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41 results about "Renal stone" patented technology

Medical device and methods of use

The present disclosure is directed to a medical device. Systems and methods are provided for utilizing a laser to break a kidney stones into smaller fragments and / or dust, and removing particles, stone fragments and / or stone dust from a patient. The medical device may include a delivery device including a tube, and an elongate member having a distal end, a proximal end, and a lumen extending between the proximal end and the distal end, wherein the elongate member is configured to move axially relative to the tube and apply suction through the distal end.
Owner:BOSTON SCI SCIMED INC

Puncture oriented adherent observation type puncture endoscope for percutaneous renal stone-extraction operation

ActiveCN101390771AReduce potential riskRealize the purpose of real-time observationSuture equipmentsInternal osteosythesisCamera lensFailure rate
The invention relates to a puncture endoscope used for attached observation for puncturing and orientation in percutaneous nephrolithotomy, solving the technical problems of poor puncture accuracy, big amount of bleeding, high operation failure rate and poor safety of the existing appliances used in percutaneous nephrolithotomy. The puncture endoscope comprises a main endoscope body, an image transferring unit, a lighting unit, an ocular unit and a puncture body. The puncture body is composed of a puncture needle and an indwelling catheter. The ocular unit is composed of an ocular cover, an ocular lens and an ocular glass. The image transferring unit is composed of a multi-filament image transferring rod arranged inside a hollow outer tube of the puncture needle. The lighting unit is composed of a light beam collet which can be connected with the main endoscope body, a light beam interface which is arranged on the light beam collet and can be connected with an external light source, a light cone arranged inside the light beam interface, and a light transferring component which can transfer the external light source which passes through the light cone to the imaging surface of the multi-filament image transferring rod. The puncture body is fixedly arranged at the front end of the main endoscope body. The puncture endoscope has the advantages of good visibility during operations, high puncture accuracy, less bleeding, high operation success ratio and high safety and is unnecessary to be charged with water.
Owner:FEMTO TECH XIAN

Method and apparatus for providing medical treatment using visualization components of audio spectrum signals

The present disclosure relates to medical imaging and treatment devices and methods. A system is provided that provides location and treatment of kidney stones or other entities through the use of visual representation of audio signals.
Owner:MASTER KEY LLC

Puncture body disposable adherent observation type puncture endoscope for percutaneous renal stone-extraction operation

InactiveCN101390770AReduce potential riskRealize the purpose of real-time observationSuture equipmentsInternal osteosythesisFailure rateEyepiece
The invention relates to a disposable puncture endoscope used for attached observation of a puncture body in percutaneous nephrolithotomy, solving the clinical restrictions of poor puncture accuracy, big amount of bleeding, high operation failure rate and poor safety of the existing appliances used in percutaneous nephrolithotomy. The puncture endoscope comprises an ocular unit, an image transferring unit, a main endoscope body, a lighting unit and a puncture body. The puncture body is composed of a disposable puncture needle and an indwelling catheter. The disposable puncture needle comprises a hollow outer tube and a plastic needle body. The ocular unit is composed of an ocular cover, and an ocular glass and an ocular lens which are arranged inside the ocular cover. The image transferring unit is composed of a multi-filament image transferring rod arranged inside the hollow outer tube of the puncture needle. The front end of the main endoscope body is connected with the plastic needle body of the puncture needle and the back end of the main endoscope body is connected with the ocular cover of the ocular unit. The lighting unit is composed of a built-in lighting component and a detachable lighting component. The puncture endoscope has the advantages that the puncture endoscope is good in visibility during operations, high in puncture accuracy, less in bleeding, high in operation success ratio and high in safety and is unnecessary to be charged with water.
Owner:FEMTO TECH XIAN

Devices and methods for guiding a surgical instrument

Devices for guiding an instrument into a body of a patient, at a targeted point of entry and along an insertion path at a targeted insertion angle, are described herein, such as a guide for an accessneedle in a PCNL procedure for accessing the kidney to remove kidney stones, the devices comprising a base component, a guide assembly, and optionally an insertion mechanism. The base component is aligned in use with the point of entry and the guide assembly cooperates with the base component to allow for the instrument to be aligned and fixed at any circumferential angle around an axis perpendicular to the point of entry and at any vertical angle ranging from 0 to 45 degrees away from the axis in a direction toward the body. The optional mechanism allows for mechanical insertion once the instrument is aligned and fixed. Devices and methods disclosed herein allow a medical professional to accurately and stably guide an instrument at a targeted point and angle and to a desired depth, whileminimizing the exposure to radiation in the surgical field that is used to image the insertion path.
Owner:BOSTON SCI SCIMED INC

