338 results about "Ageing skin" patented technology

This invention relates to in-situ preparation of the derivatives of various hydroxy acids (HA), such as alpha-(Alpha) Hydroxy Acids (AHA), beta-(Beta) Hydroxy Acids (BHA), and Poly-Hydroxy Acids (PHA) with certain skin beneficial organic hetero-atom bases and their application in skin resurfacing (exfoliation), and in the synergistic treatment and regulation of topical disorders of skin such as skin aging, wrinkles, acne, rosacea, age-spots, canker sores, striae distensae (stretch marks), pimples, skin redness, and dry skin conditions of cracking, flaking, and scaling. Most HA derivatives produced by the in-situ method do not cause skin irritation and skin redness effects that are commonly experienced with AHA and BHA, yet there is no loss of their skin beneficial effects. These compositions can be traditional water and oil emulsions, liposomes, suspensions, colloids, solutions, masks, muds, serums, sprays, gels, lotions, creams, cleansers, and anhydrous systems, thus offering a wide choice of formulations to meet their consumer appeal and acceptance requirements.

The present invention relates to the use of one or more tripeptides selected from the group consisting of ^NLys-Pro-Val^C, ^NLys-Pro-Thr^C and ^NpGLu-His-Pro^C for the reduction of oxidative stress. The above tripeptides are particularly useful for the treatment of a disease or damage caused by oxidative stress; such as vitiligo, scleroderma, necrosis, or erythema; furthermore, a disease or damage of the hair, like premature hair loss or premature formation of grey hair. Furthermore the invention relates the cosmetic use of the above tripeptides, in particular against skin aging. Further the invention relates cosmetic compositions containing at least one of said tripeptides.

The present invention refers to surgery threads which are flexible, made of resistant inert plastic material and being employed in aesthetic surgeries in the cases of skin ageing prevention and/or correction surgeries for motion injury signals, wherein the threads comprise a previous defined sequence of a tissue support arrangement having a number of fixing claws placed alongside of the thread surface and wherein an arrangement of an upstream claw (1) set and a downstream claw (2) set is provided.

The invention discloses an external skin care product capable of adjusting skin immunity and delaying skin aging. The external skin care product is characterized by comprising powder, an aqueous solution and emulsion, wherein the powder comprises oligopeptide-1 and ginsenoside; the aqueous solution comprises glycyrrhiza glabra root extract, artemisia capillaris flower extract, mulberry root extract, jujube fruit extract, scutellaria root extract, hydrolyzed rice protein and nicotinamide; and the emulsion comprises hgytantriol bifida ferment lysate, creatine, carnosine, alpha glucosyl hesperidin, hexapeptide-3, centella asiatica extract, coenzyme Q10 inclusion complex, opuntia ficus-indica stem extract, rhodiola rosea extract, saussurea involucrate extract, pseudo-ginseng root extract and Chinese angelica extract inclusion complex. According to the external skin care product, the powder, the aqueous solution and the emulsion are jointly used, and the external skin care product can reduce wrinkle and pachulosis, even skin tone and improve skin elasticity and skin firmness, so that the skin is finer and smoother and looks young.

The invention discloses a multi-effect skin caring and smoothening traditional Chinese medicine lotion which is characterized by comprising, by weight, 35-45 parts of lightyellow sophora root, 35-45 parts of common cnidium fruit, 28-33 parts of Chinese gall, 35-45 parts of baical skullcap root, 18-22 parts of cattail pollen, 75-85 parts of ganoderma lucidum, 110-130 parts of cortex mori, 35-45 parts of milkvetch root, 35-45 parts of radix rehmanniae, 35-45 parts of oat, and glycerin which is 0.5-0.56 times of the aforementioned materials by weight, with the balance being clean water for extraction. The multi-effect skin caring and smoothening traditional Chinese medicine lotion made from natural and environment-friendly materials has stable and reliable effect and wide application range, especially has good effects in removing freckle, wrinkle and acne, whitening, moisturizing and healing skin injury, and can not only be used to delay aging of skin and repair injury to skin caused by some hormone drugs and cosmetics but also reduce and even remove face splash, acne and wrinkle to make skin smooth, bright and elastic.

