34 results about "Cerebral concussion" patented technology

Provided is a method of diagnosing and / or monitoring mild traumatic brain injury (mTBI) or concussion in a subject. The method comprises determining a level of at least one miRNA in a saliva sample from the subject. Also provided is a sensor element, a detection system, composition and a kit for diagnosing and / or monitoring TBI, and a method of determining an appropriate treatment for a subject with suspected mTBI or concussion.

The disclosure provides neck collar devices and systems for the mitigation and prevention of traumatic brain injury, including concussion. Specifically disclosed are adjustable collars and systems, and collars having certain pressure sensing devices.

The invention belongs to the field of traditional Chinese medicinal preparations and particularly relates to a traditional Chinese medicinal preparation for treating cerebral concussion, which is characterized by being prepared from the following raw materials in part by weight: 2 parts of szechuan lovage rhizome, 2 parts of angelica dahurica, 3 parts of kudzu root, 2 parts of grassleaf sweelflag rhizome, 3 parts of salvia miltiorrhiza bunge, 3 parts of herba lycopi and 2 parts of tall gastrodia tuber. The traditional Chinese medicinal preparation is developed through years of clinic practice according to diagnosis and treatment based on an overall analysis of the illness and the patient's condition in the traditional Chinese medicine. The medicines are combined to produce the effects of activating blood, opening cardiac orifice and awakening consciousness. When used for treating cerebral concussion, the traditional Chinese medicinal preparation has the characteristics of exact effect, no side effect, high cure rate, quick effectiveness, convenience for administration and the like.

The present invention is oryzanol liposome with high absorption, high bioavailability and high stability and its preparation. The oryzanol liposome or oryzanol liposome precursor is prepared with oryzanol and phosphatide, cholesterol, supporting agent and other supplementary material. It has phosphatide / medicine weight ratio of 0.1-40, and is prepared through ethanol injecting process, film dispersion process, inverse evaporation process, extruding process or mechanical process. The supporting agent may be sorbitol, mannitol, cane sugar, etc. and has ratio to phosphatide of 0.01-400. The oryzanol liposome can act selectively on the autonomic nerve system of interbran and the center of endocrine system to improve autonomic nerve system, endocrine system and psychonerve. It is suitable for treating neurosis, climacteric syndrome, etc., and may be used in the assisting treatment of vascular headache and cerebral concussion sequelae.

The invention provides a traditional Chinese medicine composition for treating apoplexy and a preparation method thereof. The composition is prepared from astragalus root, angelica, cassia twig, wideearthworm, licorice, tuber fleeceflower, white peony root, peach kernel, rhizoma ligustici wallichii, chrysanthemum, tall gastrodia tuber and hawthorn. The traditional Chinese medicine composition fortreating apoplexy has the effects of promoting blood circulation, relieving the stasis of blood, promoting the circulation of qi, alleviating pain, reducing fever, relieving wind, lowering fat and resisting coagulation, is used for treating apoplexy and also can be used for treating diseases, such as cerebral concussion sequelae, cerebral arteriosclerosis and the like.

The invention belongs to the technical field of medical equipment, and particularly relates to a non-cranium-drill cranial ridge punching device for big and small mice, which mainly aims to solve the problems that when a traditional electric cranium drill is used for craniotomy, the pore diameter is difficult to adjust, the depth is uncontrollable, cerebral concussion can be easily caused due to the craniotomy carried out by the traditional electric cranium drill, and the like. The invention has the technical scheme that the non-cranium-drill cranial ridge punching device for the big and small mice comprises a handle, a fixing sleeve, an adjusting nut, a protection sleeve, a needle body connecting part, a needle body connecting petal, a fixing rod, a threaded rod and a needle body, wherein the needle body connecting part is arranged at the lower end of the handle, the needle body connecting petal is arranged at the lower end of the needle body connecting part, the upper end of the fixing rod is connected with the needle body connecting petal, the lower end of the fixing rod is connected with the upper end of the threaded rod, the lower end of the threaded end is connected with the needle body, the fixing sleeve is sleeved on the needle body connecting part, the adjusting nut and the protection sleeve are arranged on the threaded rod, and the adjusting nut is positioned above the protection sleeve. The non-cranium-drill cranial ridge punching device for the big and small mice, disclosed by the invention, has the advantages that the pore diameter is adjustable, the depth is controllable, the damage is low, and the operation is simple.