Medicine for treating kidney calculi

ActiveCN102441142AIncrease gasification functionDissolve smooth muscle spasmsUrinary disorderPlant ingredientsSide effectGymnema yunnanense
A medicine for treating kidney calculi in the invention contains the following raw materials of: by weight, 6-8 parts of Rhamnella gilgitica Mansf. Melch., 8-10 parts of changuienia amoena chien, 6-8 parts of Gymnema yunnanense Tsiang, 3-5 parts of evening primrose, 8-10 parts of common adenostema herb, 8-10 parts of Lysimachia congestiflora Hemsl, 2-4 parts of dry maidenhair fern herb, 3-5 partsof Chinese cassia tree, 6-8 parts of bighead atractylodes rhizome, 6-8 parts of Poria cocos, 3-5 parts of gentrin knotweed, 2-4 parts of desmodium, 4-6 parts of Lygodium japonicum, 2-4 parts of SemenAbutili, 3-5 parts of plantago, 4-6 parts of radix bupleuri, 6-8 parts of oriental waterplantain rhizome, 3-5 parts of rheum officinale, 4-6 parts of white peony root, 1-3 parts of Artemisia capillaries and 1-3 parts of curcuma tuber. The medicine provided by the invention has effects of invigorating kidney qi, increasing functioning of bladder, keeping urinary function normal, dissolving stone, expelling stone, reducing renal colic and ureteral smooth muscle spasm, promoting qi circulation and relieving pain, clearing heat and draining dampness, and draining calculus. The effect of rushing, dissolving and draining calculus can be reached. In addition, the medicine provided by the invention has advantages of good curative effect, little side-effect and low cost.
Owner:如东文园投资开发有限公司

Assessing risk for kidney stones using parathyroid hormone agonist and antagonist

The present invention relates to identifying the risk of a subject developing renal stones utilizing an assessment of PTH agonist, antagonist and / or total PTH levels, optionally together with an assessment of serum and / or urine calcium levels and / or other analytes. The present description further relates to monitoring and guiding treatment for renal stones and kits useful therefore.
Owner:SCANTIBODIES LAB

Traditional Chinese medicine compound and formulation for removing renal stone

The present invention pertains to the technical field of medicine in particular relates to Chinese traditional medicine Kidney Tea removal of urinary calculus complex prescription and preparation used for preventing and curing urinary calculus, removing urinary calculus, promoting urination and anti-inflammatory. The Chinese traditional medicine complex prescription mainly comprises kidney tea and herba lysimachiae. In mixture ratios of components, the prescription comprises 1 to 10 times of kidney tea, and 1 to 10 times of herba lysimachiae and comprises 10 to 180g of kidney tea and 10 to 180g of herba lysimachiae in weight ratio. Various convenient medicament forms are made according to conventional extraction and preparation technology of the Chinese traditional medicine kidney tea urinary calculus removal complex prescription. Experiments of the Chinese traditional medicine kidney tea urinary calculus removal complex on animals indicate that the medicine has the advantages of reducing fever, eliminating dampness, removing urinary calculus, promoting urination and resisting inflammation. The medicine is used for preventing and curing the urinary calculus. The urinary calculus can be effectively discharged from body within a relatively short time after the medicine is taken by patients. Raw materials for the Chinese traditional medicine contained in the Chinese traditional medicine kidney tea urinary calculus removal complex prescription and the preparation are broad in source, scientific in processing, scientific in operation, high in effective ingredient of the finished product and convenient in use.
Owner:ZHEJIANG ACAD OF MEDICAL SCI

Medicinal composition for treating kidney calculi

The invention provides a medicinal composition for treating kidney calculi. The medicinal composition is prepared from the following traditional Chinese medicinal raw materials in parts by weight: 3-5 parts of selfheal, 20-40 parts of christina loosestrife herb, 60-70 parts of endothelium corneum gigeriae galli, 10-15 parts of rhizoma alismatis, 10-20 parts of rheum officinale, 6-8 parts of lygodium japonicum, 6-8 parts of liquorice, 5-6 parts of red peony root, 3-6 parts of chingma abutilon seed, 1-3 parts of rush, 6-8 parts of polygonum aviculare, 20-25 parts of dandelion, 8-12 parts of pyrrosia lingua, 10-15 parts of corn stigma, and 5-10 parts of radix curcumae. The medicinal composition can be used for treating kidney calculi, and has a good curate effect on other lithangiuria. Due to the traditional Chinese medicinal herbs, the medicinal composition has a small side effect, and can be easily accepted by massive patients.
Owner:钱家美

