38results about How to "Normal food intake" patented technology

The invention relates to a compound medicament for treating diabetes and nephrosis and process for preparation, wherein the raw materials include Chinese medicinal herbs of astragalus root, dried rehmannia root, selfheal, zedoary, winged euony twigs and right amount of starch gum.

The invention discloses a method for constructing an ovarian cancer transplantation tumor model based on an organoid method, and belongs to the field of medicines. According to the invention, an "organoid" culture technology is adopted, and a micro-carrier is used as a support material for culturing a patient-derived ovarian cancer cell-3D material complex; then the cell-3D material complex is directly inoculated under the skin of a normal immune mouse, and a patient-derived ovarian cancer transplantation tumor model is constructed, so that a problem that immune-deficiency mice such as severecombined immunodeficiency (SCID) mice, nude mice and the like are adopted in existing human ovarian cancer transplantation tumor models, the price is high, breeding is difficult, the tumor forming rate is low and the like can be solved, especially a problem that the existing immune-deficiency mouse human ovarian cancer transplantation tumor model cannot reflect impotent effects of an organism immune system in occurrence and development processes of tumors is solved, and a problem that an immune-deficiency mouse human transplantation tumor model is long in tumor forming period and cannot meet drug allergy requirements of patients urgently needing clinic drug therapy is solved. The method is applied to the field of mouse model construction.

The invention discloses a method for constructing a tumor xenograft model in mice immunized with gastric cancer based on an organ-like method, and an application thereof. The invention relates to a medical tumor animal model, based on an organ-like method. For the first time, the present invention employs a quasi-organ technique, that is, using a microcarrier as substrate. The composite human gastric cancer cell line SGC-7901/MKN-45 is transplanted subcutaneously into C57BL/6 mice to establish a tumor model of human gastric cancer with normal immune function. The tumor model constructed by this method has good tumorigenicity, and the tumorigenicity rate is up to 75%. The HE staining and the immunohistochemistry of the transplanted tumor accord with the characteristics of human gastric cancer. Compared with the existing immunodeficient mice transplanted tumor model, the model can better study and further clarify the mechanism of tumor occurrence and development in the normal immune system, and also provides a more valuable new animal model for the research and development of anticancer drugs. The invention is applied to the tumor model field.

The invention relates to a preparation for preventing lateolabrax japonicus enteritis and also relates to a preparation method of the preparation for preventing the lateolabrax japonicus enteritis. The preparation for preventing the lateolabrax japonicus enteritis is prepared from the following components in parts by mass: 27 to 35 parts of pomegranate barks, 22 to 26 parts of fresh hydrocotyle sibthorpioides juice, 21 to 26 parts of hibiscus barks, 21 to 25 parts of Rodgersia pinnata Franch., 20 to 25 parts of creeping oxalis, 19 to 23 parts of dandelions, 18 to 24 parts of aconitum gymnandrum maxim, 17 to 23 parts of houttuynia cordata, 17 to 22 parts of cocklebur fruits, 15 to 23 parts of hawthorn fruits, 14 to 20 parts of peruvian groundcherry herb, 14 to 20 parts of common cnidium fruits, 14 to 20 parts of lotus seeds, 13 to 19 parts of roots of Szechwan raspberry, 12 to 18 parts of Myositis sylvatica, 12 to 18 parts of Chinese galls, 10 to 18 parts of lophatherum gracile, 11 to 17 parts of resurrection lily rhizomes, 10 to 16 parts of blackberry lily and the like. The preparation for preventing the lateolabrax japonicus enteritis, provided by the invention, has a good treatment effect on the lateolabrax japonicus enteritis.

The invention belongs to the technical field of aquaculture, and relates to a feed additive for preventing and treating bacterial gill-rot disease of ictalurus punctatus and a preparation method of the feed additive for preventing and treating the bacterial gill-rot disease of the ictalurus punctatus. The feed additive for preventing and treating the bacterial gill-rot disease of the ictalurus punctatus is prepared from the following components in parts by mass: 35 to 45 parts of ginger juice, 26 to 32 parts of lalang grass rhizome, 26 to 32 parts of cactus juice, 25 to 33 parts of acorus calamus, 25 to 32 parts of onion juice, 22 to 30 parts of portulaca oleracea, 22 to 28 parts of dark plum, 22 to 28 parts of dried orange peel, 20 to 28 parts of Chinese gallnut, 18 to 28 parts of almond powder, 16 to 26 parts of euphorbia helioscopia, 16 to 26 parts of acanthaceae sericocalyx chinensis, 10 to 18 parts of fish oil and the like. According to the feed additive and the preparation method disclosed by the invention, the occurrence of the bacterial gill-rot disease of the ictalurus punctatus can be effectively prevented; in addition, the bacterial gill-rot disease of the ictalurus punctatus can be effectively treated.

