44results about How to "To achieve the purpose of sustained and controlled release" patented technology

The invention discloses a sustained/controlled release microsphere of a chitosan coated stilbene compound using a biological extract Genipin as a cross-linking agent and a preparation method thereof. In the microsphere, a cross-linked condensation compound layer of the chitosan and the Genipin serves as a capsule shell and is used for coating a medicament 3,5-dihydroxyl-4-isopropyl stilbene, resveratrol, pterostilbene, oxidized resveratrol or piceatannol; the medicament stability of the product is improved; the sustained/controlled release of the medicament is realized; and the released Genipin after in vivo metabolism of the capsule shell has the characteristics of biocompatibility, no cytotoxicity and the like. The invention is applicable to the sustained/controlled release microspheresof Genipin cross-linked chitosan coated 3,5-dihydroxyl-4-isopropyl stilbene, resveratrol, pterostilbene, oxidized resveratrol, piceatannol and other stilbene compounds and a preparation method thereof. The preparation method is low in requirements on the control condition and easy to operate. In the microspheres, the quality is uniform; the grain size is 0.1 to 100 mu m; the surface of the microsphere has a multiporous structure; and the entrapment rate of the capsule shell to the medicament is 30 to 90 percent.

The invention discloses a production method of a spraying sulfoacid resin type sustained and controlled release fertilizer, comprising the following steps: 1, putting a granular fertilizer in a granulation device for preheating; 2, putting urea in a fusion device for fusing, when urea is completely fused, adding sulphur powder, polyvinyl alcohol and cinnamic acid ester in the fused urea, uniformly stirring, then filtering to obtain a fused urea resin sulphur liquid with uniform quality, allowing the preheated granular fertilizer to form a material curtain in the granulation device, and uniformly spraying the fused urea resin sulphur liquid on the surfaces of the fertilizer particles; 3, carrying out cooling on the sprayed fertilizer in a cooling device; and 4, adding a conditioner in the particle cooling device. The prepared fertilizer disclosed herein can achieve the sustained and controlled-release purpose of the fertilizer, and can thoroughly solve the problem of secondary pollution to soil from the traditional coated sustained and controlled-release fertilizers. In addition, the production method has the advantages of simple process and low production cost, and can be used forforming large scale production.

The invention discloses high-specific-surface-area N-doped surface-modified silkworm excrement-based microporous carbon material and a preparation method and application thereof; silkworm excrement and water are mixed and swelled and then lyophilized, the lyophilized silkworm excrement is then prepared into carbonized silkworm excrement under a protective gas, the carbonized silkworm excrement is then mixed with KOH, mixture is subjected to activation and pore-enlarging reaction in the protective gas and is then washed, centrifuged and dried to obtain the high-specific-surface-area silkworm excrement-based microporous carbon material, and N2 atmosphere is then introduced into a plasma reactor to prepare the high-specific-surface-area N-doped surface-modified silkworm excrement-based microporous carbon material; the material is applicable to pesticide release control; silkworm excrement is carbonized and activated at high temperature in the protective gas, the material is subjected to N-doped surface modification by means of plasma modification, and the obtained carbon material has high specific surface area and controllable N-containing polar groups and has high adsorbing capacity and good release control effect for pesticides.

The invention discloses a high-specific-surface-area basic oxide surface-modified silkworm faeces-based microporous carbon material and a preparation method and application thereof. The preparation method comprises the following steps: mixing and swelling silkworm faeces and water to obtain a mixture, performing freeze drying on the mixture, and preparing carbonized silkworm faeces from the freeze-dried silkworm faeces under protection gas; mixing the carbonized silkworm faeces with KOH, performing activating and reaming reaction in the protection gas, and then performing cleaning, centrifugation and drying to obtain a high-specific-surface-area silkworm faeces-based microporous carbon material; stirring and mixing a metal salt solution with the material, performing centrifugation and drying, and feeding oxygen to prepare a plasma modified basic oxide surface-modified silkworm faeces-based microporous carbon material. The material is applied to the aspect of controlled release of pesticides. According to the preparation method, the silkworm faeces can be carbonized and activated at high temperature under the condition of the protection gas, and basic oxide surface modification is carried out by a soaking method and a plasma modification mode, so that the obtained carbon material is higher in specific surface area and alkaline adsorption site, and has higher adsorption capacity for the pesticides and a better controlled release effect of the pesticides.

