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39results about How to "Broad-spectrum high-efficiency antibacterial effect" patented technology
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Natural antibacterial peptide and application thereof
ActiveCN104497119ASmall molecular weightThe chemical synthesis method is simpleAntibacterial agentsCosmetic preparationsChemical synthesisIsoelectric point
Belonging to the technical field of biomedicine, the invention in particular relates to a natural antibacterial peptide QHA and application thereof. The natural antibacterial peptide QHA is composed of 30 amino acid residues, is straight chain polypeptide, and has a molecular weight of 3628.5Da and isoelectric point of 12.61. The antibacterial peptide QHA provided by the invention has the beneficial characteristics of small molecular weight, simple chemical synthesis method, efficient, broad-spectrum and efficient antibacterial action, and good stability, etc., thus having broad application prospects. In addition, the invention also relates to a coding gene of antibacterial peptide QHA and application thereof.
Owner:王义鹏
Natural antimicrobial peptide Alligatorin4 and application thereof
ActiveCN104151415ABroad-spectrum high-efficiency antibacterial effectSmall molecular weightAntibacterial agentsCosmetic preparationsPreservativeHeat stability
The invention discloses a natural antimicrobial peptide Alligatorin4 and an application thereof in the antimicrobial aspect. The antimicrobial peptide Alligatorin4 disclosed by the invention is derived from Alligator sinensis. The mature peptide sequence of the antimicrobial peptide is obtained by retrieving a gene database of the Alligator sinensis, screening and analyzing, and the amino acid sequence is as shown in SEQ ID NO. 1 in a sequence table. By comparative analysis, the natural antimicrobial peptide Alligatorin4 is obviously different from the amino acid sequences of all the existing antimicrobial peptides, and belongs to a novel antimicrobial peptide. Antimicrobial experimental results show that the antimicrobial peptide Alligatorin4 disclosed by the invention has very strong antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria and fungi, has broad-spectrum and efficient antimicrobial effect, has the characteristics of low hemolytic activity, good salt tolerance, good heat tolerance, good heat stability and the like, and can be applied in preparation of medicines for resisting bacteria and inhibiting the growth of bacteria, preservatives, veterinary medicines, animal feeds and cosmetics.
Owner:SUZHOU UNIV
Strain for food preservation and its anti-bacterial product
InactiveCN1477189ABroad antibacterial spectrumControl microbial growthBiocideBacteriaFood biotechnologyMicrobiological growth
The present invention relates to a strain for food preservation and its antibacterial product, belonging to the field of food bio-technology. The antibacterial product produced by Bacillus subtilis strain fmbJ has obvious depressing effect for main pathogenic bacteria and putrefactive bacteria in the food, including 7 Gram-negative bacteria, 3 Gram-positive bacteria and 4 moulds. Its production process includes the steps: slope, shave-flask seed, seed tank, fermentation tank, separation extraction and antibacterial metabolic product.
Owner:NANJING AGRICULTURAL UNIVERSITY
Streptomycete antimicrobial production and method of preparing the same
InactiveCN101153287ABroad-spectrum high-efficiency antibacterial effectBroad antibacterial spectrumAntibacterial agentsBiocideBacteroidesFiltration membrane
The invention relates to a streptomyces antibacteria product and a method for manufacturing the same, belonging to the biotechnology field. GB-2 seeds of the streptomyces are proliferated and cultivated, then inoculated to undergo submerged ferment under 28 DEG C for 144-168 hours, then the fermentation liquor is filtrated, n-hexane and ethyl acetate is used for twice extractions to eliminate the lipid fat-soluble impurities, and then an ultrafiltration membrane is used to intercept the biological molecules with the molecular weight below 1,000, the filter liquor is made pass through a 1-2nm nanometer filtration membrane to obtain the antibacterial metabolic product. As proved by test, the antibacterial substance has the broad-spectrum antibacterial activity against bacteria and epiphyte, as well as the significant antibacterial activity against multiple pathogenic organisms and spoilage organisms. The antibacterial product provided by the invention has significant inhibitive effect on multiple pathogenic bacterium and moulds, thereby manifesting the efficient and broad-spectrum activity, simple method and low cost, with high applicable value and great prospect in the market in the respect of antiseptics, forage additives and medicine.