The present invention relates to organic salt of pyritinol as shown for treating cerebral concussion, brain trauma, encephalitis, meningitis sequelae and senile dementia. The organic salt exists in hydrate and is named as 3, 3-(dithio methylene) bis(5-hydroxy-6-methyl-pyridyl methane) organic salt chemically. The organic salt is salt of nicotinic acid, lactobionic acid, malic acid, etc. Experiments show that the organic acid and pyritinol have synergistic effect of protecting cardiac muscle, and the nicotinate of pyritinol is especially hopeful in developing pyritinol medicine.

A medicine for the treatment of sequelae of concussion, which is earthworm, frankincense, salvia, myrrh, red peony root, keel, oyster, safflower, chuanxiong, cohosh, Bupleurum, green bark, dendrobium, magnet, uncaria, and scorpion , Cyperus cyperi, chrysanthemum, and licorice are decocted with water to obtain a decoction. After concentration, add conventional excipients, add purified water until the crude drug content is 1g / ml, fill and sterilize to make an oral liquid preparation. The medicine of the present invention regulates qi and activates blood circulation, stimulates menstrual flow and relieves pain. For the treatment of sequelae of concussion, it not only takes effect quickly, but also makes pain disappear quickly, regulates qi and activates blood, removes stasis and relieves pain, attacks toxin and dissipates stagnation, and has a high cure rate and low recurrence rate in the treatment of sequelae of concussion. It has the effect of treating both symptoms and root causes, without sequelae, and the patient has no pain during the treatment period. The effective rate is 100% through clinical observation.

The invention discloses a traditional Chinese medicinal pill used for rehabilitation therapy of cerebral concussion and a preparation method thereof and belongs to the field of traditional Chinese medicines. The traditional Chinese medicinal pill used for the rehabilitation therapy of the cerebral concussion is prepared from the following effective raw material components in parts by weight: 65-80 parts of Chinese dates, 63-77 parts of longan aril, 60-74 parts of bamboo juice, 57-70 parts of polygonum multiflorum, 55-68 parts of potentilla anserina, 53-65 parts of glossy privet fruit, 50-62 parts of bark of eucommia, 43-58 parts of cortex albiziae, 40-55 parts of salviae miltiorrhizae, 38-52 parts of folium cycas, 35-48 parts of rhizoma corydalis, 32-45 parts of frankincense, 30-42 parts of corydalis amabilis, 28-40 parts of safflower, 25-37 parts of west china hypericum, 23-35 parts of curious kadsura root stem, 20-32 parts of ventilago leiocarpa benth, 18-28 parts of artemisia anomala, 15-25 parts of wooly datchmanspipe herb, 12-22 parts of arabian jasmine flower, 9-18 parts of benzoin, 6-14 parts of concha ostreae, 4-10 parts of liquorice and 2-7 parts of rhodiola rosea. The traditional Chinese medicinal pill used for the rehabilitation therapy of the cerebral concussion adopts medicinal materials which are adaptive and complementary in drug properties, implements action appropriate to the pathogenesis, has the effects of tonifying the liver and kidney, replenishing essence and nourishing brain, strengthening the spleen and stomach, benefiting qi and nourishing blood, activating blood and removing stasis, regulating qi to alleviate pain, eliminating stasis to subdue swelling as well as inducing resuscitation, is good in absorption effect and obvious in curative effect, produces no toxic or side effect and causes no clinical adverse reaction, and clinical verifications show that the traditional Chinese medicinal pill provided by the invention has high curative ratio on the cerebral concussion.

The invention relates to new pharmaceutical use of a Naozhenning preparation. As a traditional Chinese medicinal preparation, Naozhenning is widely applied in treatment of patients with cerebral concussion. The invention finds that through application of Naozhenning to a mouse traumatic brain injury model, cell death in the cortex and hippocampus are both less than that of a blank group, and the cortex defect degree is lighter than that of the blank group. At the same time, Naozhenning has an outstanding protective effect on cortical axons after injury, and also has certain degree of protection on dendritic branches and dendritic branch total length. Tests show that Naozhenning has neuroprotective effect on traumatic brain injury.