The invention belongs to the field of medicine, and relates to a method for constructing a patient-derived tumor xenograft model in mice immunized with hepatocellular carcinoma based on an organ-likemethod, and an application thereof. The aim of the invention is to use the organ-like culture technology, adopts microcarrier as scaffold material, and combines the liver cancer cells from patient toculture the cells. The invention also discloses an organ-like method for preparing the liver cancer cells-3D material complex, and then directly into that cell-3D material complex is inoculated subcutaneously into normal immunized mice to construct liver cancer transplanted tumor model from patients in vivo, which solved the problems of using nude mice, SCID mice and other immunodeficient mice, which are difficult to feed, expensive and lower tumor formation rate. Especially, it can solve the problem that human hepatocellular carcinoma transplanted tumor model in immunodeficiency mice can notreflect the important role of immune system in tumor occurrence and development, and human tumor transplanted tumor model in immunodeficiency mice has a long tumor formation cycle, which urgently needs the drug-sensitive demand of patients with clinical urgent need. The invention is applied to the field of mouse model construction.

The invention discloses a traditional Chinese medicine for dermatosis treatment; the invention is prepared with the following raw medicines by weight portion: zanthoxyli of 8 to 12 portions, gynocardia of 9 to 15 portions, fructuskochiae of 12 to 18 portions, sulfur of 5 to 9 portions, xanthium of 16 to 24 portions, apiary of 12 to 18 portions, osthol of 9 to 15 portions, alum of 12 to 18 portions, densefruit pittany root-bark of 16 to 24 portions. The invention has the advantages of good efficacy, high efficiency, no side effect on human body, and no relapse after cure.

The invention belongs to the technical field of aquaculture, and relates to a feed additive for preventing white-spot disease of parrot fishes. The invention also relates to a preparation method of the feed additive for preventing the white-spot disease of the parrot fishes. The feed additive for preventing the white-spot disease of the parrot fishes comprises the following components in parts by weight: 36-42 parts of calamus, 30-35 parts of sweet potatoes, 28-35 parts of Chinese honey locust, 28-34 parts of honeysuckle, 28-34 parts of peach leaves, 27-34 parts of garden burnet roots, 25-33 parts of lavender, 24-32 parts of sculellaria barbata, 24-30 parts of schisandra chinensis, 21-27 parts of capillary wormwood herb, 21-27 parts of patrinia scabiosaefolia, 20-26 parts of rush juncus effusus roots, 19-27 parts of Lip-fern, 19-25 parts of acacia catechu, 14-21 parts of garlic and 12-20 parts of hedyotis diffusa. With the adoption of the feed additive disclosed in the invention, the white-spot disease of the parrot fishes can be effectively prevented and treated.

The invention discloses a traditional Chinese medicine for treating tinea of feet and hands as well as eczema, which is prepared from 5-25 parts by weight of radix sophorae flavescentis, 5-15 parts by weight of radix stemonae, 5-15 parts by weight of sedum sarmentosum, 2-20 parts by weight of felwort, 5-15 parts by weight of chaulmoogra, 5-15 parts by weight of golden cypress, 3-15 parts by weight of alum, 5-15 parts by weight of Chinese honeylocust fruit, 5-15 parts by weight of pepper, 5-15 parts by weight of rhizoma smilacis glabrae, 3-30 parts by weight of fructus cnidii, 5-15 parts by weight of agastache rugosus, 5-15 parts by weight of cortex pseudolaricis, 5-15 parts by weight of pericarpium zanthoxyli, 1-10 parts by weight of borneol, 5-15 parts by weight of saururus chinensis, 5-15 parts by weight of solanum lyratum, 5-20 parts by weight of cyrtomium fortunei and 5-25 parts by weight of yam rhizome. The traditional Chinese medicine is prepared according to the traditional Chinese medicine theory, is scientific in component collocation, and has the characteristics of clearing heat and expelling damp as well as killing parasites to relieve itching, and the components are supplement each other.