Owner:NANJING AGRICULTURAL UNIVERSITY
Antibacterial, mosquito-and-insect-repellent functional loungewear
InactiveCN102628217ABroad-spectrum high-efficiency antibacterial effectReduce stayFibre treatmentStaphylococcus cohniiAedes aegypti
The invention relates to the field of clothing, in particular to a piece of antibacterial, mosquito-and-insect-repellent functional loungewear. The antibacterial, mosquito-and-insect-repellent functional loungewear is characterized in that silver ion antibacterial agent and permethrin mosquito-and-insect-repellent finishing agent are used for processing a textile, and the processing steps are fabric preprocessing, finishing solution preparation, padding, drying, preshrinking and clothing making. The antibacterial, mosquito-and-insect-repellent functional loungewear has a broad-spectrum, high-effective antibacterial effect on a variety of harmful bacteria, such as staphylococcus aureus, pneumobacillus, colibacillus, pseudomonas aeruginosa, candida albicans and trichophyton mentagrophytes, the bacteria inhibition rate of the antibacterial, mosquito-and-insect-repellent functional loungewear on staphylococcus aureus and other harmful bacteria still reaches more than 99 percent after the antibacterial, mosquito-and-insect-repellent functional loungewear is washed for 100 times, the stay and bite of mosquitoes are effectively reduced, the antibacterial, mosquito-and-insect-repellent functional loungewear has repelling and killing effects on various mosquitoes and insects, such as culex, aedes aegypti, tick and bedbug, and the loungewear made of the fabric has remarkable antibacterial, deodorizing, itch-relieving and mosquito-and-insect-repellent functions.
Owner:王建波
Yangtze alligator antimicrobial peptide Alligatorin 6 and application thereof
ActiveCN104177485ABroad-spectrum high-efficiency antibacterial effectSmall molecular weightAntibacterial agentsCosmetic preparationsAntimicrobial actionHeat stability
The invention discloses a Yangtze alligator antimicrobial peptide Alligatorin 6 as well as an amino acid sequence thereof and an application of the Yangtze alligator antimicrobial peptide Alligatorin 6 in antibiosis. The antimicrobial peptide Alligatorin 6 is a mature peptide sequence of the antimicrobial peptide which is obtained by searching a Yangtze alligator gene database by virtue of screening and analyzing, wherein an amino acid sequence of the mature peptide sequence is as shown in a sequence table SEQ ID NO.1. By virtue of analysis and comparison, the Yangtze alligator antimicrobial peptide Alligatorin 6 has obvious difference from the amino acid sequences of all of the existing known antimicrobial peptides, and belongs to a novel antimicrobial peptide. According to an antimicrobial test, the Yangtze alligator antimicrobial peptide Alligatorin 6 has very strong antimicrobial activity on gram positive bacteria and gram negative bacteria, is broad-spectrum and efficient in antimicrobial action. Besides, the Yangtze alligator antimicrobial peptide Alligatorin 6 has the characteristics of low hemolytic activity, good salt tolerance, good heat tolerance and good heat stability, and can be applied to the fields of medicines, cosmetics, food fresh keeping and breeding industry.
Owner:宜肌坊(厦门)生物科技有限公司
Reptile antibacterial peptide Alligatorin5 and applications thereof
ActiveCN104163861ABroad-spectrum high-efficiency antibacterial effectSmall molecular weightAntibacterial agentsCosmetic preparationsChinese alligatorAntibacterial activity
The invention discloses a reptile-derived antibacterial peptide Alligatorin5, an amino acid sequence thereof and applications of the antibacterial peptide in the antibacterial field. The antibacterial peptide Alligatorin5 is derived from Chinese alligator. By searching a Chinese alligator gene database, screening and analyzing, a mature peptide sequence of the antibacterial peptide is obtained. The amino acid sequence of the antibacterial peptide Alligatorin5 is shown as SEQ ID NO.1 in a sequence table. By comparative analysis, the antibacterial peptide Alligatorin5 is obviously different from amino acid sequences of antibacterial peptides known at present, and belongs to a novel antibacterial pepetide. Antibacterial experiments show that: the antibacterial peptide Alligatorin5 has high antibacterial activity for gram positive bacteria, gram negative bacteria and funguses, and is broad in antibacterial spectrum and efficient; the antibacterial peptide Alligatorin5 has characteristics of low hemolytic activity, salt tolerance, heat tolerance, good thermal stability, and the like, and can be used for the fields of medicines, cosmetics, food fresh-keeping and the breeding industry.