The invention discloses a lamp box for sleep of an infant. The lamp box comprises a sleep box, wherein the sleep box is a glass box and comprises a box body and a box cover arranged on the top of thebox body; a water tank is arranged on the inner wall of the box cover, a plurality of cleaning cotton pieces which are used for scrubbing and are of a hollow structure are arranged on the lower portion of the water tank, and reset springs are arranged between the cleaning cotton pieces and the water tank; the top of each cleaning cotton piece is provided with a telescopic pipe which is communicated with the water tank and the corresponding cleaning cotton piece separately; an jaundice phototherapy box used for irradiating the box body is arranged above the box cover, a rotating plate of a hollow structure is arranged in the middle of the box body, and a hand groove used for containing two hands of the infant is formed in the rotating plate, and a foot groove used for containing two feet ofthe infant is formed in the rotating plate; cotton cloth is arranged on the surface of the hand groove, and cotton cloth is arranged on the surface of the foot groove. The lamp box can assist the newborn infant in sleeping, and diseases such as cerebral concussion of the newborn infant can be prevented.

The invention relates to a medical appliance, in particular to a cerebral concussion treatment bed for implementing Mongolian medicine vibration therapy. The cerebral concussion treatment bed comprises a bed frame (1) and a bed surface (2) and is characterized in that a bowl-shaped vibration mortar (4) is arranged at one end of the bed surface (2), and a platy vibration sheet (5) is arranged at the other end of the bed surface (2) and is matched with a striking hammer (15). When in use, the shocked direction of the head of a patient is determined by observation or measurement, thereby applying reverse vibration to enable the brain tissue which deviates by shocking to return to the original position so that the brain tissue recovers. The cerebral concussion treatment bed provided by the invention is convenient for fixing the body of the patient, has the characteristics of high degree of mechanization, automation and standardization, simple structure, low cost, accurate parameters, obvious treatment effect and the like, and is simple and convenient to operate.

The invention discloses Tibetan medicine seventy-component pearl pellets. The Tibetan medicine seventy-component pearl pellets take seventy medicinal materials in an existing representative Tibetan medicine seventy-component pearl pill prescription as main raw materials; the seventy medicinal materials are classified according to mineral medicines, resin medicines, valuable medicines, rhizome medicines with a strong fiber property, rhizome medicines with a strong powdering property, volatile medicines, flower and leaf medicines, oily fruit medicines, powdery fruit medicines and animal medicines; the medicinal materials are crushed after the medicinal materials are mixed or are mixed after being separately crushed; finally, the crushed medicinal materials are mixed with a prepared bonding agent to prepare pills, namely a compound preparation. The Tibetan medicine seventy-component pearl pellets disclosed by the invention have the effects of calming nerves, tranquilizing, clearing and activating channels and collaterals, regulating qi and blood and inducing resuscitation; the Tibetan medicine seventy-component pearl pellets are mainly used for blood circulation system diseases and nervous system dysfunctions, disharmony of qi and blood, stroke, paralysis, hemiplegia, epilepsia, cerebral hemorrhage, cerebral concussion, heart diseases, hypertension and nervous disorder.

The disclosure provides neck collar devices and systems for the mitigation and prevention of traumatic brain injury, including concussion. Specifically disclosed are adjustable collars and systems, and collars having certain pressure sensing devices.

The invention discloses a dispersible traditional Chinese medicine tablet for treating cerebral concussion and a preparation method thereof, belonging to the technical field of traditional Chinese medicines. A machine used in the invention comprises an upper support, a lower support and electrical systems, wherein the lower support is arranged below the upper support, the electrical systems are located at two sides of the bottom of the lower support, the interior of the lower support is provided with a walking wheel mechanism and a water supply system, a hand-operated feeding mechanism is mounted between the upper support and the lower support, and a clamping mechanism, a wire rolling head, a rib-peeling cutter feeding-and-withdrawing mechanism and a speed reducer are arranged above the upper support. The objective of the invention is to provide the dispersible traditional Chinese medicine tablet for treating cerebral concussion and the preparation method thereof. The dispersible traditional Chinese medicine tablet has the characteristic of capacity of activating blood circulation, dispelling stasis, freeing the channels and activating collaterals, is used for treating the symptoms of headache, dizziness and memory deterioration occurred after cerebral concussion and has the advantages of stable curative effect, convenience in administration and carrying, fast absorption, high bioavailability and stable quality.

