38 results about "Oncology drugs" patented technology

The invention relates to the technical field of medical devices, and discloses a medical oncology drug delivery device, comprising a first drug delivery box and a second drug delivery box. A knob is arranged on the left side of the medicine feeding tube, the knob is sleeved on the outer wall of the left end of the rotating shaft, the right side of the knob is in contact with the left side of the sealing ring, and the right side of the sealing ring is in contact with the left side of the medicine feeding tube. contact, the sealing ring is sleeved on the outer wall of the rotating shaft, the right end of the rotating shaft runs through the left side of the medicine inlet tube and the left side of the closing plate in turn and extends to the right side of the medicine inlet tube, and the upper part of the first medicine box is provided There is a first drive motor. By pulling the two pull rings relative to each other, the two blocks can be moved relative to each other, and the two connecting blocks can also be moved relative to each other until the two blocks are disengaged from the bayonet, and then move the stirring blade to the left, and finally the disassembly can be completed, which is convenient Clean the stirring blades.

Dry powder formulations for inhalation and their use in the treatment diseases and conditions. The formulation contains a uniform blend of a first spray-dried powder and a second spray-dried powder. The first spray-dried powder contains spray-dried particles of a therapeutically active ingredient dispersed in a pharmaceutically acceptably hydrophobic excipient. The second spray-dried powder contains spray-dried particles formed from a pharmaceutically acceptable hydrophobic excipient but are substantially free of any therapeutically active ingredient. The active ingredient in the first spray-dried powder is loaded sufficiently high to compensate for the second spray-dried powder being substantially free of any active ingredient. A process for preparing such formulations is also described.

The invention belongs to the field of biotechnology, and provides a back-shaped LNA probe for point mutation detection and applications thereof. The probe is an oligonucleotide with a length of 25 to 30 bp; the 5' end of the oligonucleotide is Label the luminescent group, label the quencher group at the 3' end, and make an LNA label on a base in the middle. The invention is suitable for single-base mutation detection, with simple and effective design, and is suitable for mainstream detection platforms on the market; the specificity of mutation detection is improved, the detection result of drug gene polymorphism is more accurate, and the effect of drug treatment is improved; the sensitivity of mutation detection is improved, Provide solutions for companion diagnosis and efficacy testing of tumor drugs.

The invention discloses the application of Desogestrel in the preparation of anti-colon cancer / ER-negative Ah receptor-positive breast cancer products. The invention provides the application of Desogestrel in the preparation of products for treating colon cancer and / or breast cancer. Experiments of the present invention prove that the present invention repositions the drug Desogestrel, which has been approved by FDA and CFDA, and screens drugs whose indications are not anti-tumor according to different cell lines (tissue types) and mutation sites of the tumor, and finds that The new use of Desogestrel against colon cancer realizes the new use of old drugs.

The invention discloses a drug delivery device for medical oncology, which comprises a needle body, the inner side wall of the needle body is fixedly connected with a syringe, the inner side wall of the syringe is sealed and slidably connected with a piston, and the top of the piston is fixedly connected with a Push rod, the outer wall of the needle body is fixedly connected with a positioning block, the outer wall of the needle body is fixedly connected with a liquid medicine tank, the bottom of the liquid medicine tank is fixedly connected with a positioning seat, and the inner side of the liquid medicine tank is fixedly connected with a positioning block. The wall is sealed and slidably connected with a slide plate, and the top of the slide plate is connected with a dosing tube through a sealed slide connection. The present invention realizes the repeated absorption of the liquid medicine in the syringe through the pressure difference, which improves the injection efficiency of the diseased part of the patient and greatly improves the Reduce the pain of the patient, save the time of the medical staff, better ensure the stability of the connector by fixing and sealing the joint, and prevent the loss of the connector and the extravasation of the drug solution from causing damage to the patient's skin. damage, protecting the safety of the patient and improving the stability of the device.

The present invention relates to a compound seven (6-(isoquinoline-3-amido)-6-deoxy)-β-cyclodextrin with anti-tumor activity and a preparation method thereof. Application in tumor medicine. The compound of the present invention has cytotoxicity in vitro and anti-tumor activity in vivo, and relates to the inhibitory effect on the cytotoxic activity of five tumor cell proliferations of A549, HCT-8, HeLa, SW480, and S180. The compound of the present invention has good anti-tumor activity and can It is used in the preparation of antitumor drugs, and the invention belongs to the field of biomedicine.