195 results about "Optical noise" patented technology

Apparatus, systems and methods for use in analyzing discrete reactions at ultra high multiplex with reduced optical noise, and increased system flexibility. Apparatus include substrates having integrated optical components that increase multiplex capability by one or more of increasing density of reaction regions, improving transmission of light to or collection of light from discrete reactions regions. Integrated optical components include reflective optical elements which re-direct illumination light and light emitted from the discrete regions to more efficiently collect emitted light. Particularly preferred applications include single molecule reaction analysis, such as polymerase mediated template dependent nucleic acid synthesis and sequence determination.

An optical touchpad that may be able to provide accurate, reliable information about the position of an object in three-dimensions. The optical touchpad may enable a determination as to whether the object is engaged with the touchpad or hovering just above the touchpad. When the object is in contact with the optical touchpad, the optical touchpad may enable a determination of the force applied by the object to the optical touchpad. The optical touchpad may enable a determination of an object type of the object. These and other determinations of information related to the object may enhance the control provided by the touchpad system to the user as an electronic interface. The operation of the optical touchpad may further enable an enhanced frame rate, reduced optical noise in the optical signal(s) guided to the one or more sensors, augment the ruggedness of the optical touchpad, an enhanced form factor (e.g., thinner), and / or provide other advantages.

The present invention relates, in general, to a fluorescence microscope and method of observing samples using the microscope and, more particularly, to a fluorescence microscope and method of observing samples using the microscope, which can reduce optical noise and obtain images with higher sensitivity, thus obtaining precise information about the density, quantity, location, etc. of a fluorophore, and which can simultaneously process separate images even when a plurality of fluorophores having different excitation and fluorescent wavelength ranges is distributed, thus easily obtaining information about the fluorophores. The fluorescence microscope of the present invention includes an objective lens, and first and third medium units. The first medium unit has a refractive index of n1 to accommodate one or more micro-objects including fluorophores and provide a path of excitation light to excite the fluorophores. The third medium unit has a refractive index of n3, and is placed between the first medium unit and the objective lens to totally reflect the excitation light incident through the first medium unit at an interface of the third medium unit coming into contact with the first medium unit. The refractive indices of the third and first medium units satisfy a relationship of n1>n3.

Systems and method for detecting optical signals, and for discriminating optical signals emitted by an emission moiety that is excited by an associated excitation signal from background signals and other optical noise, employing digital techniques for determining the portion of a detected optical signal having a modulation frequency corresponding to a modulation of the associated excitation signal.

A laser diode structure for generating a collimated or divergent laser beam, preferably for application in gas detection, with a laser diode arranged in a closed housing, with the housing comprising a housing bottom, an exit window, electrical connections, a temperature control device for the laser diode, and an optical element for influencing the laser beam. The temperature control device carrying the laser diode is arranged on the housing bottom and the optical element is positioned at a distance from the laser diode. The invention proposes an electrically controllable power device for the cyclic alteration of the position and / or alignment of the optical element in relation to the laser diode so that the optical path length for the laser beam in the housing changes periodically. The oscillating motion of the optical element has the effect of time-averaging the etalon and / or self-mixing effects caused by the back-reflections of the laser beam in the housing, thereby reducing the optical noise of the laser diode structure.

An optical transmission system with automatic startup functions to optimize the power level of optical signals entering each optical amplifier and operate those amplifiers in appropriate mode. In the process of starting up an optical transmission system, upstream and downstream optical transmission devices set up themselves under the coordination of their internal controllers. The downstream device controller adjusts its local variable optical attenuator by utilizing optical noise emission from a post-amplifier in the upstream optical transmission device, and it selects and sets a preamplifier unit to work in appropriate operating mode. The upstream device controller, on the other hand, selects and sets operating mode of its local post-amplifier unit. During this process, the upstream and downstream device controllers exchange messages over supervisory control channels to achieve the purpose.