Photobiomodulation or low level light therapy is applied to the brain using a treatment protocol that shows improvement in treating a number of disease states and injuries of the brain. A laser probe including an LED cluster is placed perpendicular to the skull at a plurality of identified treatment points on the patient's skull for durations of 1 minute with pulsed waveforms at each location. The pattern for the treatment points varies by disease or injury state being treated. The treatment period is typically on nonconsecutive days for 6 weeks (3 times per week) or 9 weeks (2 times per week) per treatment protocol. Patients with Parkinson's disease, Alzheimer's disease, balance issues, concussions, depression, strokes, and other brain diseases or injuries have shown dramatic improvement under such treatment protocols.

The invention discloses a traditional Chinese medicine preparation for treating cerebral concussion, and belongs to the technical field of traditional Chinese medicines. Aiming at the causes of formation of concussion, an inventor selects the traditional Chinese medicines, of rauwolfia twig and leaves, shrubby breynia roots, papillose epipactis, piliferousstem aster herb, glabrous gardneria stem, Chinese ixora roots, hispid Chinese knotweed roots, salviae miltiorrhizae, velvety clovershrub roots, fivelobed grape, tuber fleeceflower stem, medical angiopteris rhizome, alpine swertia, irkutsk anemone rhizome and benzoin, with the effects of activating blood circulation, opening orifices, inducing resuscitation, ascending lucidity, descending turbidity and promoting blood circulation to remove blood stasis to prepare a decoction according to the theory of traditional Chinese medicine syndrome differentiation. Through a clinical experiment, the total effective rate reaches 96%.

The invention discloses pre-emulsified propylgallate concentrate for treating cardiovascular diseases as well as the preparation method and pharmaceutical application thereof. The pre-emulsified concentrate comprises propylgallate, oil phase, surfactant, latent solvent, and the like and is used for treating ischemic cerebrovascular diseases such as acute cerebral infarction, chronic cerebral thrombosis, lacunar cerebral infarction and cerebral vascular insufficiency as well as brain coma sequela, cerebral trauma, cerebral concussion, coronary heart disease, angina pectoris, hypertension, congestive heart failure, pulmonary heart disease and peripheral angiopathies such as thrombophlebitis, and the like.

The invention provides a traditional Chinese medicine preparation for treating cerebral concussion and a preparation method thereof. The traditional Chinese medicine preparation comprises the following raw medicines: filifolium sibiricum, hemp-leaved vitex root, whiteflower wisteria root, cassiope selaginoides, tinospora sinensis merr, piper sarmentosum, textile screw pine seed, camphor tree, pungent litse root-bark, sowthistle-leaf ixeris seedling, daphne feddei, caesalpinia cucullata, membranaceous beautyleaf root, lyonia ovalifolia, fimbriate calanthe pseudobulb, field melasma herb and pine needles. The traditional Chinese medicine preparation for treating cerebral concussion is safe and convenient to use; and by matching with the Western medicine conventional method for treating cerebral concussion, the curative effect is good, toxic or side effects and adverse reactions are avoided, the effect taking speed is high, and the preparation process is simple.

The invention discloses a traditional Chinese medicinal preparation for treating cerebral concussion, and belongs to the technical field of traditional Chinese medicine. In years of clinic treatment practice, the inventor, aiming at the pathogeny of the cerebral concussion and according to the theory of symptom differentiation in traditional Chinese medicine, decocts traditional Chinese medicinal materials with the effect of regulating vital energy, promoting blood circulation, eliminating phlegm and dredging intestines with water to obtain a decoction. The traditional Chinese medicinal materials include angiopteris offiacinalis, inula salsoloides, cephalanthus occidentalis, galium aparine, helicteres isora, cyperus difformis and cornus officinalis. Clinical tests show that total effective rate reaches 100%, obviously better as compared with that of control groups, and side effects are avoided. Especially, the traditional Chinese medicinal preparation has good curative effect on hypertensives.