Traditional Chinese medicine formula and capsule for dissolving kidney stone

InactiveCN102755456BLow priceSuitable for disease prevention and treatmentInorganic boron active ingredientsUrinary disorderMedicinal herbsHerb medicine
A traditional Chinese medicine formula for dissolving a kidney stone belongs to the field of traditional Chinese formulas and capsule formulations, and comprises the following components by weight ratio: notoginseng, sambucus javanica, plantain, glechoma longituba, medical borax, calcined alum and natrii sulfas exsiccatus. A preparation method comprises the steps as follows: the first four medicinal herbs (notoginseng, sambucus javanica, plantain and glechoma longituba) are immediately cleaned after being picked, dried in the sun, crushed, and sealed respectively for mold prevention and insect prevention; and when in use, the four herbs are warmed over medium-high heat for 10 minutes respectively and are mixed with the other three herbs (medical borax, calcined alum and natrii sulfas exsiccatus) according to a proportion, and then all the herbs are crushed, disinfected, sterilized, and then filled in capsules NO.0, with each capsule weighing 0.65 g.
Owner:肖友旭

Traditional Chinese medicine formula and capsule for dissolving kidney stone

InactiveCN102755456ALow priceSuitable for disease prevention and treatmentInorganic boron active ingredientsUrinary disorderMedicinal herbsHerb medicine
A traditional Chinese medicine formula for dissolving a kidney stone belongs to the field of traditional Chinese formulas and capsule formulations, and comprises the following components by weight ratio: notoginseng, sambucus javanica, plantain, glechoma longituba, medical borax, calcined alum and natrii sulfas exsiccatus. A preparation method comprises the steps as follows: the first four medicinal herbs (notoginseng, sambucus javanica, plantain and glechoma longituba) are immediately cleaned after being picked, dried in the sun, crushed, and sealed respectively for mold prevention and insect prevention; and when in use, the four herbs are warmed over medium-high heat for 10 minutes respectively and are mixed with the other three herbs (medical borax, calcined alum and natrii sulfas exsiccatus) according to a proportion, and then all the herbs are crushed, disinfected, sterilized, and then filled in capsules NO.0, with each capsule weighing 0.65 g.
Owner:肖友旭

Upper urinary tract integrated support drainage catheter

The invention discloses an upper urinary tract integrated support drainage catheter and relates to medical instruments used for urinary tract drainage. The upper urinary tract integrated support drainage catheter comprises a fistulization tube and a connector. The fistulization tube comprises a short thin tube part in a pigtail coil shape, and a long thick tube part for drainage, wherein the long thick tube part is connected with the thin tube part. The joint of the thin tube part and the thick tube part is conical. The tail end can be bent, the long and thin end can be arranged in a ureter whole section, and the tail end is located in the urinary bladder. When the fistulization tube is pulled out, after the thick part of the fistulization tube leaves skin, the tail end of the long and thin part is still located in a collecting system. The upper urinary tract integrated support drainage catheter can drain an upper urinary tract, and the thin part is equivalent to a double J tube; during channel bleeding, bleeding stopping can be achieved through inflation air bags and traction compression; a drainage catheter can be slowly pulled out after a patient suffering from percutaneous renal stone breaking is in anesthetic awareness; in addition, the drainage tube can be tightly connected with the connector through a stepped structure, and no disengagement is likely to happen.
Owner:徐亚文

Traditional Chinese medicine for treating kidney stone and preparation method thereof

The invention relates to a Chinese medicament for treating kidney stone and a preparation method thereof, belonging to the technical field of traditional Chinese medicines and preparation methods thereof. The traditional Chinese medicine for treating kidney stone is characterized by comprising the following medical components in portion by weight: 10-15 portions of pyrrosia lingua, 10-15 portionsof malva seed, 10-15 portions of herba dianthi, 5-10 portions of peony, 10-20 portions of field thistle, 10-15 portions of dried rhizome of rehmannia, 1-3 nodus nelumbinis rhizomatis, 5-10 portions ofcorn silk, 10-20 portions of walnut-meat, 10-15 portions of clematis chinensis, 10-20 portions of chloranthus glaber and 10-15 portions of sunflower stem pith. The traditional Chinese medicine for treating kidney stone and the preparation method thereof have low cost, good curative effect, quick response, no relapse or toxic and side effects, and the traditional Chinese medicine is suitable for various groups to use.
Owner:宋广艳