The invention belongs to the field of cosmetics, and particularly relates to a composition containing bifida ferment lysate and a preparation method and application of the composition to the cosmetics. The composition includes a bifida ferment lysate composition, a peptide composition and a rice extract, and the composition is prepared from the following components in parts by mass: 1-40 parts ofthe bifida ferment lysate, 1-20 parts of the peptide composition, and 1-20 parts of the rice extract, and the composition further includes 1-20 parts of a moisturizing composition, and the bifida ferment lysate composition includes bifida freeze-dried powder, and a bifida freeze-dried powder lyase solution. The composition containing the bifida ferment lysate has the beneficial effects that a formula is reasonably set, functions are various, wrinkles can be significantly reduced, the pigment content is reduced, skin glossiness is increased, the skin color is brightened, skin elasticity is increased, the skin barrier is repaired, the water loss is reduced, the composition has no stimulation to the skin, and at the same time, the composition has the functions of preventing skin aging and keeping moisture for a long time, and makes the skin obtain a healthy and natural bright white state.

The invention belongs to the technical field of cosmetics and particularly relates to a spray agent containing wormwood hydrolat and a preparation method thereof. The spray agent containing wormwood hydrolat is mainly prepared from the wormwood hydrolat, rose hydrolat, chamomile extract, trehalose, allantoin, dipotassium glycyrrhizinate, hyaluronic acid, glycerinum, preservative and water. The spray agent containing the wormwood hydrolat has the functions of sterilization property, antianaphylaxis and antiphlogosis and itching relieving of broad spectrum and meanwhile has the effects of slowing down skin aging, promoting blood circulation of skin, supplementing water, moisturizing, refreshing and restoring consciousness. The spray agent containing wormwood hydrolat is free of stimulation to skin, the phenomenon of skin poisoning can be avoided after the spray agent is used for a long time, and the spray agent is suitable for being used for various people, especially suitable for being used by people with sensitive skin.

The invention discloses an Rg2 group and an Rh1 group of red ginseng saponin and a preparation method as well as applications in preparing cosmetics preventing skin aging. Extracts which are extracted from ginseng roots, do not contain saponin, and contain saponin enzyme of ginseng and other water-soluble matters react with ginsenoside Re to obtain red ginseng mixed saponin Rg2 group consisting of red ginseng rare saponin 20(S)-Rg2, 20(R)-Rg2, Rg4 and Rg6, and the extracts react with ginsenoside Rg1 to obtain the red ginseng mixed saponin Rh1 group consisting of red ginseng rare saponin 20(S)-Rh1, 20(R)-Rh1, Rh4 and Rk3. Compared with a saponin Rg2 monomer and a saponin Rh1 monomer, the function of the Rg2 group and Rh1 group of red ginseng mixed saponin for promoting skin fibroblast collagen synthesis is improved obviously, the Rg2 group and Rh1 group of red ginseng mixed saponin are more safe to skin and human bodies, and have less side effects.

Compounds of structural formula (I) are disclosed as useful for modulating the androgen receptor (AR) in a tissue selective manner in a patient in need of such modulation, and in particular for antagonizing AR in the prostate of a male patient or in the uterus of a female patient and agonizing AR in bone and/or muscle tissue. These compounds are useful in the treating conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including: osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, female sexual dysfunction, post-menopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, aplastic anemia and other hematopoietic disorders, pancreatic cancer, renal cancer, prostate cancer, arthritis and joint repair, alone or in combination with other active agents. In addition, these compounds are useful as pharmaceutical composition ingredients alone and in combination with other active agents.

Compositions are provided that include date palm pollen or an extract thereof. The compositions may be formulated for topical use in methods of treatment or prophylaxis of various skin conditions or methods to counteract the effects of skin aging.

The present invention provides a skin external-use agentia combination which contains more than one of a lotus extract and a dark plum extract serving as effective components and has an antioxidant activity. The skin external-use agentia combination of the present invention has an excellent antioxidant effect, and can be applied to cosmetic material combinations or pharmic combinations. In addition, the skin external-use agentia combination of the present invention also can effectively prevent erythema, improve colour of the skin, and prevent skin from aging.

The invention belongs to the technical field of cosmetics and particularly discloses a skin care matrix with moisture preserving and oxidation resisting effects. The skin care matrix is prepared from the following components in parts by weight: 25-30 parts of apple fruit extracts, 20-25 parts of sodium carboxymethyl glucan, 2-3 parts of oligomeric sodium hyaluronate, 6-10 parts of water-soluble fullerene, 15-20 parts of colloidal platinum and 12-32 parts of water. By rational combination of effective substances and optimization of the dosage of the substances, the four active effective substances are complementary, can be degraded and completely absorbed by skin, provide nutrients for the skin and have long-lasting moisture preserving and oxidation resisting effects. The prepared skin care matrix can be added to cream, milk lotions, lotions and other cosmetics and can improve the moisture preserving and oxidation resisting effects of the cosmetics, so that the skin is moisturized and whippy, and aging of the skin is prevented.

