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39 results about "Cyclohexane carboxylate" patented technology

Method for preparing calcium3-oxido-5-oxo-4-propionyl cyclohex-3-enecarboxylate

The invention discloses a method for preparing calcium3-oxido-5-oxo-4-propionyl cyclohex-3-enecarboxylate. According to the method for preparing calcium3-oxido-5-oxo-4-propionyl cyclohex-3-enecarboxylate, diethyl maleate and acetone are used as raw materials, Michael addition is conducted under the catalytic action of diethylamine, Claisen condensation is conducted under the action of organic alkali, after acidification is conducted through an organic acid or a mineral acid of a non-aqueous solvent or phenols having acidity, 5-Carboxycyclohexane-1,3-dione is obtained, acylation, rearrangement, hydrolysis and a salt forming reaction are conducted under the action of acid-binding agent, and then the target product, prohexadione-calcium, can be obtained. According to the method for preparing calcium3-oxido-5-oxo-4-propionyl cyclohex-3-enecarboxylate, six steps of reactions are completed in a one-pot mode, and the problem that waste water, waste residues and the like generated in the reaction process of each step pollute the environment is solved. The preparation method of calcium3-oxido-5-oxo-4-propionyl cyclohex-3-enecarboxylate has the advantages that operation is easy, column chromatography chromatograph is not needed, the preparation cost is low, environmental friendliness is achieved, and the preparation method is suitable for industrial production.
Owner:JIANGXI AGRICULTURAL UNIVERSITY

Adhesive agent composition for multilayer semiconductor

Provided is an adhesive composition for multilayer semiconductors. The adhesive composition gives, when applied and dried by heating, an adhesive layer that has approximately no adhesiveness at a temperature lower than 50° C., but, when heated at such a temperature as to less cause damage to semiconductor chips, offers adhesiveness and is rapidly cured thereafter. This adhesive composition for multilayer semiconductors includes a polymerizable compound (A), at least one of a cationic-polymerization initiator (B1) and an anionic-polymerization initiator (B2), and a solvent (C). The polymerizable compound (A) contains 80% by weight or more of an epoxide having a softening point or melting point of 50° C. or higher. The cationic-polymerization initiator (B1) gives a composition having a thermal curing time of 3.5 minutes or longer at 130° C., where the composition contains 1 part by weight of the cationic-polymerization initiator (B1) and 100 parts by weight of 3,4-epoxycyclohexylmethyl (3,4-epoxy)cyclohexanecarboxylate. The anionic-polymerization initiator (B2) gives a composition having a thermal curing time of 3.5 minutes or longer at 130° C., where the composition contains 1 part by weight of the anionic-polymerization initiator (B2) and 100 parts by weight of bisphenol-A diglycidyl ether.
Owner:DAICEL CHEM IND LTD

Preparation method of trinexapac-ethyl and intermediate thereof

The invention discloses a preparation method of trinexapac-ethyl and an intermediate thereof. The method comprises the following steps: under the action of an alkali, reacting acetoacetic ester (I) with diethyl maleate to obtain an intermediate (II), continuing reaction under the action of an acid to obtain diethyl 2-acetonyl-1,4-succinate; cyclizing the diethyl 2-acetonyl-1,4-succinate in the presence of an alkali, and acidifying to obtain ethyl 3,5-cyclohexyldione-formate; esterifying the ethyl 3,5-cyclohexyldione-formate and cyclopropyl formyl chloride in the presence of an acid-binding agent to obtain ethyl 4-cyclopropylformacyl-3,5-dione cyclohexane-carboxylate; and carrying out reaction on the end product under the actions of an organic alkali and a catalyst to obtain the trinexapac-ethyl. The technique has the advantages of favorable reaction selectivity, high yield and fewer byproducts, and is beneficial to obtaining the high-quality trinexapac-ethyl product. The method does not have high requirements for equipment, and avoids high-temperature high-pressure reaction. The method has the advantages of simple technique and mild reaction conditions, and is suitable for industrialization.
Owner:MAX RUDONG CHEM