Owner:SUZHOU UNIV
Application of natural host defense peptides Alligatorin4
ActiveCN107252475AEnhance immune functionImprove survival rateAntibacterial agentsPeptide/protein ingredientsZoologyAquaculture
The invention relates to application of natural host defense peptides Alligatorin4 to preparing aquatic pathogenic bacterium resistant medicines, aquaculture animal immunity activators and aquaculture animal feed. The application has the advantages that as shown by results of research on Chinese mitten crab which is an experimental animal, immunity functions of the Chinese mitten crab can be enhanced by the natural host defense peptides Alligatorin4, the bacterial infection resistance of the Chinese mitten crab can be improved, and the survival rate of the Chinese mitten crab can be increased; the natural host defense peptides Alligatorin4 have broad application prospects in the field of aquaculture.
Owner:思格(苏州)生物科技有限公司
Antibacterial functional medical textile
InactiveCN102912632ABroad-spectrum high-efficiency antibacterial effectReduce stayFibre treatmentEscherichia coliAedes aegypti
The invention relates to the clothing field, particularly to an antibacterial functional medical textile. The textile is characterized in that a silver ion antibacterial agent, a soil-releasing finishing agent and a permethrin mosquito repellent finishing agent are used for processing the textile to enable the textile to acquire antibacterial, soil-releasing and mosquito repellent functions. A processing method includes processing fabric into a semi-product for after-treatment after steps of pretreatment, dyeing or printing and the like; preparing a functional finishing agent which is antibacterial, soil-releasing and mosquito repellent; padding the working solution; drying; baking; packaging; and manufacturing leisure wear. The textile has broad-spectrum high-effect antibacterial functions on a plurality of harmful bacteria such as staphylococcus aureus, pneumobacillus, escherichia coli, pseudomonas aeruginosa, monilia albican and trichophyton mentagrophytes, the bacteriostasis rate of the textile for the harmful bacteria such as staphylococcus aureus after washed for 100 times can still reach above 99%, stay and biting of mosquitoes can be reduced effectively, repellent and contact toxicity functions can be performed on various mosquitoes such as culex, Aedes aegypti, ticks and bugs, and the leisure wear made of the textile is provided with obvious antibacterial, deodorant, itching relieving and mosquito repellent functions.
Owner:王建波
Preserving fluid of collagen mask
InactiveCN105616309AQuick killLower resistanceCosmetic preparationsToilet preparationsAdditive ingredientWhitening Agents
The invention discloses a preserving fluid of a collagen mask. According to a formula of the preserving fluid of the collagen mask, each 100 mL of distilled water contains the following ingredients: 0.10-10.00 g of a bonded compound of hyaluronic acid and antibacterial peptide, 0.05-0.4 g of a skin-whitening agent, 0.05-0.4 g of a cutin softener, 0.05-0.4 g of a skin anti-wrinkling agent, 0.2-1.2 g of a skin repairing agent and 0.2-2 g of aromatic. The collagen mask of the invention can be used along with existing collagen masks in the market and also can be marketed alone; the bonded compound of hyaluronic acid and antibacterial peptide in the formula is a non-irritating broad-spectrum antibacterial disinfector, is safe and nonirritating, and has high stability; and the collagen mask obtained after being immersed in the preserving fluid will not produce irritating feelings such as stabbing pain and the like on face and has a moisturizing function and can perform a beauty treatment effect to the greatest extent.