Traditional Chinese medicine formula composition capable of removing kidney stone and preparation method of composition

The invention relates to traditional Chinese medicine formula composition capable of removing kidney stone. The composition comprises raw traditional Chinese medicine materials as follows: 15-20 g of chicken's gizzard-membrane, 10-15 g of lygodium japonicum, 8-10 g of rhizoma alismatis, 10-15 g of seaweeds, 8-10 g of rheum officinale, 5-8 g of hawthorns and 5-10 g of Chinese cinquefoil herbs. Through the compatibility of various raw traditional Chinese medicine materials, particularly certain raw natural traditional Chinese medicine materials, active ingredients of the medicine are well dissolved in a decoction; and the composition is taken orally, so that the body can better absorb the medicine, effects of quick pain relief and effective stone dissolution are realized, and the kidney stone can be effectively treated.
Owner:QINGDAO BAIRUIJI BIOTECH

Kidney stone prediction method and prediction system based on incremental neural network model

The invention discloses a method for predicting kidney stones based on an incremental neural network model, comprising the following steps: establishing a daily data database for kidney stones; training the neural network model; collecting daily life data and sending it to a server, and saving it to the user's daily data Record table; the data of the day is extracted from the user's daily data record table to form an n-dimensional vector. Greater than 0.5; the user judges that he has kidney stones, and the user goes to the hospital for examination by himself, and sends the examination results back to the server through the smart home kidney stone care equipment, and the server judges whether the examination results are correct; The network model is dynamically corrected. The prediction of the present invention is accurate, and the neural network model is tailored for each user.
Owner:湖南老码信息科技有限责任公司

Ultrasound system and method for detection of kidney stones using twinkling artifact

A method color Doppler imaging in accordance with some examples of the present disclosure includes transmitting with a probe of an ultrasound imaging system, ultrasound pulses towards a region of interest in a subject, receiving with the probe echoes responsive to the pulses, generating B-mode image data and Doppler signals based on the ultrasound echoes, filtering the Doppler signals, wherein thefiltering includes rejecting lower intensity signals which have amplitudes below a threshold amplitude and passing higher intensity signals which have amplitudes above the threshold amplitude, generating color data based on the higher intensity signals, overlaying the color data with the B-mode image data to produce a color Doppler image, and displaying the color Doppler image in a kidney stone detection interface.
Owner:KONINKLJIJKE PHILIPS NV

Modular wireless large bore vacuum universal endoscope and vacuumscope

The present technology relates to ureteroscopy, laser ablation of ureteral and renal stone, capture and removal of stone fragments. In one embodiment, the device includes an optical instrument operably connected to a large vacuum channel between 1.5 mm and 8.0 mm in width. In another embodiment, the device includes two single-time use disposable or potentially reusable units, such as a large vacuum endoscope removal tip and wireless and modular battery powered hand piece.
Owner:RGT UNIV OF CALIFORNIA

Scheme for treating ESWL postoperative complications based on stranguria-treating and stasis-removing prescription

The invention belongs to the technical field of medical treatment, and particularly relates to a scheme for treating ESWL postoperative complications based on a stranguria-treating and stasis-removing prescription, and the scheme comprises the following steps: S1, object selection: selecting 60 cases of patients received by a certain traditional Chinese medicine hospital; S2, carrying out experiment grouping: according to a random number table method, dividing the 60 patients selected in S1 into a control group and a treatment group; S3, patient treatment: treating the control group patients in S2 according to a first scheme; treating the patients in the treatment group according to the second scheme; S4, observing and detecting the patient: comparing the urine NAG level, the urine beta2M level, the clinical curative effect and the occurrence condition of complications of the patient; and S5, carrying out statistical analysis: observing the difference condition of the treatment indexes at different observation time points. By setting a control group and a treatment group and comparing the postoperative conditions of the two groups of patients, the stranguria-treating and stasis-removing prescription has a good treatment effect on kidney injury caused by kidney stone ESWL.
Owner:张楠