Cationization silk fibroin and preparation method thereof

The invention discloses a cationization silk fibroin and a preparation method thereof, and belongs to the technical field of medical high-molecular materials. The cationization silk fibroin is obtained through reaction by coupling protamine sulfate mediated by water-soluble 2-imido thiacyclopentane hydrochloride with silk fibroin activated by sulfo-succinimido-4-[N-maleimide methyl]-cyclohexane-1-carboxylate. The cationization silk fibroin disclosed by the invention has the advantages of good biocompatibility and degradability, controllability in surface charge density, effective DNA (Deoxyribonucleic Acid) compression and protection capacity, higher transfection efficiency and uniqueness in cell targeting and cell nucleus positioning function. The cationization silk fibroin disclosed by the invention can form a cationization silk / gene compound with a gene substance through electrostatic action, and the cationization silk / gene compound is a novel biodegradable cationization silk gene transfer vector with cell targeting and a cell nucleus positioning function.
Owner:SUZHOU UNIV

Cationic silk fibroin/gene compound, and preparation method and application thereof

The invention discloses a cationic silk fibroin / gene compound, and a preparation method and application thereof and belongs to the technical field of polymeric biomaterials. The cationic silk fibroin / gene compound, and the preparation method and application thereof are characterized in that a cationic silk gene transmission carrier which has cell targeting and cell nucleus positioning functions and can be biodegraded is established and is obtained through the following steps: protamine sulfate is mediated by a water-soluble 2-imino thiacyclopentane hydrochloride to be in coupled with and react with the silk fibroin activated by sulfo-succunyl imino group-4-[N-maleimide methyl]-cyclohexane-1-carboxylic ester; the combination and a gene matter form the cationic silk fibroin / gene compound through electrostatic interaction. According to the invention, the cationic silk fibroin / gene compound has good biocompatibility and degradability, is controllable in surface charge density, can be effectively compressed and protect DNA, is relatively high in transfection efficiency, and has the particular cell targeting and cell nucleus positioning functions.
Owner:SUZHOU UNIV

Polyester based copolymer resin and molded product comprising the same

There are provided a polyester based copolymer resin capable of having an excellent shrinkage rate and being heat-shrunk at a low temperature, and a molded product comprising the same. The polyester based copolymer resin includes a dicarboxylic acid-derived residue including a residue derived from an aromatic dicarboxylic acid; and a diol-derived residue including a predetermined residue derived from 4-(hydroxymethyl)cyclohexylmethyl 4′-(hydroxymethyl)cyclohexane carboxylate and a predetermined residue derived from 4,4-(oxybis(methylene)bis)cyclohexane methanol.
Owner:SK CHEM CO LTD

Preparation method for high-purity edoxaban intermediate

The invention discloses a preparation method for the high-purity edoxaban intermediate (1S,3R,4R)-3-tertbutyloxycarbonylamino-4-hydroxy-naphthenic acid. The preparation method comprises the followingsteps: with 3-amino-4-hydroxy-cyclohexane carboxylate as shown in a formula (IV) which is described in the invention as a raw material, subjecting the raw material to protection by an amino protectivegroup so as to obtain 3-tertbutyloxycarbonylamino-4-hydroxy-cyclohexane carboxylate as shown in a formula (V) which is described in the invention; and carrying out enzyme hydrolysis and splitting soas to obtain optically pure (1S,3R,4R)-3-tertbutyloxycarbonylamino-4-hydroxy-naphthenic acid as shown in a formula (VI) which is described in the invention. The preparation method provided by the invention has the advantages of simple operation, environmental protection, high selectivity, low cost and the like, can realize large-scale industrial production, and is convenient for industrial promotion and application.
Owner:ASTATECH CHENGDU BIOPHARM CORP