Owner:刘志刚
Migration-free antibacterial cellulose-based foam and preparation method thereof
The invention discloses migration-free antibacterial cellulose-based foam. The migration-free antibacterial cellulose-based foam is prepared from the following raw materials in parts by weight: 95 to 99 parts of water, 1 to 5 parts of cellulose, 0.1 to 0.3 part of a wet strengthening agent, 0.1 to 0.5 part of a surfactant, 0.01 to 0.2 part of a cross-linking agent and 0.03 to 0.2 part of an antibacterial agent. A migration-free antibacterial cellulose-based foam product is prepared through the following steps: mixing the weighed cellulose and water and defibering; (2) adding the wet strengthening agent, the surfactant, the cross-linking agent and the antibacterial agent, which are weighed in step (1), into a substance obtained by defibering; mixing and stirring, and filtering; drying for 8h to 48h at temperature in a range from room temperature to 60 DEG C. A preparation process of the migration-free antibacterial cellulose-based foam is simple and environmentally friendly; extra equipment is not needed and the product can be produced by a standard papermaking basic facility, so that the preparation process is suitable for industrial production.
Owner:GUANGXI UNIV
Nano-polymer antibacterial agent and preparation method thereof
InactiveCN103694401ABroad-spectrum high-efficiency antibacterial effectLarger than surfaceBiocideAntifouling/underwater paintsAnti bacterialBroad spectrum
The invention discloses a nano-polymer antibacterial agent and a preparation method thereof. A nano polymer product with an antibacterial function is directly obtained by using an organic nano technology of emulsion polymerization via a one-step process. The obtained product has large specific surface area and high utilization rate, the particle size of the obtained product is within the range of 40-90nm; meanwhile, the antibacterial agent contains positive charges at the surface; harmful microbe can be firmly captured; the physiological process is interfered; a long fatty chain at the surface of the antibacterial agent punctures and destroys a cell wall, thereby resulting in death. Thus, the broad-spectrum efficient antibacterial effect is achieved, and the nano-polymer antibacterial agent has the characteristic of contact sterilization. In addition, the product disclosed by the invention is stable in structure, not easy to migrate, easy to disperse, good in compatibility with a polymer material, wide in application range and low in cost.
Owner:SOUTH CHINA AGRI UNIV
Application of natural antibacterial peptide As-CATH4 in food preservation and fresh-keeping
ActiveCN111374168AExtended storage timeGrowth inhibitionMeat/fish preservation using chemicalsAgainst vector-borne diseasesBiotechnologyMeat paste
The invention discloses application of a natural antibacterial peptide As-CATH4 in food preservation and fresh-keeping. The natural antibacterial peptide As-CATH4 in the present invention has a broad-spectrum and high-efficiency antibacterial effect on common food spoilage bacteria, has a rapid sterilization effect, and has a good synergistic effect with a traditional preservative butyl p-hydroxybenzoate. The combination of As-CATH4 and butyl p-hydroxybenzoate significantly inhibits the growth of spoilage bacteria, increases sensory evaluation score, and prolongs food storage time. In the storage experiment of salmon meat, cooked meat sauce and freshly squeezed fruit juice, As-CATH4 significantly inhibits the growth of spoilage bacteria, increases sensory evaluation score, and prolongs food storage time. In the storage experiment of orange juice, the combination of As-CATH4 and butyl p-hydroxybenzoate significantly inhibits the growth of spoilage bacteria, prolongs food storage time, and shows a good synergistic effect. In addition, As-CATH4 can be completely degraded by trypsin and has no toxic side effects on human body. As a new type of food preservative, As-CATH4 has wide application prospects.
Owner:SUZHOU UNIV
Sinonatrix annularis source antibacterial peptide SAC and application
ActiveCN104945494ASmall molecular weightThe chemical synthesis method is simpleAntibacterial agentsBiocideChemical synthesisCombinatorial chemistry
The invention belongs to the technical field of biomedicine, and particularly relates to sinonatrix annularis source antibacterial peptide SAC and application. The sinonatrix annularis source antibacterial peptide SAC is composed of 29 amino acid residues, and is linear chain peptide, the molecular weight is 3569.5 Da, and the isoelectric points are 11.59. The antibacterial peptide SAC has the advantages of being small in molecular weight, simple in chemical synthesis method, efficient in antibacterial action broad spectrum and low in hemolytic performance, and has the wide application prospect. In addition, an encoding gene and application of the SAC are related to.