The invention discloses a traditional Chinese medicine composition for treating infantile asthma. The traditional Chinese medicine composition comprises the following raw materials: ginseng, geckos, turtle shell in vinegar, snakegourd seeds, radix stemonae, pseudo-ginseng, walnut kernels, ginger, deer-horn glue, endothelium corneum gigeriae galli, dried orange peels, cassia twig, liquorice, cocklebur fruit, Sichuan fritillary bulb powder and medlar. The traditional Chinese medicine composition is prepared by mixing the finely selected raw materials through multi-time clinical verifications, and is a good recipe capable of strengthening healthy energy and eliminating evil; the traditional Chinese medicine composition is based on a principle of treatment of both symptoms and root causes, is capable of tonifying the kidney and vital energy and removing stasis, and has remarkable effects of relieving asthma, preventing a cough and reducing phlegm; after the traditional Chinese medicine composition is taken, the effect is quickly brought into play; by regulating the functions of internal organs, tonifying the kidney, absorbing vital energy, clearing heat and moistening the lung to balance yin and yang as well as five internal organs, the body resistance is enhanced, the lung microcirculation is improved, the symptoms such as fatigue, easy sweating, throat itching, dry cough, excessive phlegm and anorexia are eliminated, the repeated attack of the asthma is removed, and the purpose of radically treating the infantile asthma is achieved.

The invention relates to a method for improving water quality of a drinking water source. The method comprises the following steps: (1) removing bottom sludge of a target water; (2) determining a total water volume of the target water as well as a nitrogen content, a phosphorus content and a content of chlorophyll a in the water; (3) dispensing daces, chubs, bighead carps, crucians and weevers into the target water in a ratio of (45 to 55): (25 to 31): (15 to 20): (2 to 5): (1 to 2) according to the total water volume, the nitrogen content, the phosphorus content and the content of the chlorophyll a; (4) and fishing after the daces are dispensed for 8 to 12 months. The water quality of the drinking water source is improved by removing the bottom sludge in combination with the increment of aquatic animal fishes in the water, the algae in the water is reduced, the harm of tap water on the human body can be alleviated, and the disease occurrence probability caused by the water can be reduced; and the advantage of the bottom sludge removal of the water is to remove the phosphorus and heavy metals deposited in the bottom sludge; and on the other aspect, the content of the phosphorus of the water can be controlled.

The invention discloses a traditional Chinese medicament for treating epilepsy. The traditional Chinese medicament is prepared from the following components in parts by weight: 10-30 parts of cornu cervi, 10-30 parts of tortoise shell, 10-30 parts of turtle shell, 10-30 parts of pig hoof, 10-30 parts of buffalo horn, 10-30 parts of cornu gorais, 10-30 parts of snakegourd seed, 10-30 parts of ochre, 10-30 parts of arisaema cum bile, 10-20 parts of pinellia ternata, 10-20 parts of tabasheer, 10-20 parts of alum, 2-10 centipedes, 10-20 parts of irkutsk anemone rhizome, 2-10 parts of chlorite schist and 2-20 parts of coptis chinensis. The traditional Chinese medicament is prepared according to traditional Chinese medical administration theory, and has the characteristics of scientific compatibility, resuscitation induction and phlegm-sweeping and wind-extinguishing and supplements each other.

The invention discloses a traditional Chinese medicine for treating post-traumatic brain syndrome. The traditional Chinese medicine is prepared from 8-18 parts of rehmannia glutinosa, 3-6 parts of deer-horn glue, 8-18 parts of angelica sinensis, 5-15 parts of dried body of ground beetle, 6-10 parts of arisaema cum bile, 6-15 parts of peach kernel, 6-15 parts of flowers carthami, 5-10 parts of ligusticum wallichii, 6-12 parts of root of common peony, 6-12 parts of radix bupleuri, 5-10 parts of platycodon grandiflorum, 6-15 parts of radix achyranthis bidentatae, 5-10 parts of fructus aurantii, and 6-12 parts of thyme. The traditional Chinese medicine has the characteristics of scientific collocation according to the traditional medicine theory in traditional Chinese medical science, supplements with each other, strengthens the brain, and promotes blood circulation to remove blood stasis.

The invention belongs to the field of medicine and successfully introduces a patient-derived lymphoma immunodeficient mouse xenograft model into lymphoma drug research and development and in-vivo drugsensitive tests on related drugs. Compared with tumor in-vitro drug sensitive tests and traditional mouse xengraft models, the constructed patient-derived lymphoma immunodeficient mouse xenograft model can better research and further elaborate occurrence and development mechanisms of tumor, and meanwhile, a more valuable new animal model is provided for research and development of anticancer drugs. The construction method is applied to the field of construction of mouse models.

The invention discloses a traditional Chinese medicine composition for treating infantile enuresis. In the traditional Chinese medicine, the infantile enuresis is categorized as insufficiency of natural endowmen and caused by deficiency-caused cold, deficiency of spleen qi, disorder of water lane, excessive vesica urinaria restriction and urinary bladder opening-closing disorder. In order to solve the problems, the traditional Chinese medicines, which have the effects of strengthening the spleen and replenishing qi, tonifying and reinforcing the kidney and tranquilizing by nourishing the heart, are selected to be decocted with water to obtain decoction, wherein the medicines are as follows: spleenwort, human placentae, white atractylodes rhizome, American ginseng, semen biotae shelled, poria with hostwood, semen alli tuberose, gordon euryale seed, mantis egg-case, divaricate knotweed root, common fennel, faenum graecum and Chinese yam. According to the clinical test of preparation department, the total effective rate is 96.0% which is remarkably better than that of the control group. In particular, the treatment by Chinese herbs is not only good in treatment effect, but also stable in effect and free of recurrence after the treatment.