Thermo-shrinkable polyester film

This disclosure relates to a thermo-shrinkable polyester film with excellent UV absorbance and heat resistance. According to one embodiment of the invention, provided is a thermo-shrinkable polyester film comprising a first resin layer comprising polyester resin comprising residues of dicarboxylic acid components comprising aromatic dicarboxylic acid, and residues of diol components comprising 4-(hydroxymethyl)cyclohexylmethyl 4′-(hydroxymethyl)cyclohexanecarboxylate, and 4,4-(oxybis(methylene)bis)cyclohexane methanol; and a second resin layer comprising the polyester resin and a UV absorber, formed on at least one side of the first layer.
Owner:SK CHEM CO LTD

Heat shrinkable film comprising polyester based copolymer

There is provided a heat shrinkable film comprising a polyester based copolymer capable of having an excellent shrinkage rate and being heat shrunk at a low temperature. The heat shrinkable film according to an exemplary embodiment of the present invention includes a polyester based copolymer, wherein the polyester based copolymer includes: a dicarboxylic acid-derived residue including a residue derived from an aromatic dicarboxylic acid; and a diol-derived residue including a residue derived from 4-(hydroxymethyl)cyclohexylmethyl 4′-(hydroxymethyl)cyclohexane carboxylate represented by the following Chemical Formula 1 and a residue derived from 4,4-(oxybis(methylene)bis) cyclohexane methanol represented by the following Chemical Formula 2.
Owner:SK CHEM CO LTD

Production method of 4-cyclopropyl (hydroxy) methylene -3,5-diketone ethyl cyclohexane carboxylate and recycling method thereof

The invention relates to the field of the organic synthesis, and discloses a production method of 4-cyclopropyl (hydroxy) methylene -3,5-diketone ethyl cyclohexane carboxylate and a recycling method thereof. The recycling method comprises the following steps: (1) enabling a liquid mixture containing the compound as shown in formula (1) to contact with metal ion in a first organic solvent under a complexation condition, and performing solid-liquid separation to obtain solid phase and liquid phase, wherein the metal is one or multiple metal elements in the ninth line, the tenth line, the eleventh line and the twelfth line of an element periodic table, and the pH value of the liquid mixture is greater than 6; (2) under a ligand dissociation condition, enabling the solid phase to contact withprotonic acid in the second organic solvent to obtain the organic phase and aqueous phase containing the compound as shown in formula (1), optionally separating the compound as shown in formula (1) from the organic phase. Through the method disclosed by the invention, the compound as shown in formula (1) with high purity can be recycled from the waste liquid in a comparatively high yield.
Owner:NUTRICHEM LAB CO LTD

Application of catalyst, and preparation method for disubstituted cyclohexane carboxylate with adjustable cis-trans ratio

The invention relates to application of a catalyst, and a preparation method for disubstituted cyclohexane carboxylate with an adjustable cis-trans ratio. The catalyst is used for adjusting the cis-trans ratio of disubstituted cyclohexane carboxylate produced by a hydrogenation reaction of aromatic carboxylate. The preparation method comprises a step of, with aromatic carboxylate as a raw material, carrying out a hydrogenation reaction in the presence of the catalyst so as to produce disubstituted cyclohexane carboxylate, wherein the produced disubstituted cyclohexane carboxylate comprises cis-disubstituted cyclohexane carboxylate and trans-disubstituted cyclohexane carboxylate, and the active component of the catalyst is one or more selected from a group consisting of Ru, Pd and Ni. Withthe preparation method, cis-disubstituted cyclohexane carboxylate and trans-disubstituted cyclohexane carboxylate in different ratios can be prepared; when the active component of the catalyst is Ni,cis-disubstituted cyclohexane carboxylate accounts for 40 to 65%; when the active component of the catalyst is Ru, cis-disubstituted cyclohexane carboxylate accounts for 75 to 90%; and when the activecomponent of the catalyst is Pd, cis-disubstituted cyclohexane carboxylate accounts for 95 to 98%.
Owner:SHANGHAI HUAYI ENERGY CHEM