Owner:WEIFANG UNIV OF SCI & TECH
Application of natural host defensin Cm-CATH2
PendingCN111658761ABroad-spectrum high-efficiency antibacterial effectImprove bactericidal effectAntibacterial agentsPeptide/protein ingredientsAnimal feedImmunologic function
The invention relates to an application of natural host defensin Cm-CATH2, in particular to an application of natural host defensin Cm-CATH2 to preparation of medicines for resisting aquatic product pathogenic bacteria, and an application of the natural host defensin Cm-CATH2 to preparation of an aquaculture animal immunization adjusting agent. The invention further discloses an application of thenatural host defensin Cm-CATH2 to preparation of an aquaculture animal feed. Research results that micropterus salmoides are used as experiment animals indicate that the Cm-CATH2 can kill varied common aquatic product pathogenic bacteria, can adjust the immune function of the micropterus salmoides, can improve the bacterial infection resistance of the micropterus salmoides, and can increase the motility rate of the micropterus salmoides. The Cm-CATH2 has broad application prospects in the field of aquaculture.
Owner:SUZHOU UNIV
Special fabric for pediatric patient clothes and preparation method of fabric
InactiveCN112458748AThe modification process is convenient and efficientGood water solubilityBiochemical fibre treatmentFilament/thread formingPolyesterYarn
The invention provides a fabric special for pediatric patient clothes and a preparation method of the fabric. The special fabric for the pediatric patient clothes is a single-layer fabric or a double-layer fabric obtained by blending and weaving antibacterial and antiviral cotton yarns and moisture-conducting and antibacterial polyester yarns. The antibacterial and antiviral cotton yarns are formed by compounding a silver-loaded fullerene derivative / titanium dioxide composite material with cotton yarns through dipping and padding processes. The moisture-conducting and antibacterial polyester yarns are prepared by carrying out low-temperature plasma pretreatment and fiber yarn forming treatment on polyester fibers with special-shaped cross sections, wherein the polyester fibers are formed by blending granulation and melt spinning of polyhexamethylene guanidine hydrochloride and polyester fiber master batches. The prepared special fabric for the pediatric patient clothes has excellent antibacterial and antiviral performance while having excellent hydrophilic performance and moisture conductivity.
Owner:郑程程
Processing technology of medical insect-proof and odor-resisting textile fabric
InactiveCN108867022ABroad-spectrum high-efficiency antibacterial effectReduce stayBiochemical fibre treatmentEscherichia coliAedes aegypti
The invention relates to the field of clothing and in particular relates to a processing technology of a medical insect-proof and odor-resisting textile fabric. The processing technology comprises thefollowing processing steps: carrying out steps of pre-treating, dyeing or printing and the like on a fabric to obtain a semi-finished product and waiting for after-finishing treatment; preparing finishing liquid with antibacterial, stain-releasing and anti-mosquito functions; padding a working solution; drying; pre-shrinking and packaging. The medical insect-proof and odor-resisting textile fabric provided by the invention has a broad-spectrum and efficient antibacterial effect on various harmful bacteria including staphylococcus aureus, pneumobacillus, escherichia coli, pseudomonas aeruginosa, candida sporogenes, trichophyton mentagrophytes and the like, is used for effectively reducing staying and biting of mosquitoes and has dispelling and contact killing effects on various mosquitoes,such as culex mosquitoes, aedes aegypti mosquitoes, ticks and bugs; loungewear produced by the fabric has remarkable antibacterial, odor-resisting, itching-relieving and anti-mosquito functions.