The invention belongs to the field of use of a stem cell conditioned medium in medicinal cosmetics, and especially relates to an application of the conditioned medium in skin ageing resistance. Researches find that a large amount of complex active substances secreted by stem cells are stored in a medium in the in vivo culture process of mesenchymal stem cells, and is called as the stem cell conditioned medium, and an obtaining method of the medium comprises the following steps: carrying out digestive passage on p2 generation mesenchymal stem cells by using 0.05% pancreatin, inoculating 2*10<6> into a 150mm culture dish, and culturing to obtain p3 generation cells; and sucking the obtained culture supernatant when 80% of the p3 generation cells fuse, washing by using PBS twice, adding a new serum-free medium, putting the obtained cells in a 37DEG C 5% CO2 incubator, culturing for 48h, and collecting the obtained culture supernatant to obtain the stem cell conditioned medium. The stem cell conditioned medium obtained in the invention can supplement skin cell metabolism promotion substances lacked in skins and also can induce new collagen synthesis in order to maintain elasticity of skins and reduce wrinkles.

The invention provides an anti-aging compound, an anti-aging cosmetic and a preparation method thereof. According to the anti-aging compound, plantain herb seed extract, lupine extract and lotus extract are compounded, so that skin aging can be effectively prevented and improved, skins can be tightened, and a skin anti-aging function is achieved. Besides, according to the anti-aging cosmetic, the anti-aging compound serves as an active component, other raw materials serve as auxiliary materials to prepare anti-aging skin lotion, anti-aging emulsion and anti-aging cream, so that use requirements of different people in different places can be met while skin aging can be effectively resisted. According to the method, the components serve as raw materials, the raw materials are mixed and emulsified to prepare corresponding anti-aging cosmetics, and the preparation method has the advantages of convenience, fine effect of the prepared anti-aging cosmetic and the like.

The invention relates to a composition containing umbilical cord mesenchymal stem cell exosomes. The composition comprises the following components in percentage by mass: 0.02-0.6% of the umbilical cord mesenchymal stem cell exosomes, 2.5-5.0% of an antioxidant, 1.5-2.5% of algal polysaccharides, 5.6-12.5% of a humectant, 0.05-0.6% of nicotinamide, 0.2-0.8% of hydroxyethyl cellulose, 0.1-0.5% of ceramide-2,, and the balance of deionized water. According to the composition, on the basis of adding the umbilical cord mesenchymal stem cell exosomes, the humectant, the antioxidant and the algal polysaccharides are matched, so that metabolism of skin cells can be accelerated, oxidation resistance and regeneration capacity of basal cells can be recovered, skin aging can be prevented, skin elasticity and plumpness can be increased, pores can be shrunk, and gloss can be improved.

Disclosed is a cosmetic or dermatological preparation which comprises one or more extracts of Saxifraga oppositifolia (purple saxifrage) and/or one or more extracts of Soldanella alpina (alpine snowbell). The use of these extracts to combat extrinsic and intrinsic skin aging is likewise described.

The invention discloses a traditional Chinese medicine composition for beautifying skin. The effective components of the composition consists of the following raw medicines in daily dosage: 2 to 8 grams of ginseng, 3 to 6 grams of angelica, 3 to 9 grams of red sage roots, 100 to 700 milligrams of forest frog oviducts and 145 to 900 milligrams of grape seed extract. The medicine composition can be added with microcrystalline cellulose or magnesium stearate as auxiliary materials to prepare tablets, or be added with stearic acid, glyceryl monostearate, hydrogenerated polyisobutene, olive oil, methyl glucose sesquistearate, glycerin, azone, ethyl nipagin ester and distilled water as the auxiliary materials to prepare cream. The composition has the advantages of high product safety performance, no toxic or side effect, speckle removal, wrinkling resistance, skin aging improvement, good skin beautifying efficacies, and stable and reliable product quality. In addition, the composition is rich in resources of the raw medicines, scientific and reasonable in formulation and simple in preparation process, and meets the requirements of industrial production.

