The invention relates to a mixed heterodyne multi-frequency anti-aliasing laser ranging device and a mixed heterodyne multi-frequency anti-aliasing laser ranging method, belonging to a phase laser ranging technology. The ranging device comprises a measuring ruler generating unit, a laser frequency shifting unit, an anti-aliasing measuring light path and a phase measuring unit. The ranging method comprises the following steps: step one, starting a frequency standard laser, an offset frequency locking semiconductor laser and a He-Ne laser; step two, taking a beam as a reference laser beam, and the other beam as measuring laser; step three, taking c/|v2-v3| as accurate measuring ruler length; step four, taking c/|v1-v2| as rough measuring ruler length; and step 5, moving a measuring retroreflector to a target end to respectively obtain phase difference phi 1 and phi 2 of the accurate measuring ruler and the rough measuring ruler, and finally obtaining a measured distance value through a formula. The mixed heterodyne multi-frequency anti-aliasing laser ranging device and the method provided by the invention solve the problems that ultralong wavelength and ultrashort wavelength cannot be generated simultaneously, the laser measuring ruler cannot realize direct traceability, and nonlinear periodical error and frequency aliasing are caused, and has the characteristics of high measurement efficiency, high precision, and strong stability and real-time property.