Heat shrinkable film comprising polyester based copolymer

There is provided a heat shrinkable film comprising a polyester based copolymer capable of having an excellent shrinkage rate and being heat shrunk at a low temperature. The heat shrinkable film according to an exemplary embodiment of the present invention includes a polyester based copolymer, wherein the polyester based copolymer includes: a dicarboxylic acid-derived residue including a residue derived from an aromatic dicarboxylic acid; and a diol-derived residue including a residue derived from 4-(hydroxymethyl)cyclohexylmethyl 4′-(hydroxymethyl)cyclohexane carboxylate represented by the following Chemical Formula 1 and a residue derived from 4,4-(oxybis(methylene)bis) cyclohexane methanol represented by the following ChemicalFormula 2.
Owner:SK CHEM CO LTD

Heat shrinkable film composition comprising polyethyleneterephtalate resin and polyester based copolymer, and heat shrinkable film

There is provided a composition for forming a heat shrinkable film capable of providing a heat shrinkable film capable of having an excellent shrinkage rate and being heat-shrunk at a low temperature. The composition for forming a heat shrinkable film includes a polyethylene terephthalate (PET) resin having an inherent viscosity of 0.50 to 1.2 dl / g, and a polyester based copolymer including a dicarboxylic acid-derived residue including a residue derived from an aromatic dicarboxylic acid and a diol-derived residue including a residue derived from 4-(hydroxymethyl)cyclohexylmethyl 4′-(hydroxymethyl)cyclohexane carboxylate represented by the following Chemical Formula 1 and a residue derived from 4,4-(oxybis(methylene)bis) cyclohexane methanol represented by the following Chemical Formula 2.
Owner:SK CHEM CO LTD

Preparation method of prohexadione calcium

The invention discloses a preparation method of prohexadione calcium. The preparation method comprises the following steps: preparing a calcium acetate aqueous solution with mass percentage concentration of 20-30%, adding 3,5-dioxo-4-propionyl ethyl cyclohexane carboxylate into the calcium acetate aqueous solution, wherein a mass ratio of the aqueous solution to the 3,5-dioxo-4-propionyl ethyl cyclohexane carboxylate is (10 to 20) : 1; adding a lipase catalyst which accounts for 0.5-2% of the total mass, reacting for 2-10 hours at a temperature of 30-80 DEG C under stirring speed of 250-800 revolutions per minute, filtering and recycling the lipase catalyst, and cooling to separate out 3,5-dioxo-4-propionyl ethyl cyclohexane carboxylate, wherein the lipase catalyst is Novozyme 435, lipozyme RMIM or Lipozyme TLIM. The method does not use an organic solvent, is environmentally friendly, is high in yield and is high in purity.
Owner:浙江大鹏药业股份有限公司

Nickel-based halloysite nanotube hydrogenation catalyst and preparation and application thereof

The invention belongs to the field of cyclohexane carboxylate preparation, and particularly relates to a nickel-based halloysite nanotube hydrogenation catalyst and preparation and application thereof. According to the nickel-based halloysite nanotube hydrogenation catalyst, a halloysite nanotube serves as a carrier, an active component is loaded on the halloysite nanotube in an in-situ growth mode, and the active component is nickel or a combination of nickel and one or more of the following metal elements: Cu, W, Ce, Al, Pr, Y and B. The nickel-based halloysite nanotube hydrogenation catalyst provided by the invention has high activity and good selectivity, is suitable for hydrogenation production with naphthalene orthophthalic acid esters as raw materials, has a great cost advantage of the catalyst per unit product, and can also realize a very high raw material conversion rate after being repeatedly used for many times. Besides, according to the production process provided by the invention, the orthophthalic acid ester raw material in the final finished product is reduced to the ppm level, the refining cost of the product is greatly reduced, and the production process has a remarkable market cost advantage.
Owner:河南天宁新材料科技有限公司 +1