The invention discloses an N-doping surface modification silkworm excrement-based multi-stage hole carbon material and a preparation method and application thereof. Firstly, silkworm excrement and ZnCl2 solution are subjected to mixed swelling; then, freeze drying is performed; the silkworm excrement subjected to freeze drying is subjected to activation hole expansion reaction in protection gas; next, cleaning, centrifugation and drying are performed to obtain a silkworm excrement-based microporous carbon material; next, N2 gas is introduced for preparing the N-doping surface modification silkworm excrement-based multi-stage hole carbon material in a plasma reactor; the material can be applied to the aspect of pesticide slow and controlled release. The protection gas condition is used for performing activation treatment at high temperature; then, by using a plasma modification mode, the material is subjected to N-doping surface modification, the obtained carbon material has high specific surface area and controllable N polar groups; high adsorption volume and good slow and controlled release effects are achieved.

The invention discloses a slow-release traditional Chinese medicine package for coarse salt hot compress and a preparation method thereof. The slow-release traditional Chinese medicine package comprises folium artemisiae argyi, flowers carthami, angelica sinensis, lycopodium clavatum, rhizoma acori graminei, mastic, dandelion and beta cyclodextrin. In the components of the slow-release traditionalChinese medicine package, the folium artemisiae argyi and the lycopodium clavatum have therapeutic effects of eliminating cold to stop pain, relaxing tendons and activating collaterals; the flowers carthami, the angelica sinensis and the rhizoma acori graminei have the effects of activating blood, removing stasis, nourishing the blood and promoting blood circulation; the mastic and the dandelioncan achieve obvious therapeutic effects of clearing away heat and toxic materials, diminishing inflammation and relieving pain; the beta cyclodextrin can form an inclusion complex together with guestmolecules matched with the size of a cavity, so as to improve the stability of the guest modules; and when the beta cyclodextrin and the traditional Chinese medicines are mixed, effective components in the traditional Chinese medicines can be adsorbed, so that in a heating process, the slow release cycle of the medicines is greatly prolonged to fulfill the aim of slow and controlled release of themedicines to achieve a long-acting medicine effect, and the number of times of use of the slow-release traditional Chinese medicine package is effectively increased.

The invention discloses a high-specific-area O-doped surface-modified silkworm-excrement-based microporous carbon material as well as a preparation method and an application thereof. Firstly, silkworm excrement and water are mixed, swelled and freeze-dried, and carbonized silkworm excrement is prepared from the freeze-dried silkworm excrement in the protective gas; the carbonized silkworm excrement and KOH are mixed and subjected to an activation pore enlargement reaction in the protective gas, a high-specific-area silkworm-excrement-based microporous carbon material is obtained after washing, centrifugation and drying, and the high-specific-area O-doped surface-modified silkworm-excrement-based microporous carbon material is prepared in a plasma reactor in the oxygen atmosphere and can be applied to sustained or controlled release of pesticides. The silkworm excrement is carbonized and activated under the protective gas condition at the high temperature, O-doped surface modification is performed on the material in the plasma modification manner, and the obtained carbon material has the higher specific surface area and controllable O-containing polar groups and can have the higher adsorption capacity and the better sustained or controlled release effect on the pesticides.

The invention discloses a dopamine-silkworm excrement composite carbon material high in specific surface area and a preparation method and application thereof. The preparation method includes: preparing raw silkworm excrement into carbonized silkworm excrement under protective gas; mixing dopamine hydrochloride powder with the carbonized silkworm excrement, adding a ZnCl2 solution, placing into a high-speed mechanical ball mill to perform oscillation activation grafting reaction to obtain dopamine/ZnCl2/silkworm excrement slurry, and drying the slurry to obtain a crude composite material; performing activation pore-expanding reaction on the crude composite material under protective gas, cleaning, centrifuging, and drying to obtain the dopamine-silkworm excrement composite carbon material high in specific surface area. The preparation method has the advantages that high-speed mechanical oscillation is used to perform grafting compositing on the dopamine hydrochloride and the silkworm excrement and mix the composited dopamine hydrochloride and silkworm excrement with activating agent ZnCl2 to perform primary activation, the grafting composting reaction speed of the two materials are increased greatly, the dispersity of the activating agent on the surface of the silkworm excrement composite material is increased greatly, and the obtained composite carbon material is high in specific surface area, contains N polar groups, and is high in pesticide absorption capacity and good in sustained-release effect.