The invention discloses a traditional Chinese medicine preparation for treating cerebral concussion sequelae. The traditional Chinese medicine preparation is produced from white paeony root, common macrocarpium fruit, nutgrass galingale rhizome, amber, cinnabar, radix bupleuri, akebia stem, peach kernel, chrysanthemum, simpleleaf shrub chastetree fruit, safflower, pseudo-ginseng, dens draconis, spina date seed, milkvetch root and ground beetle; the traditional Chinese medicine preparation is obtained after a plurality of times of clinical combination on the basis of replenishing qi and nourishing blood, removing stasis to ease pain and tonifying kidney and nourishing liver. After the traditional Chinese medicine preparation is taken, the medicine directly reaches the disease location, the effects of nourishing blood and benefiting qi, and nourishing liver and kidney are achieved, and the essence and the blood are enabled to flourish, and therefore, the brain qi and blood are sufficient, the blocked collaterals are dredged smoothly, the pain is removed, the microcirculation of the brain is improved, and the neurological function of the brain also can be recovered; as a result, the purpose of fundamentally curing the cerebral concussion sequelae is achieved.

The invention relates to the technical field of traditional Chinese medicine processing, in particular to a medicine combination used for treating brain diseases and a preparation method thereof. The medicine combination is prepared from malt, rice sprouts, ficus tikouaBur., gaultheria yunnanensis, shiny-leaved birch roots, vernonia cinerea and rosa laevigata. The medicine combination has a very good curative effect on brain trauma, brain trauma sequela, cerebral concussion, persistent vegetative state caused by cerebral concussion, brain atrophy, brain atrophy meridian disorders, brain rheumatism, cerebral infarction, cerebral blood stasis, hydrocephalus, brain qi blood blocking, neurological disorders caused by encephalitis, heart and brain vessel disorders, brain tissue neurological disorders (mental disorders) and brain tumors. The medicine combination can also help digestion, expel pus and eliminate swellings, clear away heat and toxin, diminish inflammation and relieve pain, strength the stomach and help to digest and has the sterilization and stasis removing functions, and the medicine combination has a good assisting effect on preventing intestinal cancer and diabetes and can regulate the qi blood high-low balance of human bodies.

The invention discloses a traditional Chinese medicine preparation for treating cerebral concussion and a preparation method thereof, belonging to the field of traditional Chinese medicine. The traditional Chinese medicine preparation disclosed by the invention consist of the following active ingredients: Polygonum cuspidatum, herba schizonepetae, Syzygium aromaticum, rhizoma acori graminei, Lycium barbarum L., Agastache rugosus, bark of Chinese catalpa, dens draconis, fermented soya beans, Leucas zeylanica (L.) R. Brown, pig brain, wild chervil, Dian Notopterygium incisum Ting, Exidia auricula Judae, perilla stem and fruit of Highland Barley malt; the traditional Chinese medicine preparation disclosed by the invention has the efficacies of elevating clear qi to lower turbid qi, promoting blood circulation to remove blood stasis, regulating the liver and nourishing the heart, has a significant curative effect on the treatment of symptoms such as transient coma, ecmnesia, headache, nausea and vomiting caused by cerebral concussion, is suitable in medicinal material compatibility, low in cost, and high in safety performance, without any toxic or side effects, and can achieve the purpose of treating both symptoms and root causes for the treatment of the cerebral concussion, thus being worthy of wide promotion and application in clinic.

The invention discloses a medicament for treating cerebral concussion and traumatic injury, which is characterized by comprising the following raw materials in part by weight: 40 to 50 parts of root of sharpspur corydalis, 10 to 20 parts of begonia fimbristipula and 30 to 40 parts of dutchmanspipe root. A preparation method for the medicament comprises the following steps of: weighing root of sharpspur corydalis, begonia fimbristipula and dutchmanspipe root according a weight ratio, mixing uniformly, crushing into fine powder and filtering; and preparing into tablets or capsules according to the conventional process. The medicament takes root of sharpspur corydalis and begonia fimbristipula as a chief medicament and dutchmanspipe root as a deputy medicament, and root of sharpspur corydalis, begonia fimbristipula and dutchmanspipe root are natural Chinese medicinal herbs; and in a formula of the medicament, the functional characteristics of the raw material medicaments are utilized fully, so the medicament for treating the cerebral concussion and the traumatic injury is quick in effectiveness and short in treatment course. In addition, the preparation method is simple and low in cost.