Cyclohexanecarboxylic acid ester preparation method

The present invention relates to a cyclohexanecarboxylic acid ester preparation method, wherein the compound is obtained by carrying out selective hydrogenation on a phthalic acid derivative, and the used hydrogenation catalyst is a Ni, Co, Mn and Al2O3-SiO2 composite nano-tube array film hydrogenation catalyst, wherein the catalyst has high activity and high selectivity in the cyclohexanecarboxylic acid ester preparation reaction through the selective hydrogenation of the phthalic acid derivative, and the hydrogenation product is a class of the wide-application plasticizers.
Owner:WANHUA CHEM GRP CO LTD

Alicyclic epoxy compound product

Provided is an alicyclic epoxy compound product used in applications for forming a cured product excellent in heat resistance and transparency.The alicyclic epoxy compound product according to an embodiment of the present invention includes 3,4-epoxycyclohexylmethyl(3,4-epoxy)cyclohexanecarboxylate, a purity of which is of not less than 98.5 wt. %, and each content of a compound represented by Formula (a) below, a compound represented by Formula (b) below, a compound represented by Formula (c) below, and a compound represented by Formula (d) below is not greater than 0.5 wt. %.
Owner:DAICEL CHEM IND LTD

Adhesive agent composition for multilayer semiconductor

Provided is an adhesive composition for multilayer semiconductors. The adhesive composition gives, when applied and dried by heating, an adhesive layer that has approximately no adhesiveness at a temperature lower than 50° C., but, when heated at such a temperature as to less cause damage to semiconductor chips, offers adhesiveness and is rapidly cured thereafter. This adhesive composition for multilayer semiconductors includes a polymerizable compound (A), at least one of a cationic-polymerization initiator (B1) and an anionic-polymerization initiator (B2), and a solvent (C). The polymerizable compound (A) contains 80% by weight or more of an epoxide having a softening point or melting point of 50° C. or higher. The cationic-polymerization initiator (B1) gives a composition having a thermal curing time of 3.5 minutes or longer at 130° C., where the composition contains 1 part by weight of the cationic-polymerization initiator (B1) and 100 parts by weight of 3,4-epoxycyclohexylmethyl (3,4-epoxy)cyclohexanecarboxylate. The anionic-polymerization initiator (B2) gives a composition having a thermal curing time of 3.5 minutes or longer at 130° C., where the composition contains 1 part by weight of the anionic-polymerization initiator (B2) and 100 parts by weight of bisphenol-A diglycidyl ether.
Owner:DAICEL CHEM IND LTD

Process for producing expandable styrene polymer compositions

A composition comprising at least one expandable styrene polymer component and at least one cyclohexanecarboxylic ester and also optionally further components can be processed to mechanically robust foam materials.
Owner:BASF AG

UV woodware paint for carbonized material, and manufacturing method thereof

The invention discloses a UV woodware paint for carbonized material, and a manufacturing method thereof. The UV woodware paint is prepared by taking epoxy acrylic resin, polyurethane acrylic resin, tetraethylammonium bromide, cobalt cyclohexane carboxylate, chitosan powder, adequate amount of absolute ethyl alcohol, titanium dioxide powder, fatty alcohol-polyoxyethylene ether, GST modified epoxy carbon-sticking glue, functional components extracted from cornu gorais, closed isocyanate, and defoaming agent as raw material and taking deionized water as the medium to sufficiently react at 70-85 DEG C, whereien the preparation process of the function components comprises infiltrating, dicing, braising, purifying and concentrating. The UV woodware paint disclosed by the invention has the technical effects of being dedicated to the carbonized wood surface, cured by ultraviolet, incapable of damaging the wood, high in adhesive force, high in wear resistance, high in permeation, and self-hydrophobic.
Owner:JIANGSU HIMONIA TECH
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