Owner:NANTONG WEILI TEXTILE CO LTD
Strain for food preservation and its anti-bacterial product
InactiveCN1216146CBroad-spectrum high-efficiency antibacterial effectGood antibacterial effectBiocideBacteriaFermentationFood products
Owner:NANJING AGRICULTURAL UNIVERSITY
Corrugated pipe raw material composition, preparation method thereof and pipe
The invention discloses a corrugated pipe raw material composition, a preparation method thereof and a pipe, and belongs to the technical field of pipes. The corrugated pipe raw material composition comprises the following components in percentage by mass: 63%-92.8% of polypropylene, 5%-25% of polymethyl methacrylate, 1%-5% of 1, 2-polybutadiene, 1%-5% of maleic anhydride, 0.1%-1% of a light stabilizer and 0.1%-1% of an antibacterial agent, wherein the light stabilizer is 2-(2 '-hydroxy-3'-tert-butyl-5 '-methylphenyl)-5-chlorobenzotriazole; and the antibacterial agent is silver loaded zirconium phosphate. The corrugated pipe raw material composition provided by the embodiment of the invention solves the technical problem that the coexistence of the ring stiffness and the ring flexibility of the pipe is difficult to reach the standard, improves the physical and chemical properties and the yield of the pipe, is beneficial to the falling of the manufacturing cost of the pipe, and prolongsthe service life of the pipe.
Owner:JIANGXI TIANFENG CONSTR GRP PLASTIC STEELTECH
A kind of Chinese alligator antimicrobial peptide alligatorin6 and its application
ActiveCN104177485BBroad-spectrum high-efficiency antibacterial effectSmall molecular weightAntibacterial agentsCosmetic preparationsAntimicrobial actionChinese alligator
The invention discloses a Yangtze alligator antimicrobial peptide Alligatorin 6 as well as an amino acid sequence thereof and an application of the Yangtze alligator antimicrobial peptide Alligatorin 6 in antibiosis. The antimicrobial peptide Alligatorin 6 is a mature peptide sequence of the antimicrobial peptide which is obtained by searching a Yangtze alligator gene database by virtue of screening and analyzing, wherein an amino acid sequence of the mature peptide sequence is as shown in a sequence table SEQ ID NO.1. By virtue of analysis and comparison, the Yangtze alligator antimicrobial peptide Alligatorin 6 has obvious difference from the amino acid sequences of all of the existing known antimicrobial peptides, and belongs to a novel antimicrobial peptide. According to an antimicrobial test, the Yangtze alligator antimicrobial peptide Alligatorin 6 has very strong antimicrobial activity on gram positive bacteria and gram negative bacteria, is broad-spectrum and efficient in antimicrobial action. Besides, the Yangtze alligator antimicrobial peptide Alligatorin 6 has the characteristics of low hemolytic activity, good salt tolerance, good heat tolerance and good heat stability, and can be applied to the fields of medicines, cosmetics, food fresh keeping and breeding industry.
Owner:宜肌坊(厦门)生物科技有限公司
A kind of natural antibacterial peptide and its application
ActiveCN104497119BSmall molecular weightThe chemical synthesis method is simpleAntibacterial agentsBiocideAntimicrobial actionChemical synthesis
Belonging to the technical field of biomedicine, the invention in particular relates to a natural antibacterial peptide QHA and application thereof. The natural antibacterial peptide QHA is composed of 30 amino acid residues, is straight chain polypeptide, and has a molecular weight of 3628.5Da and isoelectric point of 12.61. The antibacterial peptide QHA provided by the invention has the beneficial characteristics of small molecular weight, simple chemical synthesis method, efficient, broad-spectrum and efficient antibacterial action, and good stability, etc., thus having broad application prospects. In addition, the invention also relates to a coding gene of antibacterial peptide QHA and application thereof.
