37 results about "Glucose / Sodium Chloride Injection" patented technology

The invention provides an antigen-specific T lymphocyte freezing medium, comprising freezing medium A and freezing medium B; the freezing medium A includes, by volume, 30-40% of plasmalyte electrolyte injection, 30-40% of glucose and sodium chloride injection, 5-15% of dextran glucose injection and 15-25% of human albumin solution; the freezing medium B includes, by volume, 20-30% of plasmalyte electrolyte injection, 20-30% of glucose and sodium chloride injection, 5-15% of dextran glucose injection, 15-25% of human albumin solution and 10-20% of dimethyl sulfoxide; the freezing medium A and the freezing medium B are stored separately; in use, the freezing medium A and the freezing medium B are mixed in a ratio of 1:(0.5-2), forming the antigen-specific T lymphocyte freezing medium. The antigen-specific T lymphocyte freezing medium is capable of enabling less crystal to form in cells, increasing cell survival rate and maintaining tumor-killing ability of cells. The invention also provides a preparation method and application of the antigen-specific T lymphocyte freezing medium and antigen-specific T lymphocyte injection.

The present invention is a hydroxypropyl β-cyclodextrin-containing ambroxol hydrochloride injection and a preparation method thereof, which completely solves the problem of water solubility, so that various injection preparations can be prepared. Ambroxol hydrochloride injection contains hydroxypropyl beta-cyclodextrin. The injection is realized by adding "2-hydroxypropyl β-cyclodextrin" to solve the solubility of ambroxol hydrochloride in high pH water, wherein "ambroxol hydrochloride" and "2-hydroxypropyl β-cyclodextrin" The weight ratio of "cyclodextrin" is 1:3 to 1:50. Said injection includes "injection", "lyophilized powder injection", "sterile powder injection", "ambroxol hydrochloride glucose, sodium chloride injection or glucose sodium chloride injection". The present invention can make ambroxol hydrochloride compatible with basic drugs, and is convenient for clinical medication.

The invention belongs to the technical field of medicine, and particularly relates to a cefotiam hydrochloride compound, a method for preparing the same and a pharmaceutical composition with the cefotiam hydrochloride compound. The cefotiam hydrochloride compound is cefotiam hydrochloride trihydrate, and a structural formula of the cefotiam hydrochloride compound is shown. The cefotiam hydrochloride compound, the method and the pharmaceutical composition have the advantages that crystals of the cefotiam hydrochloride trihydrate are good in flowability, injection cefotiam hydrochloride made of the crystals of the cefotiam hydrochloride trihydrate, 0.9% sodium chloride injection, 5% glucose injection and 5% glucose and sodium chloride injection can be compatible with one another to obtain liquor, and the liquor is excellent in stability after being placed at the room temperature for 4h.

The invention discloses a production process of glucose sodium chloride injection. The method comprises the following steps: step 1, weighing; step 2, concentrated preparation; step 3, thin preparation; Bacteria; Step 6: Light inspection; Step 7: Packaging. The production process of glucose sodium chloride injection provided by the present invention, the production process of glucose sodium chloride injection provided by the present invention, through strict control of the quality of raw materials, adjustment and optimization of the process flow, the content of insoluble particles, heavy metals, and bacterial endotoxins in the product Significantly reduced, due to the use of nitrogen filled potting, the product has good stability, and no additional antioxidant is needed, which further improves the safety of the injection, and the production efficiency of the optimized process and the qualified rate of the finished product are both significantly improved.

The invention discloses a process for pretreating glucose and sodium chloride injection, and belongs to the technical field of injection. The method comprises the following steps: (1) weighing raw materials; (2) dissolving the raw materials, namely a) adding sodium hydrogen sulfite, magnesium chloride, calcium chloride, sodium chloride and zinc sulfate into injecting water at 30-40 DEG C; (b) adding dipotassium phosphate, glucose, fructose, xylitol and sodium acetate into the injecting water at 50-60 DEG C; and (c) mixing the solution, adding citric acid and activated carbon, insulating and adsorbing; (3) decarburizing, delivering to a diluting tank; (4) complementing injecting water, and regulating the pH value to 6.5-7.5; (5) filling bags after rough filtration and fine filtration; and (6) sterilizing at 122 DEG C for 3-5 minutes. According to the process, raw materials are dissolved in batches with different dissolving temperatures, the dissolving speed is increased, the temperature is reasonably controlled, energy consumption and cost are reduced, the solution is uniformly mixed, and generation of glucose degraded products can be effectively reduced.