The invention discloses an automatic wire take-up device of a medical device. The automatic wire take-up device comprises a wire take-up box, wherein the wire take-up box is of a cavity structure, oneside of the wire take-up box is provided with a fixing plate, the upper portion and the lower portion of the side, close to the wire take-up box, of the fixing plate are both provided with a plurality of fixing screws, the middle of the side, away from the fixing plate, of the wire take-up box is provided with a ceramic wire ring, the inner side of the wire take-up box is provided with a wire protecting sleeve, the inner side of the wire protecting sleeve is provided with an installing base, a wire reel and a supporting sleeve, the installing base and the supporting sleeve are located on twosides of the wire reel, the installing base is fixed to the inner wall of the wire take-up box, the side, close to the wire reel, of the installing base is provided with a fixing rod, the side, closeto the installing base, of the fixing rod is sleeved with a sleeve, the inner side of the wire reel is provided with a through hole, the inner side of the through hole is provided with a bearing I, and the inner side of the bearing I is provided with an inner core. The automatic wire take-up device has the advantages of facilitating wire storage and carding and creating of an orderly, light and spacious treatment environment.