39results about How to "Broad-spectrum high-efficiency antibacterial effect" patented technology

Belonging to the technical field of biomedicine, the invention in particular relates to a natural antibacterial peptide QHA and application thereof. The natural antibacterial peptide QHA is composed of 30 amino acid residues, is straight chain polypeptide, and has a molecular weight of 3628.5Da and isoelectric point of 12.61. The antibacterial peptide QHA provided by the invention has the beneficial characteristics of small molecular weight, simple chemical synthesis method, efficient, broad-spectrum and efficient antibacterial action, and good stability, etc., thus having broad application prospects. In addition, the invention also relates to a coding gene of antibacterial peptide QHA and application thereof.

The present invention relates to a strain for food preservation and its antibacterial product, belonging to the field of food bio-technology. The antibacterial product produced by Bacillus subtilis strain fmbJ has obvious depressing effect for main pathogenic bacteria and putrefactive bacteria in the food, including 7 Gram-negative bacteria, 3 Gram-positive bacteria and 4 moulds. Its production process includes the steps: slope, shave-flask seed, seed tank, fermentation tank, separation extraction and antibacterial metabolic product.

The invention relates to a streptomyces antibacteria product and a method for manufacturing the same, belonging to the biotechnology field. GB-2 seeds of the streptomyces are proliferated and cultivated, then inoculated to undergo submerged ferment under 28 DEG C for 144-168 hours, then the fermentation liquor is filtrated, n-hexane and ethyl acetate is used for twice extractions to eliminate the lipid fat-soluble impurities, and then an ultrafiltration membrane is used to intercept the biological molecules with the molecular weight below 1,000, the filter liquor is made pass through a 1-2nm nanometer filtration membrane to obtain the antibacterial metabolic product. As proved by test, the antibacterial substance has the broad-spectrum antibacterial activity against bacteria and epiphyte, as well as the significant antibacterial activity against multiple pathogenic organisms and spoilage organisms. The antibacterial product provided by the invention has significant inhibitive effect on multiple pathogenic bacterium and moulds, thereby manifesting the efficient and broad-spectrum activity, simple method and low cost, with high applicable value and great prospect in the market in the respect of antiseptics, forage additives and medicine.

The invention relates to the field of clothing, in particular to a piece of antibacterial, mosquito-and-insect-repellent functional loungewear. The antibacterial, mosquito-and-insect-repellent functional loungewear is characterized in that silver ion antibacterial agent and permethrin mosquito-and-insect-repellent finishing agent are used for processing a textile, and the processing steps are fabric preprocessing, finishing solution preparation, padding, drying, preshrinking and clothing making. The antibacterial, mosquito-and-insect-repellent functional loungewear has a broad-spectrum, high-effective antibacterial effect on a variety of harmful bacteria, such as staphylococcus aureus, pneumobacillus, colibacillus, pseudomonas aeruginosa, candida albicans and trichophyton mentagrophytes, the bacteria inhibition rate of the antibacterial, mosquito-and-insect-repellent functional loungewear on staphylococcus aureus and other harmful bacteria still reaches more than 99 percent after the antibacterial, mosquito-and-insect-repellent functional loungewear is washed for 100 times, the stay and bite of mosquitoes are effectively reduced, the antibacterial, mosquito-and-insect-repellent functional loungewear has repelling and killing effects on various mosquitoes and insects, such as culex, aedes aegypti, tick and bedbug, and the loungewear made of the fabric has remarkable antibacterial, deodorizing, itch-relieving and mosquito-and-insect-repellent functions.

The invention discloses a Yangtze alligator antimicrobial peptide Alligatorin 6 as well as an amino acid sequence thereof and an application of the Yangtze alligator antimicrobial peptide Alligatorin 6 in antibiosis. The antimicrobial peptide Alligatorin 6 is a mature peptide sequence of the antimicrobial peptide which is obtained by searching a Yangtze alligator gene database by virtue of screening and analyzing, wherein an amino acid sequence of the mature peptide sequence is as shown in a sequence table SEQ ID NO.1. By virtue of analysis and comparison, the Yangtze alligator antimicrobial peptide Alligatorin 6 has obvious difference from the amino acid sequences of all of the existing known antimicrobial peptides, and belongs to a novel antimicrobial peptide. According to an antimicrobial test, the Yangtze alligator antimicrobial peptide Alligatorin 6 has very strong antimicrobial activity on gram positive bacteria and gram negative bacteria, is broad-spectrum and efficient in antimicrobial action. Besides, the Yangtze alligator antimicrobial peptide Alligatorin 6 has the characteristics of low hemolytic activity, good salt tolerance, good heat tolerance and good heat stability, and can be applied to the fields of medicines, cosmetics, food fresh keeping and breeding industry.

The invention discloses a preserving fluid of a collagen mask. According to a formula of the preserving fluid of the collagen mask, each 100 mL of distilled water contains the following ingredients: 0.10-10.00 g of a bonded compound of hyaluronic acid and antibacterial peptide, 0.05-0.4 g of a skin-whitening agent, 0.05-0.4 g of a cutin softener, 0.05-0.4 g of a skin anti-wrinkling agent, 0.2-1.2 g of a skin repairing agent and 0.2-2 g of aromatic. The collagen mask of the invention can be used along with existing collagen masks in the market and also can be marketed alone; the bonded compound of hyaluronic acid and antibacterial peptide in the formula is a non-irritating broad-spectrum antibacterial disinfector, is safe and nonirritating, and has high stability; and the collagen mask obtained after being immersed in the preserving fluid will not produce irritating feelings such as stabbing pain and the like on face and has a moisturizing function and can perform a beauty treatment effect to the greatest extent.

