The invention provides a flexible display panel motherboard and a manufacturing method of a flexible display panel, and relates to the technical field of display. The problem that in the manufacturing process of an existing flexible display panel, because a base coat is separated from a carrier substrate, mote is generated, the surrounding technological environment is polluted is solved. The flexible display panel motherboard comprises a carrier substrate and at least one flexible display panel unit formed on the carrier substrate, wherein the flexible display panel unit comprises a base coat, a flexible substrate and a display component which are all formed on the carrier substrate, the base coat of the flexible display panel unit comprises a first area and a second area, the laser absorptivity of the part, in the first area, of the base coat is lower than that of the part, in the second area, of the base coat, the critical energy of the part, in the second area, of the base coat is no larger than the critical energy of the part, in the first area, of the base coat, and the first area is located in the area of the edge of the flexible display panel unit.