing bolt holes and a clamping hook, the fixing bolt holes are formed in the surface of the clamping hook assembly, the adjusting fixing bolt holes are arranged on the twosides of the clamping hook assembly, the clamping hook is arranged at the protruding part of the clamping hook assembly, moreover, an arc-shaped groove is formed in the tail end of the clamping hook,the lock catch assembly comprises a lock catch base and a lock catch, the lock catch base is fixed on the surface of the box cover, the buckling part of the lock catch is connected with the clampinghook in a buckling mode, the two sides, inside the rotating device, of the rotating seat are also provided with adjusting fixing bolt holes, and the surface of a pressing plate of the connecting pipeis also provided with adjusting bolt holes matched with the adjusting fixing bolt holes.