The invention belongs to leather process technology, in particular a method for producing chamois leather using epoxidized oil, comprising the following steps: putting the pretanned pelt or fur into the normal temperature controlled rotary drum, adding alkaline solution to adjust pH value into alkaline, draining the alkaline solution, and adding catalyst or accelerant and epoxidized oil into the rotary drum, keeping the temperature at a certain temperature for several times, after reacting, recycling the remaining oil, then washing using degreasant and/or alkali, then adjusting pH value, aluminum tanning, aldehyde tanning or other tanning, and then drying, dampening and milling, finally gaining the chamois leather. The invention enables epoxidized oil to directly react with collagen and fix oil on the hide fiber, so that the shortcoming that traditional oil tanning takes oil as raw material, instead of reactant is overcome, and oil oxidizing process of traditional chamois leather is omitted. The chamois leather produced by the method has advantages of high intensity, good flexibility, strong hygroscopicity and water-wash resistance, applicable for the leather for cleaning, filtering and washing clothes.