A kind of traditional Chinese medicine composition for treating kidney stones

The invention aims to provide a Chinese medicinal composition for treating kidney stone with remarkable treatment effect and short treatment period. The Chinese medicinal composition is prepared by mixing the following Chinese medicinal raw materials in part by weight: 18 to 22 parts of dendrobium, 18 to 22 parts of desmodium, 18 to 22 parts of adenophora elata, 12 to 18 parts of pyrrosia lingua,12 to 18 parts of chicken's gizzard-membrane, 18 to 22 parts of prepared rhizome of rehmannia, 12 to 18 parts of medlar, 8 to 12 parts of immature bitter orange, 12 to 18 parts of atractylodes lancea, 8 to 12 parts of phellodendron, 12 to 18 parts of dwarf lilyturf tuber, 12 to 18 parts of figwort root, 12 to 18 parts of twotooth achyranthes, 28 to 32 parts of the root of kudzu vine and 18 to 22 parts of clematis root. The Chinese medicinal composition can effectively improve the discharge rate of stone, reduce discharge time of stone and improve clinic symptoms and positive signs, is safe and effective in clinical use, free from toxic and side effects and effective for treating kidney stone and has a high clinic use value.
Owner:NANTONG HONGCI PHARMA

A Chinese medicinal composition for treating renal calculus and urinary calculus

A Chinese medicinal composition for treating renal calculus and urinary calculus is prepared from, by weight, herba Lysimachiae Christinae 17-23g, endothelium corneum gigeriae galli 12-18g, Artemisiaanomala 12-18g, Dioscorea Septemloba 12-18g, talc 17-23g, and mirabilite 12-18g. The traditional Chinese medicine combination of the invention can be used together and complement each other, and has remarkable effect on treating kidney calculus and urinary calculus.
Owner:林州市延年百龄中药科技有限公司

Simple bed for curing renal stone

The invention relates to a simple bed for curing renal stone, a rotating shaft is arranged on an inverted T-shaped bed frame, a bed board is arranged on the rotating shaft, the bed board is respectively provided with a pillow, a double shoulder belt, a chest belt, a crotch belt, a thigh belt and a foot belt; a semicircular gear is arranged below the bed board, and the semicircular gear is driven by a pinion arranged on a small motor arranged at the lower part of the bed frame; the small motor is controlled by a reversible switch at the bed head; a moving telescopic vibration massager is arranged at the top of the bed frame. As the bed is simple in structure, the manufacturing cost is low, the use cost is low and the use is convenient due to the suitability for self-help treatment at the home of a patient; the bed can be used as a common bed when a renal stone disease is treated or no renal stone disease is treated, and the bed can also be used as a massage bed.
Owner:马千里

Kidney calculus treating drug

InactiveCN105617125AAchieve the effect of washing, dissolving and excreting stonesMammal material medical ingredientsUrinary disorderPolygonum aviculareOyster
The present invention relates to a kidney calculus treating drug, which is characterized in that the raw materials in the formula comprise, by weight, 10-60 parts of cudrania cochin chinensis, 20-150 parts of paederia scandens, 10-35 parts of saururus chinensis, 5-15 parts of radix angelicae pubescentis, 10-40 parts of oyster, 10-30 parts of turtle shell, 5-25 parts of talc, 10-70 parts of lysimachia christinae hance, 5-25 parts of plantaginis semen, 5-20 parts of Shihua, 5-20 parts of polygonum aviculare, 3-10 parts of caulis clematidis armandii, 5-20 parts of cortex phellodendri, 10-35 parts of herba glechomae, 10-30 parts of chicken's gizzard membrane, 5-25 parts of lygodium japonicum, 5-25 parts of rhizoma dioscoreae hypoglaucae, 10-50 parts of coix seed, 5-15 parts of alisma orientalis, and 5-15 parts of dianthus superbus. The kidney calculus treating drug of the present invention has effects of kidney qi supplementing, urinary bladder qi conversion function increasing, normal urinary function promoting, calculus dissolving, calculus discharge, renal colic relieving, ureter smooth muscle spasm relieving, qi promoting, pain stopping, heat clearing, dampness removing and calculus discharge so as to rinse, melt and discharge the calculus.
Owner:周子童

Pharmaceutical composition for treating gall stone and kidney stone and preparation method thereof

