The invention discloses a systematic solution for voltage quality evaluation and optimization of low-voltage transformer area distribution networks. The systematic solution comprises the following steps: collecting topological structures, circuit parameters, phase sequence of tail end users, and load curve characters of the distribution networks in all low-voltage transformer areas to establish a low-voltage transformer area mathematical model; calculating average power or instantaneous power of users according to user consumption data in a marketing system of a power supply enterprise, and computing an active power, a line loss rate and each node voltage value of each section of a line through a forward-backward sweep distribution system power flow calculation method; performing optimal design and simulation analysis on the low-voltage transformer areas through modes of transferring load, newly increasing lines, changing lines and adjusting phase sequence to realize the optimal line loss rate and investment costs comprehensively. According to the solution, with a developed software platform, workload of line patrol and modeling in the low-voltage transformer areas can be greatly reduced, real-time data updating of the low-voltage transformer areas can be realized by basic-level power supply stations (offices) through combining with corresponding management measures, and the operation and maintenance level of the low voltage distribution networks can be improved.