The invention discloses a softening device applicable to processing of traditional Chinese medicine decoction pieces. The softening device comprises a softening chamber, a seal door, a water delivery pump, a water delivery pipe, water spray pipes and bearing trays, and is characterized in that the softening chamber is formed in a bracket, the seal door is connected with the softening chamber through a hinge, the water delivery pump is arranged on the softening chamber, the water delivery pipe is arranged in the softening chamber and connected with the water delivery pump, the water spray pipes are arranged on the water delivery pipe, atomizing nozzles are arranged on the water spray pipes, and the bearing trays are arranged on fixing rods. The water spray pipes are arranged on the water delivery pipe on the water delivery pump, and the atomizing nozzles are arranged on the water spray pipes, so that water can be atomized by the atomizing nozzles and sprayed to surfaces of the traditional Chinese medicine decoction pieces in the bearing trays, water is provided for softening the traditional Chinese medicine decoction pieces, water consumption can be reduced, softening uniformity of the traditional Chinese medicine decoction pieces can be improved, and softening quality of the traditional Chinese medicine decoction pieces can be enhanced.