The invention relates to a leukocyte extraction and classification method based on an improved K-means and a 
convolutional neural network. The method comprises the steps of firstly, selecting an initial clustering center according to 
cell image 
gray level distribution, and clustering all pixels of an image initially according to the principle of proximity; then, improving the 
Euclidean distance ofthe FWSA-KM 
algorithm; before the extraction of leukocytes, carrying out the 
color space decomposition firstly, and carrying out the 
cell nucleus and 
cytoplasm extraction by adopting a color component beneficial to leukocyte segmentation and an improved K-means 
algorithm; separating a complex adhesion part by adopting a 
watershed algorithm; and finally, performing classification based on the 
convolutional neural network. According to the method, the leukocyte 
nucleus segmentation precision and the 
cytoplasm segmentation precision are 95.81% and 91.28% respectively, and compared with a traditional segmentation method, the precisions are greatly improved, the classification accuracy can reach 98.96% at most, the classification average time is 0.39 s, and compared with an existing leukocyteclassification algorithm, the CNN classification method not only has obvious advantages, but also has the great improvement space.