One aspect of the present invention provides a new use of butylphthalide, which relates to the use of butylphthalide or its derivatives in the preparation of medicines for treating or preventing concussions caused by accidents.

The invention provides a novel riding protective device. An inner shell is arranged inside an outer shell; a through hole is formed in the right side of the outer shell; shielding mirrors are assembled on two sides of the through hole through a rotating shaft; buffering cotton is distributed inside the inner shell, and damping columns are assembled between the outer shell and the inner shell; an LED lamp is arranged on the left side of the outer shell; a solar photovoltaic panel is positioned at the upper side of the outer shell and is fixed through a bolt; rainwater can be shielded by addingthe shielding mirrors; the solar photovoltaic panel is used for transforming solar energy into electric energy for storage, so that the energy-saving property can be greatly improved; the LED achievesthe aim of warning rear vehicles, so that the rider safety is greatly improved; reflective bars can be used for further improving the rider safety; and the design of buffering cotton achieves the aimof protecting a patient head, and is matched with the damping columns to absorb kinetic energy on the outer shell, and the problem of cerebral concussion of the rider can be prevented.

The invention discloses a drug for treatment of cerebral concussion sequelae and a preparation method thereof. The drug is mainly prepared from herba siegesbeckiae, Codonopsis pilosula, achyranthes root, chicken's gizzard-membrane, human placenta, spina date seed, dragon's blood, Salvia Miltiorrhiza, fallopia multiflora, Uncaria rhynchophylla, Flos Inulae, curcuma aromatic, peach kernel, gastrodia elata, cattail pollen, coix seed, chrysanthemum, drynaria rhizome, Radix Dipsaci, dragon bone, kudzuvine root, radix bupleuri and cortex mori according to certain weight ratio. The drug provided by the invention has the functions of quieting heart and soothing nerves, replenishing qi and nourishing blood, reinforcing liver and kidney, regulating blood vessels, tonifying spleen and boosting essence, and has the characteristics of quick effect, good curative effect and no recurrence in treatment of cerebral concussion sequelae.

The present invention provides a medicine for treating cerebral concussion tumors and a preparation technology thereof. The traditional Chinese medicine is a medicinal agent prepared from 5 raw materials of descurainia sophia, pycreus globosus, rhizoma cyperi, rhizoma gastrodiae and fresh gingers according to a ratio. The preparation technology is as follows: water is added to the 5 traditional Chinese medicine raw materials, decocting is conducted for twice, two filtrates are blended, then concentration and alcohol precipitation are conducted, cooling is conducted until a paste is obtained, and then the paste is dried to be prepared into granules, tablets or capsules. The medicine has good therapeutic effects on treating broad spectrum type cerebral concussion tumors, and is also non-toxic, safe, free of side effects and low in cost.

The invention discloses a medicament for treating cerebral concussion and traumatic injury, which is characterized by comprising the following raw materials in part by weight: 40 to 50 parts of root of sharpspur corydalis, 10 to 20 parts of begonia fimbristipula and 30 to 40 parts of dutchmanspipe root. A preparation method for the medicament comprises the following steps of: weighing root of sharpspur corydalis, begonia fimbristipula and dutchmanspipe root according a weight ratio, mixing uniformly, crushing into fine powder and filtering; and preparing into tablets or capsules according to the conventional process. The medicament takes root of sharpspur corydalis and begonia fimbristipula as a chief medicament and dutchmanspipe root as a deputy medicament, and root of sharpspur corydalis, begonia fimbristipula and dutchmanspipe root are natural Chinese medicinal herbs; and in a formula of the medicament, the functional characteristics of the raw material medicaments are utilized fully, so the medicament for treating the cerebral concussion and the traumatic injury is quick in effectiveness and short in treatment course. In addition, the preparation method is simple and low in cost.