The invention discloses a pharmaceutical composition for treating gall stone and kidney stone and a preparation method thereof. The pharmaceutical composition for treating gall stone and kidney stone comprises the following materials in parts by weight: 10-30 parts of white radishes, 5-20 parts of dried orange peel, 50-70 parts of lysimachia christinae hance, 5-20 parts of radix bupleuri, 40-60 parts of liquorice, 2-20 parts of rhizoma corydalis, 8-25 parts of radix curcumae, 8-25 parts of endothelium corneum gigeriae galli, 35-55 parts of polygonum aviculare and 20-40 parts of plantain herb. In the pharmaceutical composition for treating gall stone and kidney stone disclosed by the invention, the white radish and the dried orange peel serve as guiding drugs to effectively guide efficacies of other components in the traditional Chinese medicinal composition to reach diseased parts; especially, the use of white radish has good effect, clinical practice proves that the pharmaceutical composition, compared with a product not using white radish, is 11% higher in cure rate and 13% shorter in treatment course; therefore, the white radish plays a key role in the composition disclosed by the invention.
Owner:郝朝胜

Arrangement for filtering out damaging heat created from laser energy contacting a kidney stone

An arrangement that prevents carbonization of cladding, coating, or buffer layers of a surgical laser fiber due to thermal radiation reflected back into the fiber from, or emitted by, a target of the laser, includes a thermal radiation blocking, absorbing or diverting structure. The thermal radiation blocking, absorbing or diverting structure surrounds an end portion of the fiber that has been stripped of one or more coating and / or buffer layers, and may be made of a heat resistant material such as PTFE or polyimide to block heat from reaching the coating or buffer layers, an optical ferrule such as fused silica to guide the heat away from the fiber coating or buffer layers, or a high refraction index material such as UV adhesive.
Owner:OPTICAL INTEGRITY INC

An optical fiber sleeve for a holmium laser lithotripsy device that protects kidney tissue

The invention provides an optical fiber sleeve of a holmium laser lithotripsy device for protecting kidney tissue, belonging to the technical field of holmium laser lithotripsy devices. The optical fiber sleeve of the holmium laser lithotripsy equipment includes an optical fiber, a double-layer hollow optical fiber sleeve, a fiber filament rod, and a fiber filament fixing cap. The double-layer hollow optical fiber is sheathed with an outer layer film and an inner layer film, a hollow structure is formed between the inner layer film and the outer layer film, and a plurality of fiber filament rods are arranged, and a fiber filament rod is arranged inside the fiber filament rod. , its structure is the same as that of the double-layer hollow fiber sleeve. The two sides of the outer film of the double-layer hollow fiber sleeve are provided with a plurality of liquid outlet holes, and the angle between the two liquid outlet holes at the same height is 150-170 ° between. The invention has simple structure and low cost, does not affect the optical path of the optical fiber, has no complicated electronic structure, can be sterilized after use, reduces the use cost, and can greatly reduce the kidney damage of kidney stone patients.
Owner:HEFEI CURESTAR LASER DEVICE

Medical device and methods of use

The present disclosure is directed to a medical device. Systems and methods are provided for utilizing a laser to break a kidney stones into smaller fragments and / or dust, and removing particles, stone fragments and / or stone dust from a patient. The medical device may include a tube having a distal end and a proximal end, a first lumen extending from the proximal end to the distal end of the tube and in fluid communication with the distal end and a plurality of side ports located at a distal portion of the tube, and a second lumen extending from the proximal end to the distal end of the tube.
Owner:BOSTON SCI SCIMED INC

Information analysis method for treating kidney stone through radix astragali-gold mixture, computer equipment and application

The invention belongs to the technical field of network pharmacology and molecular docking, and discloses an information analysis method, computer equipment and application of a Qijin mixture for treating kidney stone, and the information analysis method comprises the following steps: acquiring effective components and disease targets of medicines by utilizing a plurality of databases, and taking intersection genes of the effective components and the disease targets; the method comprises the following steps: constructing a traditional Chinese medicine-component-target regulation and control network by using Cytoscape 3.8.0 software, and introducing an intersection target gene into a String database to construct a PPI network; carrying out topology analysis and GO and KEGG enrichment analysis on the intersection gene; and docking the active ingredients with the core gene molecules, calculating the minimum binding energy, and making a molecular docking model diagram. According to the application disclosed by the invention, the effective components of the astragalus membranaceus and the lysimachia christinae hance are analyzed through network pharmacology, the combination of the effective components of the medicines and a kidney stone target spot is verified by a molecular docking technology, and the potential action mechanism and action target spot of the astragalus membranaceus and the lysimachia christinae hance for treating the kidney stone are predicted; therefore, the radix astragali-gold mixture can be used for treating the kidney stone through a multi-target, multi-channel and multi-component way.
Owner:THE FIRST HOSPITAL OF HUNAN UNIV OF CHINESE MEDICINE (CLINICAL RES INST OF TRADITIONAL CHINESE MEDICINE)
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