The invention discloses a treatment and safe discharge system for hospital medical waste gas. The system comprises a dust remover, an airtight heater, a reactor, a filter, a main induced draft fan and a circulating fan, which are connected in sequence, wherein the dust remover, the airtight heater, the reactor, the filter and the gas inlet and outlet port of the main induced draft fan are connected in sequence; the inlet of the circulating fan is connected with the filter, and the outlet of the circulating fan is connected with the reactor; a temperature sensor, a pressure sensor and a flow sensor are arranged in the system and measurement signals are processed through a measurement module; according to the measurement signals, an automatic control module adjusts the working state of the dust remover, the airtight heater, the reactor and fan equipment so as to meet the requirements of current medical waste gas treatment. The system has a wide treatment range of medical waste gas and a good treatment effect and has the characteristics of high convenience in mounting and maintenance and relatively lower investment.