The invention discloses a nano-polymer antibacterial agent and a preparation method thereof. A nano polymer product with an antibacterial function is directly obtained by using an organic nano technology of emulsion polymerization via a one-step process. The obtained product has large specific surface area and high utilization rate, the particle size of the obtained product is within the range of 40-90nm; meanwhile, the antibacterial agent contains positive charges at the surface; harmful microbe can be firmly captured; the physiological process is interfered; a long fatty chain at the surface of the antibacterial agent punctures and destroys a cell wall, thereby resulting in death. Thus, the broad-spectrum efficient antibacterial effect is achieved, and the nano-polymer antibacterial agent has the characteristic of contact sterilization. In addition, the product disclosed by the invention is stable in structure, not easy to migrate, easy to disperse, good in compatibility with a polymer material, wide in application range and low in cost.

The invention discloses application of a natural antibacterial peptide As-CATH4 in food preservation and fresh-keeping. The natural antibacterial peptide As-CATH4 in the present invention has a broad-spectrum and high-efficiency antibacterial effect on common food spoilage bacteria, has a rapid sterilization effect, and has a good synergistic effect with a traditional preservative butyl p-hydroxybenzoate. The combination of As-CATH4 and butyl p-hydroxybenzoate significantly inhibits the growth of spoilage bacteria, increases sensory evaluation score, and prolongs food storage time. In the storage experiment of salmon meat, cooked meat sauce and freshly squeezed fruit juice, As-CATH4 significantly inhibits the growth of spoilage bacteria, increases sensory evaluation score, and prolongs food storage time. In the storage experiment of orange juice, the combination of As-CATH4 and butyl p-hydroxybenzoate significantly inhibits the growth of spoilage bacteria, prolongs food storage time, and shows a good synergistic effect. In addition, As-CATH4 can be completely degraded by trypsin and has no toxic side effects on human body. As a new type of food preservative, As-CATH4 has wide application prospects.

The invention relates to an application of natural host defensin Cm-CATH2, in particular to an application of natural host defensin Cm-CATH2 to preparation of medicines for resisting aquatic product pathogenic bacteria, and an application of the natural host defensin Cm-CATH2 to preparation of an aquaculture animal immunization adjusting agent. The invention further discloses an application of thenatural host defensin Cm-CATH2 to preparation of an aquaculture animal feed. Research results that micropterus salmoides are used as experiment animals indicate that the Cm-CATH2 can kill varied common aquatic product pathogenic bacteria, can adjust the immune function of the micropterus salmoides, can improve the bacterial infection resistance of the micropterus salmoides, and can increase the motility rate of the micropterus salmoides. The Cm-CATH2 has broad application prospects in the field of aquaculture.

The invention discloses application of a natural antibacterial peptide Hc-CATH in food preservation and fresh-keeping. The natural antibacterial peptide Hc-CATH in the present invention has a broad-spectrum and high-efficiency antibacterial effect on common food spoilage bacteria, has a rapid sterilization effect, and has a good synergistic effect with a traditional preservative butyl p-hydroxybenzoate. The combination of Hc-CATH and butyl p-hydroxybenzoate significantly inhibits the growth of spoilage bacteria, increases sensory evaluation score, and prolongs food storage time. In the storageexperiment of salmon meat, cooked meat sauce and freshly squeezed fruit juice, Hc-CATH significantly inhibits the growth of spoilage bacteria, increases sensory evaluation score, and prolongs food storage time. In the storage experiment of orange juice, the combination of Hc-CATH and butyl p-hydroxybenzoate significantly inhibits the growth of spoilage bacteria, prolongs food storage time, and shows a good synergistic effect. In addition, Hc-CATH can be completely degraded by trypsin and has no toxic side effects on human body. As a new type of food preservative, Hc-CATH has wide applicationprospects.

The invention relates to application of a natural host defense peptide Hc-CATH, in particular to application of the natural host defense peptide Hc-CATH in preparation of a medicine resisting aquaticpathogenic bacteria and application in the preparation of an aquaculture animal immunomodulator. The invention further discloses application of the natural host defense peptide Hc-CATH in preparationof aquaculture animal feed. The research results using largemouth bass as experimental animals show that the Hc-CATH can kill a variety of common aquatic pathogens, regulate the immune function of largemouth bass, improve the resistance of largemouth bass to bacterial infections, and improve the survival rate of the largemouth bass. The Hc-CATH has wide application prospects in the field of aquaculture.

The invention discloses an antibacterial peptide MS-CATH from Miniopterus fuliginosus and an application thereof in the antibacterial aspect. The antibacterial peptide MS-CATH disclosed by the invention is derived from the Miniopterus fuliginosus. A mature peptide sequence of the antibacterial peptide is obtained by searching a gene database of the Miniopterus fuliginosus and screening and analyzing, and the amino acid sequence of the antibacterial peptide is shown as SEQ ID NO.1 in a sequence table. Through contrastive analysis, the natural antibacterial peptide MS-CATH is obviously different from the amino acid sequences of all known antibacterial peptides at present, and belongs to a novel antibacterial peptide. An antibacterial experiment result shows that the antibacterial peptide MS-CATH disclosed by the invention has extremely strong antibacterial activity on gram-positive bacteria, gram-negative bacteria and fungi, is rapid in bactericidal effect, has the characteristic of low hemolytic activity, and can be applied to preparation of drugs for resisting bacteria and inhibiting bacterial growth, preservatives, veterinary drugs, animal feeds and cosmetics.