Owner:王义鹏
Streptomycete antimicrobial production and method of preparing the same
InactiveCN101153287BBroad-spectrum high-efficiency antibacterial effectBroad antibacterial spectrumAntibacterial agentsBiocideBacteroidesFeed additive
Owner:NANJING AGRICULTURAL UNIVERSITY
Application of natural antibacterial peptide Hc-CATH in food preservation and fresh-keeping
ActiveCN111374317AExtended storage timeGrowth inhibitionAgainst vector-borne diseasesFood scienceBiotechnologyMeat paste
The invention discloses application of a natural antibacterial peptide Hc-CATH in food preservation and fresh-keeping. The natural antibacterial peptide Hc-CATH in the present invention has a broad-spectrum and high-efficiency antibacterial effect on common food spoilage bacteria, has a rapid sterilization effect, and has a good synergistic effect with a traditional preservative butyl p-hydroxybenzoate. The combination of Hc-CATH and butyl p-hydroxybenzoate significantly inhibits the growth of spoilage bacteria, increases sensory evaluation score, and prolongs food storage time. In the storageexperiment of salmon meat, cooked meat sauce and freshly squeezed fruit juice, Hc-CATH significantly inhibits the growth of spoilage bacteria, increases sensory evaluation score, and prolongs food storage time. In the storage experiment of orange juice, the combination of Hc-CATH and butyl p-hydroxybenzoate significantly inhibits the growth of spoilage bacteria, prolongs food storage time, and shows a good synergistic effect. In addition, Hc-CATH can be completely degraded by trypsin and has no toxic side effects on human body. As a new type of food preservative, Hc-CATH has wide applicationprospects.
Owner:SUZHOU UNIV
Application of natural host defense peptide Hc-CATH
PendingCN111658762ABroad-spectrum high-efficiency antibacterial effectImprove bactericidal effectAntibacterial agentsPeptide/protein ingredientsAnimal feedPathogen
The invention relates to application of a natural host defense peptide Hc-CATH, in particular to application of the natural host defense peptide Hc-CATH in preparation of a medicine resisting aquaticpathogenic bacteria and application in the preparation of an aquaculture animal immunomodulator. The invention further discloses application of the natural host defense peptide Hc-CATH in preparationof aquaculture animal feed. The research results using largemouth bass as experimental animals show that the Hc-CATH can kill a variety of common aquatic pathogens, regulate the immune function of largemouth bass, improve the resistance of largemouth bass to bacterial infections, and improve the survival rate of the largemouth bass. The Hc-CATH has wide application prospects in the field of aquaculture.
Owner:SUZHOU UNIV
Application of natural host defense peptide alligatorin5
ActiveCN107261113BEnhance immune functionImprove survival rateAntibacterial agentsPeptide/protein ingredientsImmunityMicrobiology
The invention relates to application of natural host defense peptide Alligatorin5 to preparation of aquatic pathogenic bacterium resisting medicine. The invention also discloses application of the natural host defense peptide Alligatorin5 to preparation of an aquaculture animal immune activating agent. The invention further discloses application of the natural host defense peptide Alligatorin5 to preparation of aquaculture animal feed. The results of study using hairy crabs as experimental animals show that the Alligatorin5 can enhance the immune function of the hairy crabs; the immunity of the hairy crabs on bacterial infection is improved; the survival rate of the hairy crabs is improved. The Alligatorin5 has wide application prospects in the field of aquaculture.
Owner:中科肽谷(山东)生命科学研究有限公司
A non-migration antibacterial cellulose-based foam and its preparation method
The invention discloses migration-free antibacterial cellulose-based foam. The migration-free antibacterial cellulose-based foam is prepared from the following raw materials in parts by weight: 95 to 99 parts of water, 1 to 5 parts of cellulose, 0.1 to 0.3 part of a wet strengthening agent, 0.1 to 0.5 part of a surfactant, 0.01 to 0.2 part of a cross-linking agent and 0.03 to 0.2 part of an antibacterial agent. A migration-free antibacterial cellulose-based foam product is prepared through the following steps: mixing the weighed cellulose and water and defibering; (2) adding the wet strengthening agent, the surfactant, the cross-linking agent and the antibacterial agent, which are weighed in step (1), into a substance obtained by defibering; mixing and stirring, and filtering; drying for 8h to 48h at temperature in a range from room temperature to 60 DEG C. A preparation process of the migration-free antibacterial cellulose-based foam is simple and environmentally friendly; extra equipment is not needed and the product can be produced by a standard papermaking basic facility, so that the preparation process is suitable for industrial production.