The invention specifically discloses a composite anti-ageing skin-care composition and a manufacturing method. The composite anti-ageing skin-care composition comprises the following raw materials by weight: 0.05 to 10 parts of traditional Chinese medicine active site extract, 0.05 to 5 parts of polypeptide composition, 0.02 to 3 parts of diguanosine tetraphosphate and 82 to 99.88 parts of deionized water. The traditional Chinese medicine active site extract comprises the following raw materials by weight: 10 to 40 parts of lanatechead saussurea herb with flower, 2 to 30 parts of Chinese angelica, 5 to 25 parts of tuber of dwarf lilyturf and 5 to 30 parts of honeysuckle flower; and the polypeptide composition is a composition of two or more selected from the group consisting of tripeptide, tetrapeptide, pentapeptide, hexapeptide and nonapeptide. Since a plurality of traditional Chinese medicinal active components are added into anti-ageing active matters of the composite anti-ageing skin-care composition, the composite anti-ageing skin-care composition is capable of nourishing and moisturizing the skin, rectifying qi and blood, nourishing yin, moisturizing dryness, clearing away heat and toxic matters, highly efficiently removing oxyradical, inhibiting activity of tyrosinase and controlling melanin generation, has powerful anti-ageing, skin-care and skin-tenderizing effects and is free of toxicity and harm. When added into a cosmetic, the composition exerts substantial anti-ageing effect.

The invention discloses whitening and moisturizing essence containing natural ingredient extract and a preparation method of the essence. The essence contains grape seed oil, wheat germ oil, rose hip oil, hazelnut oil, aloe oil, self-emulsifying compound emulsifier AC-402, all-around cold-prepared emulsifier G57, distilled water, Rhodiola rosea water extract, Centella water extract, loofah water extract, cherry juice, silk protein powder, vitamin C, royal jelly, glycerin, ethylparaben and 75% alcohol. The essence does not contain any hormone and harmful chemical substance, and is free of damage to and irritation of skin and mild and non-irritant if being provided with face. In addition, natural traditional Chinese medicine and plant oil which are rich in various skin nutrients are selected for a facial mask, shedding of dead skin is promoted, and melanin precipitation is prevented; growth and metabolism of tissue cells are promoted, water locking of skin and repair of sunburn skin are promoted, and skin aging is delayed while fine wrinkles can be weakened.

The invention discloses a composition capable of improving skin pores and achieving long lasting moisture retention effect, and applications thereof. The composition capable of improving skin pores and achieving long lasting moisture retention effect comprises, by mass, 5 to 15 parts of fomitopsis officinalis extract product, 5 to 15 parts of ADS-Oligonol, 2 to 8 parts of honey extract product, and 2 to 8 parts of ceratonia siliqua seed extract product. The fomitopsis officinalis extract product, ADS-Oligonol, the honey extract product, and the ceratonia siliqua seed extract product are adopted to prepare the composition, synergistic interaction effect is achieved, skin pore area improving rate is 40% or higher, skin water content can be increased to 50% or higher, pore shrinkage and skintightening are achieved, wrinkles are eliminated, skin aging is prevented, stratum corneum is adjusted, skin transparency is improved, moisture retention effect is enhanced, skin barrier function is improved, long lasting moisture retention is achieved. The formula of the honey essence is extremely mild, no skin irritation is caused, the preparation technology is simple, and the composition is safe to use.

The invention discloses skin-care cream with instant firming and anti-aging effects and preparation thereof. The skin-care cream with the instant firming and anti-aging effects contains 0.01 to 10.0%of active ingredient ceramide compound, 0.001 to 0.005% of magnesium gluconate, 0.001 to 0.005% of copper gluconate, 0.1 to 5.0% of brown algae extract, 0.1 to 5.0% of rhodophyta algae extract, 0.01 to 5.0% of hydroxypropyl tetrahydropyrantriol, 0.01 to 10.0% of retinol and 0.05 to 0.2% of arginine/lysine polypeptide. The cream prepared by the invention is stable in property, excellent in skin-friendliness and rapid in adsorption, and not only can instantly lift and firm skin and implement instantly beautiful skin, but also can improve skin elasticity, reduce thin wrinkles, improve the overallskin aging condition, implement long-acting aging resistance of the skin and obviously solve the skin aging problem after being used for long time.

The invention provides a mesotherapy composition. Based on the total weight of the mesotherapy composition, the mesotherapy composition comprises: 0.01-10 wt% of hyaluronic acid-based components and 0.01-10 wt% of adjuvants, with the balance being water; and the hyaluronic acid-based components include: hyaluronic acid, hyaluronic acid metal salts and hyaluronic acid modified products. The invention also provides application of the mesotherapy composition in the mesotherapy for resisting skin aging signs and application of the mesotherapy composition in the preparation of medicines or cosmetics for treating chloasma. The mesotherapy composition and the application thereof can improve the skin aging problems of dry skin, fine lines, dry lines, sagging, etc., can improve the skin color problems of dark skin, sallow skin, chloasma, etc., and can fundamentally improve the skin quality.