A sealed and semi-sealed ambient air pollution integral purification treatment technology is characterized in that a pollution air inlet (1) and a clean air outlet (2) are mainly included, and a filter material primary purification unit, a filter material high purification unit, an efficient sterilization unit, an adsorption catalysis unit, a mixed material adsorption unit, an oxidoreduction unit, an activated adsorption unit, a PICCO resolving unit and a negative oxygen ion generating unit are further included. The technology has the function that a plurality of purification technologies are adopted in a combined mode to integrally purify and treat a plurality of air pollutants such as PM10, PM2.5, pollen, CO, NOX, SO2, HC, formaldehyde, benzene, xylene, CO2, O3, TVOC, B(a), P, dioxin and various kinds of bacteria, meanwhile, the content of negative ions in the air is increased, and clean air is provided for people in various complex environments. Meanwhile, a plurality of purification modules are arranged in a standardization mode, and can be freely combined according to different use environments, and purification treatment of air in various environments can be efficiently completed.