Owner:GUANGXI UNIV
Antibacterial peptide MS-CATH from Miniopterus fuliginosus and application thereof
ActiveCN113480630ABroad-spectrum high-efficiency antibacterial effectImprove antibacterial propertiesAntibacterial agentsCosmetic preparationsVeterinary DrugsAntibacterial activity
The invention discloses an antibacterial peptide MS-CATH from Miniopterus fuliginosus and an application thereof in the antibacterial aspect. The antibacterial peptide MS-CATH disclosed by the invention is derived from the Miniopterus fuliginosus. A mature peptide sequence of the antibacterial peptide is obtained by searching a gene database of the Miniopterus fuliginosus and screening and analyzing, and the amino acid sequence of the antibacterial peptide is shown as SEQ ID NO.1 in a sequence table. Through contrastive analysis, the natural antibacterial peptide MS-CATH is obviously different from the amino acid sequences of all known antibacterial peptides at present, and belongs to a novel antibacterial peptide. An antibacterial experiment result shows that the antibacterial peptide MS-CATH disclosed by the invention has extremely strong antibacterial activity on gram-positive bacteria, gram-negative bacteria and fungi, is rapid in bactericidal effect, has the characteristic of low hemolytic activity, and can be applied to preparation of drugs for resisting bacteria and inhibiting bacterial growth, preservatives, veterinary drugs, animal feeds and cosmetics.
Owner:GUIZHOU NORMAL UNIVERSITY
Application of natural host defense peptide alligatorin4
ActiveCN107252475BEnhance immune functionImprove survival rateAntibacterial agentsPeptide/protein ingredientsZoologyAquaculture
Owner:思格(苏州)生物科技有限公司
A kind of nano polymer antibacterial agent and preparation method thereof
InactiveCN103694401BStrong electrostatic effectStrong captureBiocideAntifouling/underwater paintsMicroorganismNanotechnology Techniques
The invention discloses a nanometer polymer antibacterial agent and a preparation method thereof. The invention utilizes the organic nanotechnology of emulsion polymerization to directly obtain the nanometer macromolecule product with antibacterial function through a one-step process. The particle size of the obtained product is in the range of 40-90nm, with large specific surface area and high utilization rate. At the same time, the surface of the antibacterial agent is positively charged, which can firmly capture and absorb harmful microorganisms and interfere with their physiological processes; The puncture damage will cause its death, realize the broad-spectrum and high-efficiency antibacterial effect, and have the characteristics of contact sterilization. In addition, the product of the invention has a stable structure, is not easy to migrate, is easy to disperse, has good compatibility with polymer materials, has a wide range of applications, and is low in cost.
Owner:SOUTH CHINA AGRI UNIV
A reptile antimicrobial peptide alligatorin5 and its application
ActiveCN104163861BBroad-spectrum high-efficiency antibacterial effectSmall molecular weightAntibacterial agentsCosmetic preparationsChinese alligatorAntibacterial activity
The invention discloses a reptile-derived antibacterial peptide Alligatorin5, an amino acid sequence thereof and applications of the antibacterial peptide in the antibacterial field. The antibacterial peptide Alligatorin5 is derived from Chinese alligator. By searching a Chinese alligator gene database, screening and analyzing, a mature peptide sequence of the antibacterial peptide is obtained. The amino acid sequence of the antibacterial peptide Alligatorin5 is shown as SEQ ID NO.1 in a sequence table. By comparative analysis, the antibacterial peptide Alligatorin5 is obviously different from amino acid sequences of antibacterial peptides known at present, and belongs to a novel antibacterial pepetide. Antibacterial experiments show that: the antibacterial peptide Alligatorin5 has high antibacterial activity for gram positive bacteria, gram negative bacteria and funguses, and is broad in antibacterial spectrum and efficient; the antibacterial peptide Alligatorin5 has characteristics of low hemolytic activity, salt tolerance, heat tolerance, good thermal stability, and the like, and can be used for the fields of medicines, cosmetics, food fresh-keeping and the breeding industry.
Owner:SUZHOU UNIV
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