The invention belongs to the technical field of aquiculture, relates to a feed additive for preventing and treating fester disease of Epinephelus akaara, and further relates to a preparation method of the feed additive for treating the fester disease of Epinephelus akaara. The feed additive comprises the following components in parts by mass: 36-44 parts of onion juice, 27-33 parts of a garden burnet infusion, 24-30 parts of gallnut, 24-30 parts of honeysuckle, 23-31 parts of phaseolus calcaratus, 23-31 parts of red bean, 21-29 parts of herba houttuyniae, 21-28 parts of radix arnebiae, 20-26 parts of mentha arvensis, 19-27 parts of oroxylum indicum, 17-25 parts of coriander, 17-24 parts of polygonum orientale, 16-24 parts of reed rhizome, 15-23 parts of milk vetch, 13-23 parts of euphorbia helioscopia, 13-20 parts of cicada ecdysis and the like. The feed additive can effectively prevent and treat the fester disease of Epinephelus akaara.

The invention discloses a powdery formulated feed for anguilla marmorata overwintering, wherein a technical process for the same comprises the following step of: preparing the powdery formulated feed for anguilla marmorata overwintering from various raw material constituents according to a powdery feed processing method. The powdery formulated feed for anguilla marmorata overwintering comprises the raw material constituents in percentage by weight: fish meal, alpha-starch, extruded soybean, oligopeptide soybean meal, beer yeast, mineral substances, finishing multi-vitamins, choline chloride, monocalcium phosphate and the like. Compared with other feeds, the powdery formulated feed for anguilla marmorata overwintering disclosed by the invention is remarkably increased in the contents of oligopeptides and plant proteins, and obviously reduced in the dosage of fish meal; via the addition of the plant proteins, the cost of the feed is decreased, and the feed is more comprehensive in nutrition; meanwhile, via the addition of the oligopeptides and the proteins, feeding attraction property and body disease resistance can be further improved. By using the powdery formulated feed for anguilla marmorata overwintering disclosed by the invention, the nutrition state of an anguilla marmorata overwintering group can be greatly improved, the digestive utilization of the feed can be promoted, and the body immunity of anguilla marmorata can be enhanced.

The invention belongs to the technical field of aquaculture, relates to a compound preparation for preventing and treating white-spot disease in parrotfish, and also relates to a preparation method of the compound preparation for preventing and treating white-spot disease in parrotfish. The compound preparation for preventing and treating white-spot disease in parrotfish consists of the following components in parts by mass: 36-42 parts of acorus calamus, 30-35 parts of sweet potato, 28-35 parts of gleditsia sinensis, 28-34 parts of honeysuckle, 28-34 parts of peach leaf, 27-34 parts of sanguisorba officinalis, 25-33 parts of lavender, 24-32 parts of herba scutellariae barbatae, 24-30 parts of fruit of Chinese magnoliavine, 21-27 parts of oriental wormwood, 21-27 parts of herba patriniae, 20-26 parts of juncus root, 19-27 parts of lip-fern, 19-25 parts of acacia catechu, 14-21 parts of garlic, 12-20 parts of oldenlandia diffusa and the like. The compound preparation disclosed by the invention can be used for effectively preventing and treating the occurrence of the white-spot disease in parrotfish.

The invention belongs to the technical field of aquiculture, relates to a compound preparation for preventing and treating channel catfish ichthyophthiriasis, and also relates to a preparation method of the compound preparation for preventing and treating channel catfish ichthyophthiriasis. The compound preparation for preventing and treating channel catfish ichthyophthiriasis is prepared from the following components in parts by weight: 38-44 parts of torilis japonica, 30-35 parts of euphorbia helioscopia, 30-35 parts of calamus, 30-35 parts of polygonum orientale, 30-35 parts of houttuynia, 27-33 parts of courled mallow, 26-32 parts of Chinese milk vetch, 26-32 parts of dandelion, 25-32 parts of cnidium fruit, 24-30 parts of purslane, 22-28 parts of sagebrush, 18-26 parts of cocklebur fruit, 18-26 parts of wrinkled gianthyssop, 17-24 parts of honeysuckle and the like. The raw material components of the compound preparation are green and purely natural, and the compound preparation is capable of effectively preventing and treating channel catfish ichthyophthiriasis.